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Patient monitoring refers to the collection and analysis of medical data from one or more health settings (such as in hospitals or doctor's offices) for use by health care providers and other professionals in order to detect changes in an individual's medical status and to provide treatment options as needed. In health care, patient monitoring is generally the measurement of one or more medical parameters over extended periods of time, usually at different health care settings (such as in doctor's offices or hospitals). Patient monitoring may be implemented in many different health care settings including primary care offices, emergency rooms, doctors' offices, nursing homes, private practices, and government agencies. Most patient monitoring systems contain software that collect and store medical data in a database that is accessible to multiple health care providers and to health care facilities. High prevalence of chronic disorders is expected to propel growth of the global remote patient monitoring devices market over the forecast period. For instance, according to the study, "Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition", published in the journal Diabetes Research and Clinical Practice, in September 2019, 463 million people are expected to suffer from diabetes in 2019 worldwide and the number is expected to reach 578 million by 2030 and 700 million by 2045. Read More @ https://coherentmarketinsights-blog.blogspot.com/2020/11/high-prevalence-of-chronic-disorders-to.html

Advanced Therapy Medicinal Products (ATMPs) offer a real and tangible hope for many different chronic illnesses for which there currently are no or limited therapeutic options. The science and technology that support these products are developing rapidly and therefore the products that are on the market today will undoubtedly continue to improve and grow in effectiveness and capability over time. Patients around the world are now beginning to experience the benefits of these improved products. One such product is Stem Cell Therapy, which uses stem cells from healthy cells taken from the patient's own body. High prevalence of Alzheimer's disease is expected to propel growth of the advanced therapy medicinal products market. For instance, According to the data from Alzheimer's Association, around 5.7 million people in the U.S. were suffering from Alzheimer's disease in 2018. Moreover, increasing adoption of gene therapy is also expected to aid in growth of the market. For instance, in March 2020, AVROBIO, Inc., a clinical-stage gene therapy company, announced that a second patient in the AVR-RD-04 Phase 1/2 clinical trial in cystinosis has been enrolled and has completed apheresis. Read more @ https://coherentmarketinsights-blog.blogspot.com/2020/12/high-prevalence-of-alzheimers-disease.html

Avocado oil is an edible oil extracted from the pulp of avocados, the fruit of Persea Americana. It is a heart-healthy oil, high in oleic acid, which is an unsaturated fat. It is a good source of monounsaturated fat that has been linked to increasing HDL cholesterol and reducing LDL cholesterol. Moreover, avocado oil help control of psoriasis and osteoarthritis, and some of the benefits associated with avocado oil make it useful for the treatment of carotid artery disease, peripheral artery disease, and coronary heart disease, among others. Furthermore, due to its moisturizing and regenerative properties, avocado oil is widely used in the cosmetic industry. The beta carotene, fatty acids, lecithin, protein, and vitamins E, D, and A found in avocado oil help protect and moisturize the skin from damaging UV rays and also increase collagen metabolism. Read more @ https://sachinbhombe.blogspot.com/2021/08/avocado-oil-better-suited-for-high-heat.html

Blocked blood vessels can complicate medical conditions that may result in fatality. As a result, artificial blood vessels are used to replace these damaged blood vessels. Artificial blood vessels refer to tubes made from various synthetic materials in order to restore and normalize blood circulation during disease conditions. They are mainly used to substitute aorta and are connected to two ends of blood vessels. These artificial blood vessels comprises biosynthetic materials like Polydioxanone and polyethylene terephthalate, due to mechanical properties such as high resistance against water and chemical, high oxygen permeability and high conductivity.

Wheeled platforms with specially-molded seating systems interfaced with them for users with a more complicated posture. A molded seating system involves taking a cast of a person's best achievable seated position and the either carving the shape from memory foam or forming a plastic mesh around it. This seat is then covered, framed, and attached to a wheelbase this becomes more of a custom wheelchair then a standard type. Heavy Duty/High Weight Capacity is a collection of mobility products with expanded maximum weight capacities. Heavy duty wheelchairs, bariatric scooters and more, combined with an expert staff. Heavy duty/high weight capacity wheelchairs feature additional crossbraces for support and heavy duty/high weight capacity electric mobility products have stronger motors to accommodate a higher weight. Heavy Duty manual wheelchairs have a reinforced heavy-duty frame that accommodates weight capacities ranging anywhere from maximum weight depending on the chair. Heavy Duty Wheelchair is strongly constructed and offers a high degree of comfort to larger users. As expect from a wheelchair of this quality, the detachable footrests swing away, the armrests flip back, and the backrest can be folded. The frame is as compact as possible whilst still allowing a wide, comfortable seat (available in 20 or 22" seat sizes), and the extra-wide castors are designed to meet the demands of heavy use. Heavy Duty is a quality option for anyone for a self-propelbariatric wheelchair. Karma 8520 Heavy Duty Wheelchair: It comes with detachable swing away footrests. The wheel chair has flip-back armrests. It comes with centre of gravity adjustment. The wheel chair has wide profile casters. Seat Size 20'' inch & 22'' inch Total Weight 17 K.G. Features : Foldable, lightweight frame for easy portability. Steel double cross-brace frame. Adjustable-tension back upholstery. Armrests are padded, adjustable and removable. Adjustable-length controller mount. Adju

A reclining wheelchair allows several key parts of the device, including the foot rests and backrest, to be adjusted to accommodate various needs and positions. Reclining wheelchairs are high back wheelchairs that allow the user to recline from a 90 degree position down to 180 degree position. Reclining wheelchairs have handbrake-like controls that release the back and lock it into place. Reclining wheelchairs are equipped with removable full support headrests, swing away elevating leg rests and padded arm rests for additional support and comfort. Like standard wheelchairs, reclining wheelchairs fold compactly for easy transport and storage. Different Types Of Reclining Wheelchairs: Reclining Wheelchair 902 GC Reclining Wheelchair 609 GC Karma Aurora 4 Reclining Wheelchair Karma Reclining Wheelchair KM 5000 Karma VIP 515 Wheelchair Reclining backrests can be a useful feature for children: Are unable to sit upright for sustained periods because of weak muscles in the upper body, or a stiff spine or hip. Have difficulty breathing. Are receiving treatment that require them to be in a reclined position. Karma Aurora 4 Reclining Wheelchair: Frame Style : Fordable Frame Material : Aluminium (Light weight) Seat Width (inches) : 18" Total width in wheel to wheel : 11" Rear Wheel Size : 24" Front Wheel Size : 7" Seat to floor height (inches) : 20" Seat Depth (inches) : 16" Back height (inches) : 35" Total height (inches) : 50" Max User Weight Capacity (kgs) : 120 Net Weight (kgs) : 13.5 k.g. Upholstery : Cloth water-proof. Armrest : Detachable, for easy transfer to bed. Leg-rest : Detachable, can also be elevated & with calf support for added comfort Wheel Quality : MAG WHEEL Rear Wheel Brakes : Available Hand brakes : Available Reclining Wheelchair Features: Lightweight aluminum wheelchair. Double crossbraces for extra strength. Folding frame. Padded detachable armrests with side panels. Length-adjustable leg supports. Punctu

Tynor Exercising Ball Exercising ball is an excellent physiotherapy device to provide a pleasurable exercise plan for the hand, wrist, forearm and the fingers Safe and inert. High patient compliance. Excellent resilience for a long functional life . Compatible in thermal/hydrotherapy. Tynor Exercising Ball Features Ergonomic design and materials Two resistances available- Ortho (hard) & Neuro (soft) Compatible for thermal/hydrotherapy Flexible and pleasurable exercise schedules can be planned Better compliance Inert PU material, safe to use Excellent resilience, offers longer life. Tynor Exercising Ball Measurements Sizes Available: OR / NR

Dementia is one of the most common age-related medical conditions. As we age, mental processes and memory become affected by changes in the brain, resulting in problems with memory, attention, mood, and behavior. Dementia can occur in anyone, although it is more common in elderly adults and people suffering from other mental disorders such as depression, bipolar disorder, schizophrenia, obsessive-compulsive disorder, and post-traumatic stress disorder. High prevalence of dementia is expected to propel growth of the dementia drugs market. For instance, according to Alzheimer's Association, around 5.8 million people in the U.S. aged 65 and older are living with Alzheimer's dementia in 2020. Moreover, increasing geriatric population is also expected to aid in growth of the market. For instance, according to the U.S. Census Bureau, the U.S. geriatric population is expected to reach 77 million by 2034. Read more @ https://sachinbhombe.blogspot.com/2021/03/high-prevalence-of-dementia-and-r-of.html

A Basic Understanding of Shipyard Workplace Safety Shipyard Workplace Safety is a high importance, high criticality area for safety regulation. This is so because shipyards are among the most hazardous of places to work in. it is estimated that at any point of time, the number and incidences of injuries and fatalities in the shipyard industry is at least twice that of the next most hazardous industry, construction. This calls for urgent and important Shipyard Workplace Safety regulations. Present Shipyard Workplace Safety Regulations OSHA has a number of Shipyard Workplace Safety regulations for this industry. These need to be read with CFR Title 29 Code of Federal Regulations (CFR) Part 1915, which not only lay out regulations, but also prescribe codes and methods of implementation of these regulations. Why these two regulations need to be implemented together is that there may be a few hazards not covered by Shipyard Industry standards set out by OSHA. These gaps are covered by the regulations set out in CFR 1915, making these a well-rounded set of regulations for Shipyard Workplace Safety. The need for Shipyard Workplace Safety regulations The need for Shipyard Workplace Safety is acutely felt because of the sheer variety of hazards that present themselves in shipyards. Shipyards, which employ between a few dozen and a few thousand employees each, are a site of potentially serious accidents. Even if accidents do not occur, the very nature of work done at these shipyards can be dangerous and hazardous. Shipyard Workplace Safety is a core requirement that employers in this industry have to keep in mind and put in place. The nature of their work could range from and include any or many of these: Scrapping Demolition Electrical Fabrication Creating large and heavy steel or iron plates, sheets, beams, pipes and related items Soldering Drilling Dealing with propulsion systems Welding Shipyard Workplace Safety has to begin with an understanding of these issue

Overview: As the healthcare industry moves toward a value based reimbursement model rather than fee for service, it is crucial that the provider and ancillary staff understand how ineffective reporting can lead to dollars lost. We will review the 3 critical areas that require skilled management. Understand that patients are more educated about their healthcare and are increasingly responsible for more out of pocket costs. High dollar deductibles may result in self pay realities and bad debt increases. Learn areas that increase your chances for an audit. Are you ready for the challenge? Why should you Attend: Revenue is dependent upon proficiency in multiple areas. In today's environment, it is risky to maintain the status quo and increasingly important to obtain and maintain skilled business staff. The granularity of the ICD-10 code set requires understanding of the official coding conventions and guidelines, the ability to apply those guidelines, and the ability to recognize when reporting may lead to revenue delay, reduction or loss. Additionally, other factors affect your revenue stream. This includes patients with high deductible plans, collection of much more than a small co-pay, and staff understanding of regulations that govern telephone collection activity. Don't leave money on the table or invite an audit into your practice. Audits are often the result of weak billing and coding skills. This program will review several areas that will cost you money if poorly handled. Areas Covered in the Session: Required specificity in coding Documentation necessary for ICD-10 reporting Why coders must frequently query for clarification How ambiguous diagnosis reporting affects you r bottom line Internal collections versus outsourcing. What should you consider Staff effective in handling problem claims? Developing appeals? Who Will Benefit: Coders Billers Revenue cycle Physicians Mid-level providers Nurses Claims follow-up Managers Managers Speaker Profil

Overview: Many medical entities are increasingly struggling to manage revenue effectively. Self pay is on the rise due to high deductibles. Bad debt is increasing. What is your plan to manage these areas? Staff trained in denial management? Variances? Are they handling these areas in a timely manner? Payers have time limits in which dollars can be salvaged. Missing those strategic times mean dollars lost. Don't leave money on the table. We will discuss multiple avenues in which strong training and timely action can equal $$$. Why should you Attend: Don't lose hard earned revenue. Learn tips to strategic follow up, when and how to manage the appeal process. Is the claim appealable? Partial payments and why? Today's industry of high dollar deductibles create the necessity to expend additional efforts on self-pay accounts. There is a significant difference in collecting small co-pays and managing large balances. Bad debt creep? What is your plan for managing these areas? Areas Covered in the Session: Hire the right staff - Then engage in ongoing education Variances and denial management Billing compliance Coding for specificity, co-existing conditions and correct modifiers Supporting medical necessity CCI edits and unbundling Productivity Claims follow up Payer processing edits Additional development requests Handling problem claims and appeals Who Will Benefit: Coders Billers Revenue cycle Physicians, mid-level providers Nurses Claims follow-up Managers Speaker Profile Dorothy D. Steed is an Independent Healthcare Consultant and Educator in Atlanta. She was a Medicare specialist for a large hospital system and a physician coding audit supervisor for another hospital system, with 38 years of experience in healthcare. Additionally, she is an instructor at a state technical college in Atlanta, provides auditing & training in both facility and physician services, and has been a speaker at several healthcare conferences. Ms. Steed has written articles for

Tynor Elastic Wrist Splint Tynor Elastic Wrist Splint is designed to immobilize and provide firm support to hand and wrist in various orthopedic conditions. It maintains the wrist in the dorsi flexion functional position while allowing full range of motion to fingers and thumb. The splint can be removed to permit, therapy sessions, washing and hygiene. Malleable Splint. Perfect Immobilization Controlled compression. Anatomical thumb opening. Tynor Elastic Wrist Splint Features High quality Elastic Webbing Strong and durable Porous and comfortable High modulus of elasticity-- Retains shape and size for a long time. Removable, Aluminum Splints Customized fitting Required degree of dorsi-flexion can be achieved Very good grip and immobilization Hook loop closures Easy to apply and remove Ensures optimal compression. Built in opening for thumb abduction Better pain relief and healing. Thumb remains relaxed, no fatigue mproves comfort Tynor Elastic Wrist Splint Measurements Measure circumference evenly around the wrist

Electric wheelchair is a chair fitted with wheels. The device comes in variations allowing either manual propulsion by the seated occupant turning the rear wheels by hand, or electric propulsion by motors. There are often handles behind the seat to allow for different individuals to push. Electric Wheelchairs are used by people for whom walking is difficult or impossible due to illness, injury, or disability. Disabled People who have difficulty sitting and walking often make use of a wheelbench. A basic manual wheelchair incorporates a seat, foot rests and four wheels: two, caster wheels at the front and two large wheels at the back. The two larger wheels in the back usually have handrims; two metal or plastic circles. Electric wheelchairs are propelled by a motor and battery. They are very sophisticated. They are operated with a joy stick or push buttons. Some electric wheelchairs use advanced technology and can climb up stairs, move across gravel and even raise up to give access to high shelves. Electric wheelchairs need strong frames to support the motor and battery so they are very heavy and also quite expensive. People with spinal cord injuries face similar decisions. Often a person with a spinal cord injury will use a motorized wheelchair, even though they are physically capable of using a manual chair. They don't do this because they are lazy. They do this to be more efficient with their energy reserves. People with spinal cord injuries often choose motorized wheelchairs to preserve their physical energy, so that they can complete the work. Sometimes need to save on physical energy so that have some allowance left over for intellectual or emotional pursuits. Karma KP 10.2 Power Wheelchair: Features: Seat, base & battery quickly detach for easy storage and transportation Come with captain seat With seat platform, the captain seat can be moved forward or backward using tools which is included Adjustable armrest width and height Footrests can b

Ergonomic Wheelchair often spend a lot of time leaning on armrests or a table exactly because they are not being supported with good posture in their chairs. This is a matter of seat angle and back angle, adjusting them according to body shape and degree of upper body balance. Poor seating makes slump, trying to get stable. The optimal posture is more upright, allowing spine to support. Ergonomic chairs are designed to confirm to a person's physical dimensions, allowing them to sit naturally and comfortably for long periods of time, while reducing the risk of pressure ulcers. Ergonomic system (Intelligent s-shaped ergonomic seating) provides efficient pressure relief by spreading weight over a greater area, at the same time provides stabilization and reduced sliding. With their lightweight frames and seats designed to reduce or prevent pressure points, ergonomic wheelchairs provide a comfortable option for mobility impaired users who have the upper body strength to propel themselves, or a caregiver strong enough to do so. Karma S Ergo 115 Wheelchair: This model features our S-Shape Seating System and is our number one best seller for many reasons. At a mere 11.3 kg in weight with detachable foot rest and many features such as removable machine washable and dry-able cushions treated by AEIGIS treated anti-microbial coated seating system. Karma S-Ergo 115 Wheelchair Features: Ergonomic Handrims & S-Shape Ergonomic Seating System Fixed armrest w/ wider concave armpads Swing In & Away Footrests Backrest Pouch attached to the upholstery 24" flat free polyurethane tires, high tread, flat free wheels Seat width: 16"x17" or 18"x17" or 20"x 17" Silver 1/4" Aegis Anti-Bacterial Upholstery, washable Folding backrest / folding seat for easy traveling "Tube-in Center" foot-plate, assures better side leg support High strength, starting weight at only 11.3 kg. (w/o footrests) 7×1" Polyurethane front casters Upholstery: Black breathable mesh bottom & t

Pediatric wheelchairs enable child or teen to participate in all types of daily activities. Pediatric wheelchairs are lightweight, portable, and convenient for use at school, day programs, doctor visits, and recreation with family and friends. Pediatric wheelchairs comes in wide range of sizes and vibrant colors for every lightweight wheelchair. A variety of positioning options are also available. Pediatric wheelchairs are manufactured with unsurpassed quality and style, specializing in compact-folding, lightweight wheelchairs for children of all ages - from toddlers to teens! Custom built to child's specific needs, mobility aids offer rehabilitative benefits for physical disabilities from Cerebral Palsy to Autism. Pediatric, or child wheelchairs, are mobile aids designed for and used by children. Children require the use of a wheelchair for many different reasons, some may have suffered head injuries, some have muscular dystrophy or cerebral palsy, some are amputees, and others only have an occasional use of their wheelchairs in lieu of a walking device or crutches. Certain types of pediatric wheelchairs are built to expand in size to accommodate increased bulk and weight by altering a cross balance on the bottom of the chair. The front frames for the legs can be lengthened as child's legs grow longer. For a pediatrician seeking to prescribe a Pediatric Wheelchair, must be sure that the patient has the proper upper body strength to use one. If the patient is too weak for self movement, the practitioner would be better to consider a powered wheelchair for mobility. While Pediatric Wheelchairs are smaller and can be just as manuverable as scooters, that depends upon the patient's own abilities in steering the chair. These are factors that the doctor must think about before recommending what type of wheelchair a patient should get. Pediatric Wheelchair with a body contouring S-Shaped seat frame and contoured armrests provides the user with all day comfort an

Lightweight Ergonomic Wheelchair is designed to cradle patients in comfort while reducing risk of pressure sores, relieving pressure, dispersing weight evenly and improving stability. The Ergo Lite Wheelchair is easy to lift and its small size makes it ideal for travel. Weighing only 19.8 lbs., the chair is easy to store and transport. The chair folds down the middle like a standard wheelchair and the backrest also folds down to make the wheelchair even more compact. Also features companion brakes located on handles for added safety and comfort. Ergonomic Wheelchairs are ultra lightweight and have a supportive seating system to provide pressure relief and anti-slippage giving the user excellent stability and posture support. . Better Ergonomic wheelchair for Comfort: Sit for any length of time in a fixed position in a traditional transport chair and it will feel how painful bad ergonomics can be. It is fully reclined 25° angle, which minimizes slumping and sliding. And because of this can be easily adjusted with the push of a button, it can change positions frequently over time, reducing the chance of secondary conditions that may include pressure sores. Designed to Fit Almost Everyone: It is one of the most extensively researched seat profiles specifically design to accommodate users ranging in size from small women to large men, with the greatest amount of comfort and proper posture/spinal support. The Karman wheelchairs are exceptional in both their function and style. With comfort built right into the frame of a wheelchair eliminating the need for a "thick cushion" to add comfort, S-Shape seat allows the wheelchair to be "ergonomically correct" putting into a seating position and comfort conforming to natural body's curves. These chairs are built for comfort and quality to stand the test of time. Ergonomic Wheelchair is Right: Ergonomic Wheelchair is designed for users who will spend a large amount of time in the chair. This wheelchair'

Overview: Safe hospital care in neither a science nor an art. It is a practice just like the practice by a doctor who combines hindsight of experience and foresight of imagination to come up with an outsight of the best interventions and best protocols. Over time the doctor standardizes the process but is vigilant to any unique requirements of each patient. Such an approach in patient safety is called hazard analysis and mitigation process. This webinar goes a big step farther. It covers innovation strategies to assure that the safety improvements result in a high return on investment and high value to the hospital, and protects the patients. Why should you Attend: About 400,000 patients die each year from hospital mistakes according to a senate hearing. Evidence based methods to reduce adverse, sentinel, and never events are available and successful in aerospace, nuclear, and chemical industries. Why not use them? We need a paradigm shift. We need it in a hurry! You cannot cross the sea merely by standing and staring at the water. Do not be afraid to take a big step if one is indicated. No noble thing can be done without risks Areas Covered in the Session: The Etiologies of Unsafe Care Sufficient Understanding is a Pre-requisite to Safe Care Preventing "Indifferencity" to Enhance Patient Safety Continuous innovation is better than Continuous Improvement Innovations Should Start with Incidence Reports Hazard Analysis Fault Tree Analysis-the Best Tool for Harm Prevention Doing More with Less is Innovation Re-Invent Quality Management Human Errors may be Unpreventable, Preventing Harm is an Innovation Managing Safety: Lessons from Aerospace Protect Patients from Dangers in Medical Devices The Paradigm Pioneers Aequanimitas,The Best Known Strategy for Safe Care Who Will Benefit: Hospital senior management Hospital administrators Doctors Nursing staff Clinical engineers Radiology staff Infection control staff Patient advocates Speaker Profile Dev Raheja

Cervical Collar Soft Firm Density Cervical Collar Soft (Firm Density) is used for supporting, immobilizing or adjusting the neck in the flexion, extension, or hyperextension position. Recommended where a partial or controlled immobilization of the cervical region is required. Ultimate comfort Effective immobilization Strong support Excellent aesthetics Long life. Cervical Collar Soft Firm Density Features Made of very high density (60 kg./m3) P.U. foam High immobilization, better support , quick relief, no reinforcement, more comfortable, long life. Anatomical design Uniform support to the mandible, Better immobilization, Better comfort Covered with hypoallergenic cotton stockinet Better patient comfort, no allergy or rash even to sensitive skin. Better compliance Perforated collar body Improved ventilation , more patient comfort, better compliance. Fawn colored stockinette Matches skin color, Better aesthetics. Long hook-loop closure tape Ensure snug fitting around neck, easy application and quick removal.

Overview: Health care practitioners and other licensed professionals work in today's diverse, fast-changing, multidisciplinary environment. All licensed professions have higher rates of drug abuse, alcohol abuse, and mental health issues. Yet each individual profession has a unique, though similar, state laws which govern how state licensing agencies take action against the professional so as to protect the public. The state's authority and power over licensed professionals often presents challenges to the impaired practitioner that are not easy to navigate. All licensed professionals must adhere to standards of state law which govern their professional practices and include prohibitions for impaired practice - even impairment along that is apart from any direct professional harm. Complaints that are received and investigated by a state agency leave the licensed professional with an uncertain process to handle the state action against them. Coupled with numerous related consequences, such as loss of employment, family issues and divorce, and criminal actions, the licensed professional must handle all these challenges successfully. Learn to identify and understand varying state laws that apply to allow disciplinary action against the licensed professional, both immediately and temporarily, and those which are permanent and final. Review the most common successful elements of the rehabilitation of the licensed professional faced with the deadly consequences of addiction. Compare and contrast regulatory laws and due process requirements for state action. This allows the licensed professional to avoid career-ending sanctions and to defend successfully against legal actions which may result in ruinous practice and career consequences for the professional. This program offers an objective, thorough review of laws which apply to the impaired licensed professional. Why should you attend: Health care practitioners are faced with a higher lifetime risk of drug abuse,

Tynor PUF Liner Skin Traction Set Skin traction Set (PUF liner) is used for providing indirect traction to leg or the arm to reduce fractures, skeletal deformities, muscle contractures, muscle spasms, pressure on nerves or regain normal length and alignment of involved bone. Hypoallergenic. Extra porous. Controlled adhesion and friction. Extra comfortable. Tynor PUF Liner Skin Traction Set Features Available as Complete Kit Convenient for emergencies Cost effective High performance Inbuilt cord, Quick to apply Foam liner and Bandage High performance crepe bandage for extra security Enhanced skin friction of the foam liner Easy application and removal Measure distance from knee to foot. Cut Liners for accurate use