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An experimental Alzheimer's drug developed by Eli Lilly and Co slowed cognitive decline by 35% in a late-stage trial, the company said on Wednesday, providing what experts say is the strongest evidence yet that removing sticky amyloid plaques from the brain benefits patients with the fatal disease. Lilly's drug, donanemab, met all goals of the trial, the company said. It slowed progression of Alzheimer's by 35% compared to a placebo in 1,182 people with early-stage disease whose brains had deposits of two key Alzheimer's proteins, beta amyloid as well as intermediate levels of tau, a protein linked with disease progression and brain cell death. The study also evaluated the drug in 552 patients with high levels of tau and found that when both groups were combined, donanemab slowed progression by 29% based on a commonly used scale of dementia progression known as the Clinical Dementia Rating Scale (CDR-SB). Using that scale, experts said Lilly's findings were roughly on par with Eisai Co Ltd and Biogen Inc's lecanemab, sold under the brand name Leqembi, which reduced cognitive decline by 27% in patients with early Alzheimer's in a study published last year. The results drove Lilly's shares to a record high, up more than 6% at $429.85. Dr. Ronald Petersen, an Alzheimer's researcher at Mayo Clinic, said Lilly's trial is the third to show removing amyloid from the brain slows progression of the disease, which could put to rest some lingering doubts about the benefits of drugs in the class and the amyloid-lowering theory. "It's modest, but I think it's real," he said of the benefit, "and I think it's clinically meaningful." Dr. Erik Musiek, a Washington University neurologist at Barnes-Jewish Hospital, said the efficacy looks as good or better than lecanemab.

Early detection and treatment of Alzheimer's disease require the use of dependable and cost-effective screening technologies. Researchers at Sweden's Karolinska Institutet have revealed that the level of tau, a protein that plays a vital role in the development of severe dementia, is associated with a kind of sugar molecule in the blood. The study, which is published in Alzheimer's & Dementia, can pave the way for a simple screening procedure able to predict onset ten years in advance. "The role of glycans, structures made up of sugar molecules, is a relatively unexplored field in dementia research," says the study's first author Robin Zhou, medical student and affiliated researcher at the Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet. "We demonstrate in our study that blood levels of glycans are altered early during the development of the disease. This could mean that we'll be able to predict the risk of Alzheimer's disease with only a blood test and a memory test." In Alzheimer's disease, the neurons of the brain die, which is thought to be a result of the abnormal accumulation of the proteins amyloid beta and tau. Clinical trials for Alzheimer's drugs show that treatment should commence early in the pathological process, before too many neurons have died, to reverse the process before it is too late.

A new research has suggested that meat contributes to the growing global obesity prevalence as much as sugar and moreover it is protein, not the fat present in meat which is a major obesity contributor. Proteins digest slow as compared to fats Carbohydrates and fats not only provide us with enough energy, the body demands, they are also digested faster than protein.

The current trend is all about eating vegetarian food and avoiding meat. Many people have the misconception that fresh fruits and vegetables can suffice the nutritional needs and that plant proteins are better than animal protein. But then, meat recipes comprise of larger amount of proteins that you cannot attain from plants.

The main cause of hair loss in the female is hormonal and genetic. Other causes are various vitamin, nutrient, protein and iron deficiency. Females usually ignore about their diet and often takes meals at long interval reason they take care of entire family and do not pay attention to themselves. So poor diet, stress, and hormones abnormalities are the most common cause of hair loss in females.

The main cause of hair loss in the female is hormonal and genetic. Other causes are various vitamin, nutrient, protein and iron deficiency. Females usually ignore about their diet and often takes meals at long interval reason they take care of entire family and do not pay attention to themselves. So poor diet, stress, and hormones abnormalities are the most common cause of hair loss in females.

It is highly recommended to include hemp seed protein powder or hemp seed oil in your daily diet from cannaessentials-the largest online marketplace of hemp goods.

The Keto diet is one of the most popular diets in the world at the moment and for good reason. This low carb high in good fats diet helps the body burn stored fat through a process called "ketosis", hence the name. The key to success is sticking with the diet because when you slip up, your body slips out of the ketosis state you've put it in. When it comes to sweet goodies this can be a little bit difficult. However, it doesn't have to be! Here are 6 smoothie combinations for you to try playing around with that will feel like you're cheating on your diet but are perfectly keto-friendly. 1. COCONUT CHOCOLATE DELIGHT Coconut is one of the best ingredients for a keto smoothie. It has those good fats your body needs in order for it to stay in ketosis. It tastes pretty good, but what tastes better than coconut? That's right - chocolate. Chocolate and coconut are a smoothie match made in heaven and can be used to make a Keto smoothie bowl recipe that acts as an alternative to chocolate pudding. The coconut gives the mixture a really smooth and creamy consistency and using cocoa powder is a really healthy way to get your chocolate fix for the day. If you want to be extra healthy, you can substitute the cocoa powder with a chocolate protein powder.

Scientists Katalin Kariko and Drew Weissman from Hungary and the United States respectively won the 2023 Nobel Prize in Physiology or Medicine for discoveries enabling the development of mRNA COVID-19 vaccines, the award-giving body said on Monday. The prize, among the most prestigious in the scientific world, is selected by the Nobel Assembly of Sweden's Karolinska Institute medical university and also comes with 11 million Swedish crowns (about £823,500). "The 2023 Nobel Prize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19," the body said. Kariko was senior vice president and head of RNA protein replacement at BioNTech until 2022 and has since acted as an adviser to the company. She is also a professor at the University of Szeged in Hungary and adjunct professor at the University of Pennsylvania's Perelman School of Medicine. Weissman is professor in vaccine research at the Perelman School.

Sau khi phá an toàn cơ thể của người bệnh sẽ thường trở nên yếu hơn do bị mất một lượng máu nhất định chính vì thế trong lúc này cơ thể cần được cung cấp protein, vitamin và muối vô cơ

US-based BioMarin Pharmaceutical has selected a new drug development candidate, BMN 250, for the treatment of Sanfilippo B syndrome or Mucopolysaccharidosis type IIIB (MPS IIIB).

In order to enable the immune system to function normally, the body needs: protein necessary for the construction of the immune cells and antibodies, carbohydrates for energy, which without any physiological process in the body is not possible, is also necessary for the fat metabolism, minerals and vitamins included in the composition of enzymes, which are due to perform and provide conversion processes. - See more at: http://www.immunesystemboosters.info/2013/08/which-vitamins-mostly-boost-immune.html#sthash.HRijemgv.dpuf

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It is possible to associate tumor development with immune complement, providing new molecular targets for drug therapy. To this end, small Interference RNA Knockdown is constructed. Western blot shows that siRNA can effectively reduce the expression of CCP22 protein.

How to strengthen the child's immune system? 1.The first is a healthy diet which strengthens the immune system and makes them function properly . In low- protein meals decreased the number of active T cells and macrophages , as well as reducing the formation of immunoglobulin A (IgA), which are the " agents" of the immune system. Raw fruits and vegetables are the best source of vitamins and minerals to the body. No child who does not like fruit. Moreover, they are naturally sweet and are a great alternative for breakfast. You can also offer them raw or passion in the form of paste, if little boy prefers them so .

The first and most shocking secret is that the last 10 to 20 pounds that seems so tough to loose, especially fat around the belly, thighs and bottom, just might be saving your life.

After going through a surgery of the prostate gland, it is found that up to 80% of people lose their efficiency to attain erection at the time of performing sex. This is because at the time of the removal of the gland, there is a harm done to the thin nerve that runs along the prostate gland.

SkinMedica skincare products are formulated with scientifically proven recovery compounds including essential ingredients ranging from vitamins C & E to retinol to TNS (Tissue Nutrient Solution), a patented blend of growth factors, soluble collagen, antioxidants and matrix proteins.

You need to know some facts about milk which can be helpful for your health.Most importantly milk is so much balanced having many number of nutrients. 1.Many nutritional components in milk such as Carbohydrate,Proteins,Vitamins,Minerals,Fats etc. 2.The protein and carbohydrate of milk gives us so much energy.

Các bác sỹ chuyên khoa cho biết, khi bị yếu sinh lý, một phần nguyên nhân quan trọng là do sức khỏe của nam giới bị suy giảm, ảnh hưởng từ nhiều yếu tố trong đó có chế độ ăn uống, sinh hoạt. Vì thế, nam giới khi bị yếu sinh lý nếu có một chế độ ăn uống hợp lý, khoa học sẽ hỗ trợ tích cực cho việc nâng cao sức khỏe, chức năng sinh lý phái mạnh. Sau đây là một số loại thực phẩm hữu ích mà nam giới bị yếu sinh lý nên bổ sung: - Hải sản: có chứa nhiều kẽm - một loại chất tham gia vào rất nhiều quá trình xử lý của cơ thể, có tác dụng chống lại nguy cơ ung thư tuyến tiền liệt, gia tăng chất lượng và số lượng tinh trùng, đặc biệt là hàu, ngao, tôm, cua… rất tốt cho sức khỏe và sinh lý nam giới. - Các loại thịt đỏ: giàu protein và các dưỡng chất cần thiết cho cơ thể, giúp tăng cường sinh lực;