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A daily medication for high blood pressure could be replaced by an injection twice a year, if Queen Mary University and Barts Health NHS Trust succeed in their trail to investigate if an injection-based drug - Zilebesiran - could inhibit the production of a protein called angiotensinogen (AGT). Scientists are to trial a world-first drug to treat high blood pressure that can be given by injection twice a year. Professor Sir Nilesh Samani, medical director, British Heart Foundation, said: "This exciting trial could lead to good news for the millions of people across the UK with high blood pressure, many of whom need to take daily medication to lower their risk of heart attacks and strokes. "The study will determine whether an injection given twice a year lowers blood pressure sufficiently over a prolonged period. "If this proves to be the case, it may provide an alternative to taking daily pills for some patients."

A study by scientists in a UK university has shown the scale of the prevalence of a condition that can lead to various cardiometabolic diseases. The study published in the Annals of Internal Medicine journal on Tuesday (January 4) has prompted calls for changes to healthcare policy after researchers revealed, for the first time, the scale of the impact of the condition associated with benign tumours that can lead to type 2 diabetes and high blood pressure. Up to 10 per cent of adults have a benign tumour, or lump, known as an 'adrenal incidentaloma' in their adrenal glands which can be associated with the overproduction of hormones including the stress steroid hormone cortisol that can lead to type 2 diabetes and high blood pressure. Previous small studies suggested that one in three adrenal incidentalomas produce excess cortisol, a condition called mild autonomous cortisol secretion (MACS). An international research team led by the University of Birmingham carried out the largest ever prospective study of over 1,305 patients with adrenal incidentalomas to assess their risk of high blood pressure and type 2 diabetes and their cortisol production by comparing patients with and without MACS.

A change in medication can benefit patients on blood pressure-lowering therapies significantly more than increasing the dose of their current medication. A recent study from Uppsala University that was published in the Journal of the American Medical Association (JAMA) demonstrates this. In this study, four different blood pressure-lowering medications were tested out on 280 individuals over the course of a year. "The effect of a change of medication can be twice as great as the effect of doubling the dose of the patient's current medication. It was clear in our study that certain patients achieved lower blood pressure from one drug than from another. This effect is large enough to be clinically relevant," said Johan Sundstrom, cardiologist and Professor of Epidemiology at Uppsala University, who is the first author of the study. Most Swedes develop high blood pressure sooner or later; more than two million Swedes have high blood pressure at the present time. Only a fifth of them have managed to bring their blood pressure under control through drug therapy, and some studies suggest that only half of them take their blood pressure medication as intended. Could this be because the efficacy and side-effects of the drugs differ from individual to individual?

High levels of blood pressure lead to a number of problems in a man's life. The most disastrous among them is the havoc it creates in a man's sexual life. High levels of BP have the capability of reducing the strength of a person to have any physical activity leave alone sexual intercourse.

Well Pharmacy is offering free blood pressure checks in all its branches across England to raise awareness of the dangers posed by hypertension. The leading independent pharmacy chain is inviting people to #thebigsqueeze in conjunction with May Measurement Month and World Hypertension Day (May 17) by inviting them to get a free blood pressure check and to learn more on the importance of understanding hypertension. George Sandhu, deputy superintendent pharmacist at Well Pharmacy said: "May Measurement Month is a global blood pressure screening awareness campaign. The aim is to raise awareness of the dangers posed by elevated BP and hypertension. May 17 is World Hypertension Day, and a perfect time to take control and get your blood pressure checked. "We are delighted to be supporting this campaign. Hypertension (more commonly known as high blood pressure) can cause a range of health issues.  Worryingly, it often comes with no symptoms, which is why it is vital to know if your blood pressure is higher people don't have any symptoms of high blood pressure so having their blood pressure checked is the only way to find out. "People can come into any of our Well Pharmacies across England and have their blood pressure checked. The theme for 2023 is Measure Your Blood Pressure Accurately, Control It, Live Longer - and knowing your number is one of the most important things people can do.

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Gastroesophageal Reflux Disease (GERD) also called acid regurgitation or gastroesophageal reflux, is a digestive disorder that occurs when acidic stomach juices or food travels back up from the stomach into the oesophagus. Read more about GERD by Fostr multispeciality hospital, Bangalore