Breve resumen del tipo de neuropatias y enfermedades asociadas, y signos que nos podemos encontrar
Esta página es de una clínica de Alicante especializada en neurología. Hay muchos videos, radiografias..., pero tienes que estar registrado y certificar que eres estudiante o licenciado veterinario para que no te cierren la cuenta, además pagar por verlos; solo tienes acceso, gratis, a una sección: http://jgtube.vetjg.es/Neurologia/neurologia-cual-es-tu-diagnostico
estudio realizado, por la universidad de Ohio, a 104 caballos con convulsiones que intenta clasificar las crisis según su etiología. Es interesante debido a la escasa bibliografía sobre este tema en los equinos
Eleven dogs diagnosed with refractory idiopathic epilepsy were treated orally with gabapentin for a
minimum of three months at an initial dose of 10 mg/kg every eight hours. They were all experiencing
episodes of generalised tonic-clonic seizures and had been treated chronically with a combination of
phenobarbital and potassium bromide at doses sufficient to reach acceptable therapeutic serum levels
without causing significant side effects. In each dog, the number of seizures per week, the average duration
of the seizures and the number of days on which seizures occurred were compared for the three months
before and after they were treated with gabapentin. A minimum 50 per cent reduction in the number of
seizures per week was interpreted as a positive response to gabapentin, and six of the dogs showed a
positive response. After the addition of gabapentin, both the number of seizures per week (P= 0·005) and
the number of days with any seizures in a one-week period (P=0·03) were significantly reduced. Mild side
effects of ataxia and sedation were observed in five of the dogs, but they were not severe enough to warrant
the treatment being discontinued during the trial.
From the owners' perspective, adequacy of
seizure control is determined by the balance between ''the dog's
quality of life'', ''adequate seizure frequency'' and ''acceptable side
effects of antiepileptic drugs''. A frequency of less than one seizure
every three months is associated with the perception by owners of
adequate seizure control.
LEV was effective in reducing seizure frequency initially
in the majority of dogs with PB and KBr resistant epilepsy.
However, most of the dogs experienced an increase in their
seizure frequency and frequency of seizure days after 4-8
months. LEV was well tolerated in most dogs and the only
side-effect reported was sedation. However, further studies
would be necessary before to confirm the absence of behavioural
problems during LEV treatment.