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For Dr. John Evans, growing a strong biotechnology industry is much the same: cities must provide a nurturing environment where science and business can thrive together.

That's why Evans, former president of the University of Toronto and current chairman of Torstar Corp., is spearheading the $345-million Medical and Related Science initiative, or MaRS--a petri dish of sorts for commercializing science research. "A lot of intellectual property is being commercialized outside Canada," says Evans. "I think we've been slow in realizing just how important technology developments are to the economic future of the country. MaRS is an attempt to give this a kick into a higher gear." The centrepiece of the MaRS plan, which will officially launch May 12, is a 1.3-million-square-foot, five-building complex in downtown Toronto that will provide office and lab space for small and medium-size companies and incubators, including the not-for-profit Toronto Biotechnology Commercialization Centre. While Evans is reluctant to limit its scope, MaRS will generally focus on health-related technologies, from new drugs and genetic treatments to medical devices and imaging software. Branded a "convergence centre," it will also house a careful mix of support services: intellectual property lawyers, accountants, marketing experts, government funding organizations and venture capital financiers. Plus, start-ups will have access to all the latest equipment on site. For instance, MaRS is in talks with MDS Sciex to supply mass spectrometers, used in proteomics research.

But MaRS will be more than just a New Economy real estate development. Evans's intention is to funnel tenants' rent money into services--such as entrepreneurship seminars and angel-matching programs--that MaRS will offer to the broader biotech community. That's why MaRS's location is key: the centre will be built in the heart of what Toronto has dubbed the "Discovery District," a two-square-kilometre chunk of the downtown core, encompassing U of T and four major hospitals. From there, MaRS hopes to act as a network hub across Ontario, with links to research-intensive universities. "None of them," says Evans, "have the critical mass to put it all together on their own."

We don’t know for sure,” said Dr. John Evans, chair of the board of directors at MARS (Medical and Related Sciences) Discovery District in Toronto, and vicechair of Mississauga, Ont.-based NPSAllelix Biopharmaceuticals, one of the pioneers of biotech in Canada. “But we believe that if you could ‘type’ the patient processes of how he/she handles a drug, you could peel off those people who would be particularly sensitive to a drug. Then you could find a sub-population where the drug is safe and highly effective.” Evans used the arthritis drug Vioxx as an example. It helped millions of people battle painful inflammation, but was pulled from the market recently because of potential cardiac side effects in some people. “If the drug company could have predicted which patients would have complications from Vioxx treatment — through some genetic profiling — then a very powerful and effective drug could have been preserved,” Evans said. His company, NPS-Allelix Bio-pharmaceuticals, has been developing a product since 1989 that will be launched later this year. The drug secretes a parathyroid hormone for treating osteoporosis.

It builds up bone matrix and helps build bone, rather than just delay bone loss as other drugs do.

In November, Skymeter moved into the incubator at the MaRS Centre, where marketing expert Peter Evans has become their mentor and godfather. "Being surrounded by other entrepreneurs is inspiring and enlightening," Hassan says. "MaRS is an amazing place, with excellent speakers and events that are open to the public."

The father of Skymeter Corp. – which developed a BlackBerry-sized device that uses GPS signals; placed in vehicles, it meters the use of roads, parking and pay-as-you-drive insurance

Skymeter's black box will be attached to the windshield of cars so the box has a clear view of the sky. (Grush has figured out how to cope with tall buildings blocking signals.) The box contains a GPS receiver, some memory, a processor and a telecommunications chip. The satellite beams down to the earth, the GPS receiver computes where it is and uploads its history to a data centre to generate the bill. The vehicle measures its own use; the bill is itemized like a cellphone bill. If you prepay, the bill can be calculated on board.

This is Toronto's research district, a maze of concrete and glass where the finest minds collaborate, turning the city into a global centre of biomedical discovery.

Nine research institutes employing 5,000 university faculty members, 2,000 graduate students and 1,100 postdoctoral and clinical fellows lie within a 20-minute walk of each other. This biomedical cluster at the heart of Toronto is one of the largest on the continent, and is one of the 10 largest in the world.

Tom Hudson from Montreal; cell biologist Ben Neel from Boston; and stem-cell biologist Gordon Keller, who came to Toronto in 2006, just months after New York magazine named him one of the scientists that city could not afford to lose. Toronto is also home to Tak Mak, who discovered the "key to the immune system" T-cell receptor, and John Dick, who discovered the first cancer stem cell in 1994 and last year grew a human cancer in a lab mouse for the first time.

At the AlwaysOn Stanford Summit, Aeryon Labs President Dave Kroetsch gave a compelling pitch on his company, which makes a two-pound robot helicopter that has enough on-board intelligence and stability control to allow it to be flown by people who just point to locations on a Google Map-based interface.

sell to private security forces, and eventually police departments

other markets include construction (for site surveys), other public safety applications, and of course military.

Between June 8-12, 2009, MaRS held our first ever Net Change, a week dedicated to exploring this intersection between social technology and social change.

Fourteen different Net Change events, including an art show, experimented with ways of creating and sharing information and knowledge on this question. Bridging the “digital divide” between web professionals and people creating social change, participants were from all different sectors and leadership levels. T

Net Change also addressed critical concepts such as how to measure the impact of social technology, and what we really mean by social change, while including storytelling to hit theoretical concepts home.

The temple has a conference room equipped with state-of-the-art audio-visual aids. Its board of directors includes several leading software billionaires and their wives, providing it with money as well as connections.

The monks are entrepreneurs as well as holy men, one moment talking about reincarnation and the next about sustainable delivery models.

he temple provides 200,000 local schoolchildren with free meals every day.