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Artículo de Clare Rusbridge, especialista en neurología veterinaria, sobre la etiología de las convulsiones y cómo llegar a la causa

Breve resumen del tipo de neuropatias y enfermedades asociadas, y signos que nos podemos encontrar Esta página es de una clínica de Alicante especializada en neurología. Hay muchos videos, radiografias..., pero tienes que estar registrado y certificar que eres estudiante o licenciado veterinario para que no te cierren la cuenta, además pagar por verlos; solo tienes acceso, gratis, a una sección: http://jgtube.vetjg.es/Neurologia/neurologia-cual-es-tu-diagnostico

Artículo que compara las convulsiones, temblores y contracciones musculares para identificarlas y llegar a la causa

resumen del estudio

Muy antiguo, de 1994.

Artículo que describe la epilepsia idiopática y justifica un estudio para confirmar la existencia de genes asociados

estudio realizado, por la universidad de Ohio, a 104 caballos con convulsiones que intenta clasificar las crisis según su etiología. Es interesante debido a la escasa bibliografía sobre este tema en los equinos

Cuando el tratamiento típico no funciona, los medicamentos que se pueden considerar.

Eleven dogs diagnosed with refractory idiopathic epilepsy were treated orally with gabapentin for a minimum of three months at an initial dose of 10 mg/kg every eight hours. They were all experiencing episodes of generalised tonic-clonic seizures and had been treated chronically with a combination of phenobarbital and potassium bromide at doses sufficient to reach acceptable therapeutic serum levels without causing significant side effects. In each dog, the number of seizures per week, the average duration of the seizures and the number of days on which seizures occurred were compared for the three months before and after they were treated with gabapentin. A minimum 50 per cent reduction in the number of seizures per week was interpreted as a positive response to gabapentin, and six of the dogs showed a positive response. After the addition of gabapentin, both the number of seizures per week (P= 0·005) and the number of days with any seizures in a one-week period (P=0·03) were significantly reduced. Mild side effects of ataxia and sedation were observed in five of the dogs, but they were not severe enough to warrant the treatment being discontinued during the trial.

From the owners' perspective, adequacy of seizure control is determined by the balance between ''the dog's quality of life'', ''adequate seizure frequency'' and ''acceptable side effects of antiepileptic drugs''. A frequency of less than one seizure every three months is associated with the perception by owners of adequate seizure control.

LEV was effective in reducing seizure frequency initially in the majority of dogs with PB and KBr resistant epilepsy. However, most of the dogs experienced an increase in their seizure frequency and frequency of seizure days after 4-8 months. LEV was well tolerated in most dogs and the only side-effect reported was sedation. However, further studies would be necessary before to confirm the absence of behavioural problems during LEV treatment.