More than 1.5 million courses of Pfizer's COVID-19 antiviral drug Paxlovid have expired unused in European countries by the end of November, the health
analytics firm Airfinty has revealed.
It is predicted that the figure could surge to 3.1 million, at a value of $2.2 billion (around £1.73 billion), by the end of Feb 2024.
According to Airfinty analysis, Britain has the highest unused stock, with an estimated one million expired drug courses worth $700 million (over £550 million).
With 2.2 million courses estimated to expire unused by the end of June 2024 due to the low prescription of the antiviral in the country, the total drug value
wasted in the UK could reach $1.5 billion (£1.1 billion), the report added.
The Royal Pharmaceutical Society (RPS) has decided to lease two floors of its east London headquarters to Ingeus, a business with services in employment, health, justice and youth.
RPS will retain three floors of the building, including its museum and library on the ground floor, as well as the two upper floors which will be used for events, collaborative working and team meetings.
The decision follows an announcement in April that the the Society was re-evaluating whether it needed to hold on to its current office space as homeworking was becoming the norm due to the Covid-19 pandemic. The Society also wanted to maximise value from its property and generate additional revenue which could "be
reinvested into further developing our valued products and services".
Ingeus runs the government-sponsored Restart Scheme to help people find jobs in their local area.
Throughout the past decade, digital transformation has been at the forefront of the agenda for the NHS which has been accelerated by the abundance of digitally enabled ways of working during the pandemic. While the last year has unquestionably heralded the spring shoots of transformation, there is so much to be done to build upon this and accelerate further.
For example, do both pharmacists and patients comprehend the value of digital to drive change at a fundamental level? The issue is not simply ensuring that the temporary fixes inspired by the pandemic successfully transition to standard practice, but also rapidly building on that foundation to enable the greatest
value from digitisation within pharmacy.
Covid-19 has increased the need for digitally enabled and empowered ways of operating. From the backlog in outpatient appointments to postponed screening programmes and, crucially, the potential exodus of overworked and stressed pharmacists, the efficient, effective and intelligent care enabled by the right digital technologies is now critical.
The widely-held concept that levels of "good" cholesterol in the blood can indicate heart disease risk is not equally true for Blacks and whites, and the measure
itself may be of less value than previously thought, according to a U.S. study published on Monday (November 21).
Various types of cholesterol are thought to have either healthy or unhealthy effects.
Low levels of so-called "good" high-density lipoprotein (HDL) cholesterol were linked with higher odds for developing cardiac problems in the long-term study - but
only in white participants, the study published in the Journal of the American College of Cardiology found.
In contradiction to what has generally been assumed, low HDL levels did not confer any higher risk of heart disease in Black people, researchers said. Among white
people, however, those with HDL levels below 40 milligrams per deciliter had a 22% higher risk for coronary heart disease compared with those whose HDL levels were
higher.
High HDL levels (above 60 mg/dL), which are thought to be protective, were not linked with lower coronary heart disease risks in either race, researchers found.
The Pharmaceutical Services Negotiating Committee (PSNC) has announced the margin delivery rates will increase from October as the agreed £100m write off is
implemented.
"The baseline margin allowance will remain £800m per year in 2022/23 and 2023/24," said PSNC.
"Margin levels in the last two full years (2020/21 and 2021/22), as measured by the Margin Survey of independent pharmacies, were in excess of the baseline allowance,
meaning that an excess was accrued."
As new services have been introduced and take up of these has accelerated, the amount of unallocated funding left in the CPCF is now less than it previously was.
As such, the value of the Transitional Payments will decrease from its current level. Some of the unallocated funding remaining in 2023/24 will be repurposed into
a Flat Payment for all contractors (see details below).
Over the course of the second half of 2022/23, the value of the Transitional Payments will be phased down. This will start in October 2022 with a reduction in payment
levels to approximately 85% of the current level, as shown in the following table:
The Department of Health in Northern Ireland has announced an immediate intervention worth over £5.3m in value, and a commitment to progress wider reform
arrangements in collaboration with the Community Pharmacy NI (CPNI) to support pharmacies to deal with the ongoing pressure.
The Minister and Department are 'very aware of the pressures facing community pharmacies'. They discussed the situation with CPNI representatives at a meeting last
week. The scale of the unprecedented budgetary pressures and uncertainty currently facing the Department were spelt out.
The Department said: "Notwithstanding these pressures, CPNI were informed that a support package for their sector was being finalised. This package includes immediate
interventions worth over £5.3m in value, plus a commitment to progress wider reform arrangements in collaboration with CPNI."
Recently, the CPNI highlighted that community pharmacists have issued a stark warning that shortages and skyrocketing prices of many medicines could result in
pharmacies being unable to supply important prescription medicines to patients.
Amgen Inc on Monday agreed to buy Horizon Therapeutics Plc in a deal valued at $27.8 billion (£22.67bn), fortifying its rare diseases portfolio in the biggest
buyout in the sector this year.
The company will pay $116.50 in cash, a premium of nearly 20 per cent to the stock's last close, for each Horizon share.
Horizon shares closed up 15 per cent on Monday at $112.36. They had climbed 23.5 per cent through Friday since the company disclosed in late November it was in
preliminary talks with Amgen, Sanofi and Johnson & Johnson for potential offers. Amgen shares dipped less than 1 per cent to close at $276.78.
Sanofi said Sunday it ended discussions with Horizon after concluding the transaction prices "do not meet our value criteria."
J&J also said in early December that it had dropped its pursuit of the deal.
Thirteen people were arrested following raids at four drug manufacturing units in the Indian states of Gujarat and Rajasthan, resulting in the seizure of
mephedrone valued at Rs 230 crore (approximately 22.30 million GBP), according to a news agency report.
The Gujarat Anti-Terrorist Squad (ATS) and Narcotics Control Bureau conducted the raids jointly on Friday, prompted by a tip-off received by the ATS indicating
that Ahmedabad resident Manoharlal Enani and Kuldeepsinh Rajpurohit from Rajasthan had set up mephedrone manufacturing units, PTI reported on Saturday, quoting
an official.
As stated in an ATS release obtained by the news agency, the raids were conducted at the units in Sirohi and Jodhpur in Rajasthan and Piplaj village in Gandhinagar
and Bhaktinagar industrial area of Amreli district in Gujarat.
"The ATS recovered 22.028 kilograms of mephedrone (in solid form) and 124 kilograms of liquid mephedrone, collectively valued at Rs 230 crore(approximately
22.30 million GBP).
"Rajpurohit was nabbed during the raid in Gandhinagar and Enani was held from Sirohi," it said.
Darren Jones MP, the Shadow Chief Secretary to the Treasury, visited Sigma Pharmaceuticals plc's new Watford facility on Thursday (6 June) as part of the
imminent Labour Party campaign trail.
Jones was joined by Labour's prospective parliamentary candidate for Watford, Matt Turmaine, and a team of campaign workers.
During their visit, the Labour delegation met with the directors and founding member of Sigma, Dr Bharat Shah CBE, and discussed the importance of investment
and support for growing businesses and the pharmaceutical sector both in the region and across the country.
Sigma Pharmaceuticals, which is believed to be Watford's largest employer, noted that the pharmaceutical sector contributes a significant value to the East of
England, accounting for 12.3 per cent of the region's manufacturing gross value added (GVA).
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