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"Evidence from skulls in east London shows plague had to have been airborne to spread so quickly"

Europe in the first half of the 14th Century seemed to be preparing itself for significant changes. Cities grew in importance, though most of the population was still rural. Population increases had led to overuse of the available land. Poor harvests-also due to cooler, wetter weather-led to famines. The serf system was being undermined. Centralized political authority was becoming more powerful. Then the Black Death cut a path-both literal and figurative-through the middle of the 14th Century. The disease was caused by the bubonic plague, which was spread by rats, whose fleas carried the plague bacilli from the East along trade routes until it penetrated almost all of Europe, killing at least one out of every three people. Such a radical alteration in population in any place, at any time, would likely set off dramatic changes in society. What happened in a Europe already beginning to transform itself? In this lesson, students analyze maps, firsthand accounts, and archival documents to trace the path and aftermath of the Black Death.

A third of Europe's population died over four years due to the Black Death. But was it really spread by rats and fleas? Could it have been caused by a virus? And what has that got to do with the modern-day spread of HIV?