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Pharmanovia, the lifecycle management company has signed a licence and supply agreement with Aquestive Therapeutics for its patented diazepam buccal film formulation across the EU, UK, Switzerland, and Norway, as well as countries in the Middle East and North Africa (MENA)- up to 48 markets in total. Aquestive Therapeutics has been granted tentative approval by the US Food and Drug Administration (FDA), for its diazepam buccal film for the acute treatment of intermittent, stereotypic episodes of frequent seizure activity (i.e., seizure clusters, acute repetitive seizures) that are distinct from a patient's usual seizure pattern in patients with epilepsy 12 years of age and older. Pharmanovia will be responsible for seeking appropriate regulatory approval across EU and MENA. Pharmanovia CEO, James Burt commented: "Pharmanovia and Aquestive are aligned in our mission to find new and innovative ways to enhance and revitalise iconic medicines. We have extensive experience with diazepam through the Valium brand and, together with Aquestive's unique PharmFilm technology, we're intending to bring a novel alternative diazepam delivery option to caregivers and patients at a time of critical need."

Esperion Therapeutics' non-statin therapy "bempedoic acid" has shown modest results in reducing the risk of major cardiovascular events in statin-intolerant patients in the cholesterol lowering via bempedoic acid, an ACL-inhibiting regimen (CLEAR Outcomes) trial, revealed GlobalData, a leading data and analytics company. As a result, there is substantial room for improvement in this space as a potential approval is expected in Australia in near-term based on these results, said GlobalData. According to GlobalData's Pharmaceutical Intelligence Center, the total number of diagnosed prevalent cases of dyslipidemia in Australia is expected to increase at a compound annual growth rate of approximately 1.2% from 5.2 million in 2022 to 5.4 million in 2025. Neha Myneni, Pharma Analyst at GlobalData, comments: "Bempedoic acid joins several statin alternatives that have shown the potential to reduce cardiac illnesses. However, with not much significant improvement in the outcomes, there exists a clear room for improvement for non-statin therapies in this space." Bempedoic acid is the sixth class of cholesterol-lowering drugs (other than cholesteryl-ester transfer protein isoform (CETPi) inhibitors), that has demonstrated the potential to reduce heart attacks and strokes. Other class of therapies with similar potential currently marketed in Australia include statins, bile acid resins, niacin, ezetimibe, and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors (alirocumab, evolocumab, and inclisiran).

In a recent announcement, Mundipharma, a leading global pharmaceutical company, has announced its acquisition of all assets and rights related to rezafungin from Cidara Therapeutics. This solidified Mundipharma's dedication to managing infectious diseases and specialty care therapeutic areas, especially invasisve candidiasis which over the 15 years has seen no new therapeutic developments underscoring for alternative options. The FDA and MHRA approved rezafungin is a groundbreaking once-weekly echinocandin antifungal drug specifically designed for the treatment of invasive candidiasis in adults. While Mundipharma will oversee global commercialization efforts, Melinta Therapeutics will retain commercialization rights for rezafungin in the United States. Moreover, the acquisition empowers the pharmaceutical company with global ownership of rezafungin, encompassing its ongoing development and distribution.

Infoholic's market research report predicts that the global leukemia therapeutics market will grow at a CAGR of 6.2% during the forecast period 2019-2025. Leukemia refers to the group of blood cancer that usually develops in the bone marrow, resulting in the formation of abnormal blood cells. Leukemia is subdivided into lymphoblastic or lymphocytic leukemias and myeloid or myelogenous leukemias that include acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic lymphocytic leukemia (CLL), and chronic myeloid leukemia (CML). The report provides complete details about the sub-segment of the global leukemia therapeutics market. Moreover, the report provides details about the major challenges that are going to impact the market growth. Additionally, the report gives complete details about the key business opportunities to key stakeholders in order to expand their business and capture the revenue in specific verticals, and to analyze before investing or expanding the business in this market.

The global digital therapeutics market size is anticipated to reach USD 19.1 billion by 2028, according to a new report

Global pharmaceutical and biotechnology company AstraZeneca has signed an agreement with Scorpion Therapeutics to discover, develop and commercialize precision medicines against cancer proteins. The collaboration, announced today (January 13), will focus on a class of proteins called transcription factors, which can regulate important cellular processes including cell growth and survival. Many transcription factors have been identified earlier, but were considered 'undruggable' using conventional drug discovery approaches, the company said in a statement. Susan Galbraith, executive vice president, Oncology R&D, AstraZeneca, said: "Unlocking potentially transformative biology is pivotal for delivering the next wave of cancer treatments. "Scorpion's innovative platform is a strong strategic fit as we explore a range of new modalities across our broad drug discovery toolbox with promise to disrupt the activity of these highly-validated cancer targets."

Capitalising on strong demand for its obesity therapies, Novo Nordisk's growing appetite for deals has fuelled a bet on a U.S. gene-editing company called Life Edit Therapeutics. The Danish drugmaker's collaboration with Durham, North Carolina-based Life Edit Therapeutics - owned by ElevateBio, a cell and gene therapy company in Waltham - is focused on up to seven programs for rare genetic disorders as well as cardiometabolic diseases. At the heart of the tie-up is Life Edit's technology, called base editing, which is designed to make precise changes to the human genome by tweaking one base - or letter - into a different one without affecting other letters. Single-letter mistakes, called point mutations, can give rise to genetic diseases.

Amgen Inc on Monday agreed to buy Horizon Therapeutics Plc in a deal valued at $27.8 billion (£22.67bn), fortifying its rare diseases portfolio in the biggest buyout in the sector this year. The company will pay $116.50 in cash, a premium of nearly 20 per cent to the stock's last close, for each Horizon share. Horizon shares closed up 15 per cent on Monday at $112.36. They had climbed 23.5 per cent through Friday since the company disclosed in late November it was in preliminary talks with Amgen, Sanofi and Johnson & Johnson for potential offers. Amgen shares dipped less than 1 per cent to close at $276.78. Sanofi said Sunday it ended discussions with Horizon after concluding the transaction prices "do not meet our value criteria." J&J also said in early December that it had dropped its pursuit of the deal.

We cannot deny the benefits and uses of regenerative medicines as they have been so in demand in recent times. One such effective medicine with a lot of potential health benefits is BPS-157. The peptide is thought to be extremely beneficial for those struggling with various neurological or health issues. Another medicine with the same beneficial effects is the Semax peptide. Well, the benefits of both these peptide-based medicines and their other aspects will be discussed in detail in this blog along with answering your question about the BPC-157 buy, Semax effects, and polypeptide. ALL ABOUT BPC-157: BPC-157, a pentadecapeptide consisting of 15 amino acids, is a synthetic peptide that is known for its positive effects on the human body. The peptide is derived from human gastric juice. A protein is present in the human gastric juice through which this peptide is derived and synthesized. It is called a Body Protection Protein as it exerts several therapeutic effects on the human body. Not only have health benefits or therapeutic effects, the peptide has healing and regeneration powers. It also helps in the preventing formation of gastric ulcers. This peptide is of great interest to researchers due to its numerous positive effects and benefits. DOSING LEVELS OF BPC-157: Not much about the dosing levels of BPC-157 has been researched yet but always try to concern the relevant persons before taking the medicine. The dosage of BPC-157 depends on the health and body conditions of the person taking it along with other related factors.

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Oquprime is a clinically-proven natural remedy that significantly improves visual acuity and protects eyesight when engaging in visually demanding activities like staring at a computer screen. This is made possible by the unique qualities of the bioactive chemicals included in their compositions.

The main reason for this is the major improvements in the methods for processing the organic materials utilized to create the therapeutic formulations of Oquprime.

Ginger is an age-old herb that has had extensive usage in history for its numerous natural therapeutic effects, especially as an "anti-emetic." The best-known proof indicates that ginger is an effective and affordable remedy for nauseatic and vomiting ailments and is safe. The pleasing zesty "kick" from the root of Zingiber officinale, the ginger plant, is what produces ginger ale, ginger tea, sweets, loaves of bread, and many Asian dishes so delicious. Ginger adds an aromatic tang to both sweet and spicy foods. As ginger is frequently suggested for its stomach-settling impacts, you may wonder whether it's a proven way to treat nauseatic ailments naturally. This article reevaluates the efficacy and safety of ginger for nausea and the most promising practices for using it. How does Ginger Help with Nausea? According to PubMed Central, the highly appreciated database from the National Institutes of Health, it's believed that ginger fetches its therapeutic qualities from gingerol, the main bioactive ingredient in fresh ginger, and complementary blends called shogaols, which provide the root its savory flavor. Shogaols are more robust in dried ginger, with 6-shogaol as the primary source of antioxidants. At the same time, gingerols are more plentiful in raw ginger. Some examination has revealed that ginger and its compounds may improve digestive function and speed up stomach emptying feel, relieving nausea. Its anti-inflammatory traits may improve digestive activity and sustain the discharge of blood-pressure-regulating hormones to relax your body and ease nausea. Other Health Benefits of Ginger Being an anti-inflammatory, antioxidant, and digestive aid, it has been used as a natural treatment for helping to alleviate nausea and other symptoms. It can be used to treat: Heartburn Indigestion Motion sickness Reduce joint pain Soothe sore throats Minimize the duration of colds and flu viruses Ease menstrual cramps Prevent cancer cell growth Improve choleste

Integrative Cancer Science and Therapeutics welcomes submission of papers both at the molecular, subcellular, cellular, organ, and organism level, and of clinical proof-of-concept and translational studies. Topics of interest include, but are not limited to: novel basic cancer research discoveries, cell and tumor biology, animal models, metastasis, cancer antigens and the immune response to them, cellular signalling and molecular biology, epidemiology, genetic and molecular profiling of cancer and molecular targets, cancer stem cells, cancer-associated pathways (including cell-cycle regulation; cell death; chromatin regulation; DNA damage and repair; gene and RNA regulation; genomics; oncogenes and tumor suppressors; and signal transduction), molecular virology and vaccine- and antibody-based cancer therapies, and other cancer-related research.

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MabVax Therapeutics and Telik sign definitive merger agreement

Thigh Support Applications Mild support to quadriceps and hamstrings. Relieves inflammation and stiffness. Firm compression and therapeutic warmth. Psychological support to geriatric patients. Sports injury, sprains and strains. Post-surgical rehabilitation. Burn care. Thigh Support Features Strong Compression. Four way stretch. Dermophillic. Durable. Breathable and comfortable. Thigh Support Measurements Measure circumference around mid thigh - approximately 6 inches above knee. Size Chart - Size Inches CM Small 14.8 to 17.2 37 to 43 Medium 17.2 to 19.6 43 to 49 Large 19.6 to 22.0 49 to 55

mmunе system boosters and immunomodulators are major therapeutic agents used to treat hepatitis, herpes, cancer. Therefore they should not be used to boost the immune system, and to be appointed by the specialist after a careful review. One of the functions of the immune system is to regulate cell growth, that prevent viral and bacterial diseases. Therefore, not all well evaluated using immunomodulatory agents may cause "immune error" and cause serious health problems (e.g., unlocking the autoimmune disease).

Vissco Elastic Knee Support Muscle or Ligament strains can be really bothersome, especially at the knee joint. We often over-work our knees in strenuous physical activities and then suffer from inflammations or strains. It's always good to pick up an elastic knee support. It provides compression, warmth and improves blood flow to the soft tissue areas surrounding the joint. Three Velcro straps allow for an optimal and comfortable fit. Its lightweight, breathable and comfortable ensuring it's worn more often, thus improving its therapeutic results. The cotton knitted fabric releases sweat and permit airflow, which its ergonomic design ensures a two way stretch. WHEN TO USE Post-surgery Muscle and Ligament Strains Soft tissue discomfort (e.g. tendomyopathies) insertion tendinitis mild effusions or swellings. Vissco Elastic Knee Support Features Skin Friendly Easy Breathe Soft Support 4 Way Stretch Anti-Fungal

Check out Ryan's review of the Eardoc, and see how big his smile is when he talks about the Eardoc. The Eardoc is a therapeutic device treating ear infections and ear pain. Most ear infections are caused by fluids trapped in the middle ear, causing pain and providing a great environment for bacteria growth.