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March 13, 2009 -- Whether you drive, take the bus, or bicycle, being in heavy traffic triples your risk of heart attack within one hour. Air pollution from car fumes is the likely culprit, suggest Annette Peters, PhD, and colleagues at the Institute of Epidemiology, Helmholtz Center, Munich, Germany. In a previous study, Peters and colleagues found that a sizeable proportion of heart attacks -- about 8% -- could be attributed to being in traffic. To follow up, the researchers interviewed 1,454 people who survived heart attacks. In the hour before their heart attack, many of the survivors had been in heavy traffic. Analysis of the data showed that these heart-attack-vulnerable people were 3.2 times more likely to suffer a heart attack if they'd been in heavy traffic in the previous hour.

New evidence by researchers at the Centre for Addiction and Mental Health (CAMH) and researchers in Germany shows that drinking alcohol is the greatest risk factor for acetaldehyde-related cancer. Heavy drinkers may be at increased risk due to exposure from multiple sources.

Benfotiamine (rINN, or S-benzoylthiamine O-monophoshate) is a synthetic S-acyl derivative of thiamine (vitamine B1). After absorption, benfotiamine can be dephosphorylated by cells bearing an ecto-alkaline phosphatase to the lipid-soluble S-benzoylthiamine. The primary use of this antioxidant is as an "anti-AGE" supplement.[3] In a trial, benfotiamine lowered AGE by 40%.[4] However, in Germany doctors have been known to combine benfotiamine with pyridoxine hydrochloride and use it to treat patients with nerve damage and nerve pain such as sciatica. At high doses, benfotiamine was shown to be effective for the treatment of diabetic retinopathy, neuropathy, and nephropathy. I