"High-dose influenza vaccine appears to have the potential to prevent nearly one-quarter of all breakthrough influenza illnesses in seniors (≥65 y) compared with the standard-dose vaccine, according to results from a phase IIIb-IV double-blind, active-controlled trial.[3, 4] A total of 31,989 participants were randomly assigned to receive either a high dose (IIV3-HD) (60 μg of hemagglutinin per strain) or a standard dose (IIV3-SD) (15 μg of hemagglutinin per strain) of a trivalent, inactivated influenza vaccine. The multicenter trial was performed during the influenza seasons of 2011-2012 and 2012-2013 in Canada and the United States.[3, 4]"

"The best way to protect against influenza is to receive an influenza vaccination every year. CDC recommends that everyone six months of age and older receive an annual vaccination. The best time to get vaccinated is in the early fall, as soon as the vaccine is available. However, vaccination in December or even later is still beneficial because the virus that causes influenza circulates past the new year. The number of influenza cases usually peaks around February, but this peak can come earlier or later (ranging from December to May)."

"Influenza is a viral infection that attacks your respiratory system - your nose, throat and lungs. Influenza, commonly called the flu, is not the same as the stomach "flu" viruses that cause diarrhea and vomiting. Influenza and its complications can be deadly. People at higher risk of developing flu complications include: Young children Older adults Pregnant women People with weakened immune systems People who have chronic illnesses Your best defense against influenza is to receive an annual vaccination."