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Germany's Boehringer Ingelheim said on Thursday (Aug 17) it would conduct three late-stage studies for its obesity drug candidate after it showed up to 19 per cent weight loss after 46 weeks in a mid-stage trial. The private company plans to start enrollments for the trial of the drug, survodutide, which it co-invented with Danish biotech company Zealand Pharma, before the end of the year. The trials will evaluate the drug's safety and efficacy, Boehringer said, and added that it would provide further details on the studies before initiation. Boehringer and Zealand are among global drugmakers racing to grab a share of the potential $100 billion market for obesity treatments within a decade. Survodutide works by mimicking a gut hormone called glucagon-like peptide-1 (GLP-1), which suppresses appetite, as well as imitating another gut hormone called glucagon that helps break down fat.

More than 7,000 hospitalisations and deaths in the UK could have been averted in summer 2022 if people had received their recommended COVID-19 vaccine doses, a new study published in The Lancet has revealed. The largest ever study carried out in the UK found that between a third and a half of the UK population had not had the recommended number of COVID vaccinations and boosters by summer 2022. In Northern Ireland, nearly 50 per cent of the population were under-vaccinated, while the proportion of under-vaccinated people in England was 45.7 per cent, 34.2 per cent for Scotland and 32.8 per cent Wales. Researchers from the Health Data Research UK (HDR UK) and the University of Edinburgh analysed the electronic health records of 67 million residents aged 5 and older from across the four countries during June 1 to September 30 2022.

A health care administration degree provides the skills and knowledge that you require to help ensure that your organization has strong  management and administration.  This page gives you more information about what is involved in studying online masters and PhDs in health care administration, where you can study them, and the job and salary prospects after completion.

A new study finding suggests that consuming sugar can actually pave way to cancer growth. Research journal corroborate other study findings that indicate People with excess sugar intake face increased risks of cancer.

In a University of Chicago study of overweight adults following a balanced, restricted-calorie diet, subjects lost 55 percent more weight as fat (almost two pounds) after two weeks when they slept for 8.5 hours each night compared with a period of sleeping only 5.5 hours. When you're short on shut-eye, study authors say, your body produces more ghrelin, one of the hunger hormones.

Health Study Weekly - an online newspaper that collects together the week's news relating to health education. Read and subscribe free of charge at:  http://paper.li/f-1327779598

An online newspaper that collects together the week's news relating to health education.Read and subscribe free at: http://paper.li/f-1327779598

While this study offers a slice of hope for victims, the further research is required. According to researchers, because of the potential treatments' anti-tumoral results, advances in therapy treatment may be further explored.

Fruitless diet programs are often a psychological-not physiological-problem. Many diet programs are potentially effective but fail to produce immediate results, causing disheartened dieters to abandon an otherwise rewarding path. Substitute quick, robust losses, and dieters experience optimism rather than demotivation and enjoy continued progress rather than resignation. Nutrition expert and personal trainer Brian Flatt recognized this pattern and created The 2 Week Diet, a new weight loss program that flips the conventional psychology on its head to great effect. Users typically report losing 8-16 pounds in 14 days. "Nothing breeds success like success," said Flatt, who also owns R.E.V. Fitness in Southern California. "Now dieters can see their progress almost immediately, so instead of growing discouraged and bouncing from program to program, they devote sustained energy to their current diet plan." The notion that early success generates more success has been substantiated in a recent study by Arnout van de Rijt, Associate Professor in Stony Brook University's Department of Sociology and the Institute for Advanced Computational Science (IACS). He concluded, "Modest initial success may be sufficient to trigger a self-propelling cascade of success in various success-breeds-success scenarios." Flatt applies this wisdom to his system, "When a dieter sees quick results, he or she becomes more engaged. That produces a 'snowball effect': results get better and better as dieters see themselves getting leaner and leaner." On this program, dieters notice favorable body composition changes in the first couple of days. In the first week alone, dieters are likely to see in the neighborhood of 10 pounds of fat stripped from their body. Flatt exults, "Their clothes will be looser, they will feel lighter, and they'll feel 10 times better." His program does much more to help dieters lose as much weight as possible. It corrects the

This research study involves the extensive usage of secondary sources, directories, and databases (such as Bloomberg Business and Factiva), to identify and collect information useful for this technical, market-oriented, and financial study of the cold pain therapy market. In-depth interviews were conducted with various primary respondents, including subject-matter experts (SMEs), C-level executives of key market players, and industry consultants to obtain and verify qualitative and quantitative information and to assess market prospects.

Apple has joined forces with Eli Lilly and Evidation Health on a new feasibility study to detect evidence of brain decline with data from personal digital devices. The research has revealed that these devices may help in the identification of mild cognitive impairment (MCI) and Alzheimer's disease dementia.

A new study has revealed that public trust in services provided by local pharmacies ranks highest in the UK, although confidence in the NHS has nosedived following the pandemic. The 2022 Edelman Trust Barometer report published on Wednesday (April 21) found that around 78 per cent of respondents trust their local pharmacies, the highest for any provider cited in the survey. Besides, 72 per cent said pharmacists are among the most trusted to tell the truth about health matters and protect public health, almost similar to 'my doctor' (75%) and health experts (74%). Just under half of them said the pandemic has decreased their confidence that the NHS is well-equipped in handling major health crisis. The survey also revealed that 60 per cent think they lack access to high-quality healthcare.

The NHS plans to train hundreds of pharmacy staff, expanding their ability to provide advanced clinical services and assume wider roles in dispensing medicines. With a targeted launch in September, up to 840 pharmacy technicians can join in the training programme. The online modules will cover consultation skills, therapeutics, clinical decision-making, assessment skills, and service improvement. "Community pharmacies are pivotal in local communities, and this novel training scheme empowers them to extend their service offerings to a wider patient base," said Health Minister Neil O'Brien. "Through our investment in the workforce, we're bolstering the implementation of the Pharmacy First initiative with £645 million, ensuring patients have access to expert assistance for various common ailments, including urinary tract infections and earaches." NHS said the training will offer flexibility to align with the working schedules and prior experience of community pharmacy technicians. It will combine independent online e-course study, educational supervision, and clinical skills training. Facilitated workshops will concentrate on enhancing clinical assessment skills and applying knowledge and skills through case studies, practice activities, and group discussions.

Eighty-one per cent of the National Pharmacy Association cohort of trainee pharmacists passed the General Pharmaceutical Council (GPhC)'s common registration assessment which took place in June. The NPA's team of learning and development pharmacists helped students prepare for the assessment with study days and mock exams. Celebrating the success of trainee pharmacists, it said: "The 81 per cent NPA pass rate reflected the comprehensive blended learning experience delivered by the NPA's team of learning and development pharmacists and that we were able to resume face-to-face study days for this cohort after the restrictions of lockdowns." Last month, the GPhC and Pharmaceutical Society of Northern Ireland (PSNI) published result of the common registration assessment for pharmacists with an overall pass rate of 80 per cent. A total of 2,697 candidates sat the registration assessment in four countries on 29 June and 2,147 candidates passed the assessment.

A new study by the University of East Anglia has found that giving out 'vape starter kit vouchers' on the NHS could help even hardened smokers quit. In the recent study, researchers worked with GPs and the 'NHS stop smoking service', commissioned locally by Public Health at Norfolk County Council, to set up a pilot 'vape shop voucher' scheme (worth £25 each) to help patients who had tried but failed to stub it out in the past. An evaluation of the scheme, funded by Norfolk County Council, showed it was a big success - with 42 per cent of the entrenched smokers who were referred to it and redeemed their vape voucher having quit within a month. After the success of the pilot, the scheme has been rolled out across Norfolk and the research team hope it could be rolled out nationally to help more smokers quit. Lead researcher and addiction expert Prof Caitlin Notley, from the UEA's Norwich Medical School, said: "Research shows that vaping is an effective way of quitting smoking, compared to nicotine replacement therapies like patches and gum. E-cigarettes or vapes are now the most popular way of stopping smoking.

The Scottish Medicines Consortium (SMC) has accepted AbbVie's RINVOQ (upadacitinib) for use within NHS Scotland for the treatment of adult patients with moderately to severely active ulcerative colitis (UC). Upadacitinib offers an additional treatment choice in the therapeutic class of janus kinase inhibitors. "Daily life with ulcerative colitis is difficult due to the debilitating and unpredictable nature of its symptoms", said Dr Jonathan Macdonald, Consultant Gastroenterologist at NHS Greater Glasgow and Clyde. "Clinical trials have shown that upadacitinib as a once daily pill controls symptoms in eight weeks for many patients and provided sustained responses at one year. The SMC's decision is good news for people with ulcerative colitis in Scotland as it provides an additional treatment option to help them gain control of their condition." The SMC decision is based on data from the induction studies U-ACHIEVE and U-ACCOMPLISH, as well as the Phase 3 U-ACHIEVE maintenance study, which demonstrated the efficacy of upadacitinib versus placebo in its ability to achieve clinical remission. The SMC's decision follows the granting of Marketing Authorisation for upadacitinib in UC in July 2022.

Pfizer said on Thursday (June 1) data from late-stage trials showed its experimental combination of antibiotics was effective in treating deadly infections caused by drug-resistant bacteria. Deaths from antibiotic-resistant bacteria, also known as superbugs, have been on the rise globally, and health regulators have called for the development of newer treatments as resistance to older antibiotics grows. The late-stage studies compared the experimental combination of the antibiotics aztreonam-avibactam (ATM-AVI) and existing generic drug metronidazole with a combination of two older antibiotics - meropenem and colistin - to treat complicated intra-abdominal infections and types of hospital-acquired pneumonia. Hospital-acquired pneumonia occurs in patients at least two to three days after being admitted, or in those who have life-threatening lung infections with high mortality rates and who are on mechanical breathing machines. Pfizer said the data from the studies shows the antibiotic combination of ATM-AVI is effective and well-tolerated in treating infections caused by gram-negative bacteria. The cure rate in patients with complicated intra-abdominal infections with Pfizer's combination therapy, along with existing generic drug metronidazole, was 76.4%, versus 74% using the other antibiotics.

An experimental Alzheimer's drug developed by Eli Lilly and Co slowed cognitive decline by 35% in a late-stage trial, the company said on Wednesday, providing what experts say is the strongest evidence yet that removing sticky amyloid plaques from the brain benefits patients with the fatal disease. Lilly's drug, donanemab, met all goals of the trial, the company said. It slowed progression of Alzheimer's by 35% compared to a placebo in 1,182 people with early-stage disease whose brains had deposits of two key Alzheimer's proteins, beta amyloid as well as intermediate levels of tau, a protein linked with disease progression and brain cell death. The study also evaluated the drug in 552 patients with high levels of tau and found that when both groups were combined, donanemab slowed progression by 29% based on a commonly used scale of dementia progression known as the Clinical Dementia Rating Scale (CDR-SB). Using that scale, experts said Lilly's findings were roughly on par with Eisai Co Ltd and Biogen Inc's lecanemab, sold under the brand name Leqembi, which reduced cognitive decline by 27% in patients with early Alzheimer's in a study published last year. The results drove Lilly's shares to a record high, up more than 6% at $429.85. Dr. Ronald Petersen, an Alzheimer's researcher at Mayo Clinic, said Lilly's trial is the third to show removing amyloid from the brain slows progression of the disease, which could put to rest some lingering doubts about the benefits of drugs in the class and the amyloid-lowering theory. "It's modest, but I think it's real," he said of the benefit, "and I think it's clinically meaningful." Dr. Erik Musiek, a Washington University neurologist at Barnes-Jewish Hospital, said the efficacy looks as good or better than lecanemab.