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Manejo multimodal del FLUTD Estadísticamente, las dos causas más frecuentes de Flutd son la Cistitis Idiopática felina (enunciada por multitud de nombres, idiomas y siglas: FIC, iFLUTD, Cistitis idiopática felina, Cistitis Intersticial, Cistitis Idiopática...) que representa cerca del 60 % de los gatos afectados y los urolitos (básicamente estruvita y oxalato cálcico) que representa cerca del 20% de los gatos afectados.

Artículo que describe la epilepsia idiopática y justifica un estudio para confirmar la existencia de genes asociados

Cuando el tratamiento típico no funciona, los medicamentos que se pueden considerar.

Eleven dogs diagnosed with refractory idiopathic epilepsy were treated orally with gabapentin for a minimum of three months at an initial dose of 10 mg/kg every eight hours. They were all experiencing episodes of generalised tonic-clonic seizures and had been treated chronically with a combination of phenobarbital and potassium bromide at doses sufficient to reach acceptable therapeutic serum levels without causing significant side effects. In each dog, the number of seizures per week, the average duration of the seizures and the number of days on which seizures occurred were compared for the three months before and after they were treated with gabapentin. A minimum 50 per cent reduction in the number of seizures per week was interpreted as a positive response to gabapentin, and six of the dogs showed a positive response. After the addition of gabapentin, both the number of seizures per week (P= 0·005) and the number of days with any seizures in a one-week period (P=0·03) were significantly reduced. Mild side effects of ataxia and sedation were observed in five of the dogs, but they were not severe enough to warrant the treatment being discontinued during the trial.

From the owners' perspective, adequacy of seizure control is determined by the balance between ''the dog's quality of life'', ''adequate seizure frequency'' and ''acceptable side effects of antiepileptic drugs''. A frequency of less than one seizure every three months is associated with the perception by owners of adequate seizure control.

LEV was effective in reducing seizure frequency initially in the majority of dogs with PB and KBr resistant epilepsy. However, most of the dogs experienced an increase in their seizure frequency and frequency of seizure days after 4-8 months. LEV was well tolerated in most dogs and the only side-effect reported was sedation. However, further studies would be necessary before to confirm the absence of behavioural problems during LEV treatment.

artículo que contiene claves para el diagnóstico y tratamiento de cada una de las posibles causas de este problema (relacionadas con la bandeja, marcaje o cistitis idiopática felina)