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A new study has recommended that ladies should follow a high-protein meal with 0.5 an hour of moderate exercise because it burns a lot of calories as compared to physical exercise on an empty abdomen.

Creative Animodel's scientists are researching over gene editing methods and developed TALENs technology to use for gene editing. TALENs are a process of binding proteins in DNA sequence. It's a very powerful approach for genome editing in most of the animal models.

Bioinformatics is the outcome of technological development in the field of biology. We all are aware that bioinformatics has wide applications. By taking the advantage of bioinformatics, the scientist revealed the information about the intrinsically disordered proteins.

There are many sports and fitness related supplements available in the market but Amino Acids are the compounds that constitute protein. If you are a regular at the gym, you can consider taking Branched Chain Amino Acids or BCAAs.

Chia seeds are tiny black seeds from the plant Salvia hispanica, which is related to the mint. Chia seeds were an important food for the Aztecs and Mayans back in the day. They prized them for their ability to provide sustainable energy. In fact, "chia" is the ancient Mayan word for "strength." Despite their ancient history as a dietary staple, chia seeds became recognized as a modern-day superfood only recently. In the past few years, they have exploded in popularity and are now consumed by health conscious people all over the world. Bringing you the tiny little organic chia seeds that are raw & unroasted and are packed with nutrition and health to be perfectly incorporated into traditional Indian diet with a nutty taste. This superfood is loaded with protein, fiber, calcium and magnesium to make your food more nourishing.

Japanese pharmaceutical firm Eisai Co plans to seek full approval of its experimental Alzheimer's drug lecanemab in the United States, Europe and Japan armed with data showing it can slow the brain-wasting disease for people with early symptoms, potentially getting the treatment to patients next year. It remains unclear how widely the drug developed with U.S. biotech Biogen Inc will be used due to uncertainty over insurance coverage, including the U.S. government's Medicare plan for people age 65 and over, potential side effects and cost. One Wall Street analyst told Reuters news agency that he is not counting on measurable sales until 2024. Several estimated lecanemab may be priced at around $20,000 per year. "Most people who this (drug) would apply to are on Medicare, and most private payers look to Medicare as they make their own (coverage) decisions. So there's a massive roadblock in the way of all who could benefit from this treatment," said Robert Egge, Alzheimer's Association chief public policy officer. Eisai confirmed on Tuesday (November 30) that lecanemab - an antibody designed to remove sticky deposits of a protein called amyloid beta from the brain - reduced the rate of cognitive decline on a clinical dementia scale by 27% compared to a placebo. It also gave new details on side effects including a dangerous type of brain swelling and brain bleeding.

Pharmaceutical giant AstraZeneca will acquire biotechnology company Neogene Therapeutics for up to $320 million, the London-listed drugmaker said on Tuesday (November 29) as it seeks to build its pipeline of cell-based cancer treatments. Though AstraZeneca's oncology portfolio accounted for more than a third of the company's revenue last year, it does not have an approved cell-based cancer therapy and is behind rivals such as Novartis and Gilead. "Neogene's leading (T-cell receptor) discovery capabilities and extensive manufacturing experience complement the cell therapy capability we have built over the last three years," said Susan Galbraith, AstraZeneca's executive vice president of oncology research. Cell-based treatments are a relatively new approach to treating cancer, most of which involve drawing the body's own immune cells and processing them in the lab to target and kill cancer cells. Neogene's approach goes one step further in that its experimental T-cell receptor therapies seek to target DNA mutations specific to tumours, not only certain proteins on the surface of cancer cells.

You've heard the beauty benefits of turmeric from your grannies; you may know how turmeric soap benefits your skin. Many studies advocate curcumin's skin-lightening effects, a polyphenol emanating from turmeric. There's also evidence to back its anti-inflammatory and antimicrobial features. Meanwhile, it's a rich source of antioxidants. The golden powder is not only for flavoring up curries; it is also a mainstay in Ayurvedic therapies, both as a tonic and as a beauty agent. The purported skin benefits of this natural turmeric soap include: Skin Whitening Benefits Skin Conditions Fades dark spots Treats acne Fight Aging Meeting any beauty assertions with a healthy dose of suspicion is wise. (After all, if you've ever undergone distressing skincare bents such as peel-off masks, you might think twice before going for other trends.) Fortunately, turmeric soap emerges to deliver benefits to the skin. Turmeric Soap Benefits Although not tangible, analyses indicate that turmeric will soon become a low-cost substitute for relieving skin diseases like eczema, alopecia, etc. Soaping with a turmeric soap bar can help you enhance your skin health in numerous ways. And what's more? Here are excellent turmeric soap benefits that will improve your overall skin health. Turmeric Soap Benefits Blood Circulation that results in Skin Whitening. If your major skin issue is dullness, try to check out turmeric since it's a natural exfoliator. Numerous animal and test-tube studies have shown that turmeric and curcumin extract can boost glutathione levels. Researchers conclude that the curcumin found in turmeric can assist in restoring adequate levels of glutathione and improve the activity of glutathione enzymes. It has the power to slough off your dead skin cells, remove pollutants, and clear oil or makeup build-up, leaving you with a smooth and healthy glow. Regular use of turmeric soap benefits your skin's glow and brightens it naturally. This is why turmeric is also

Diabetes drugs that also promote weight loss such as Novo Nordisk's Ozempic, becoming a darling of celebrities and investors, are being studied to tackle some of the most difficult-to-treat brain disorders, including Alzheimer's disease. Diabetes regimens, from Ozempic to old mainstays like insulin and metformin, appear to address several different aspects of the metabolic system implicated in Alzheimer's disease, including a protein called amyloid and inflammation, researchers say. The hope is that improving glucose utilisation and tamping down inflammation in the entire body - including the brain - could slow progression of debilitating diseases like Alzheimer's and Parkinson's. Several scientists interviewed by Reuters news agency pointed to mounting research supporting testing diabetes drugs against neurodegenerative diseases. Results are years away and success uncertain. But interest has been buoyed by recent positive data on Alzheimer's drugs developed by Eisai with partner Biogen and by Eli Lilly demonstrating that removing sticky amyloid plaques accumulated in the brain can slow cognition decline caused by the fatal mind-wasting disease. Those successes followed decades of futility that had left many questioning the validity of the amyloid theory behind most experimental Alzheimer's drugs.

AstraZeneca said on Monday (June 27) two of its existing therapies were recommended for treating patients with some forms of high-risk breast cancers in the European Union, in a boost to the company's oncology portfolio. Lynparza, a cancer drug developed jointly with U.S.-based Merck, was backed for standalone use or in combination with endocrine therapy in adults with a form of genetically mutated early-stage breast cancer. The drug, which has received a similar recommendation in the United States in March, is a key asset for AstraZeneca. It was recommended in patients with low-to-normal levels of a protein known as HER2 that is the target of several new therapies. Enhertu - developed jointly with Japan's Daiichi Sankyo (4568.T) - was the other drug that was endorsed by the European Medicines Agency for treating an aggressive form of breast cancer characterised by a high rate of HER2.

The National Institute for Health and Care Excellence (NICE) has recommended pembrolizumab in combination with chemotherapy (paclitaxel or nab-paclitaxel) which is said to benefit people with triple negative breast cancer. Clinical trial evidence shows that, compared with paclitaxel, pembrolizumab combination increases how long people have before their cancer gets worse and how long they live. NICE already recommends atezolizumab in combination with chemotherapy for untreated PD-L1-positive, locally advanced or metastatic, triple-negative breast cancer. Atezolizumab combination is recommended by NICE for people with IC equal to or greater than 1%. "This means that some people who can't have atezolizumab combination could be eligible for pembrolizumab combination," said NICE. NICE's independent appraisal committee also agreed that the pembrolizumab combination meets the higher cost-effectiveness threshold for life-extending treatments for people with a short life expectancy. Given by injection every 3 weeks, pembrolizumab (also called Keytruda and made by Merck Sharp and Dohme) is a type of immunotherapy that specifically targets triple negative breast cancer. It works by blocking the activity of a protein known as PD-L1 which is produced in larger amounts on cancerous cells than normal cells. By blocking PD-L1 it helps the person's own immune cells to attack the cancer.

Japanese drugmaker Eisai said on Tuesday (January 10) it had submitted a marketing application to the European health regulator for review of its Alzheimer's drug lecanemab, which was recently granted accelerated approval in the United States. The drug, developed in partnership with Biogen, is an antibody that has been shown to remove sticky deposits of a protein called amyloid beta from the brains of those in the early stages of the mind-wasting disease. Nearly all previous experimental drugs using the same approach have failed. The company's application to the European Medicines Agency is based on results from a late-stage study in which the drug was shown to slow down the rate of cognitive decline in patients with early Alzheimer's by 27 per cent, compared with a placebo. Eisai also reiterated its plans to apply for marketing authorization of the drug in Japan by the end of its business year on March 31.

One of the long-standing medical mysteries is the diagnosis of diabetes in majority of patients suffering from high blood pressure. The reason for this had been unknown. But now, an international team of universities have made a breakthrough. The research, published online in 'Circulation Research', involved contributions from collaborating scientists in Brazil, Germany, Lithuania, and Serbia, as well as the UK and New Zealand. The important new discovery has shown that a small protein cell glucagon-like peptide-1 (GLP-1) couples the body's control of blood sugar and blood pressure. Professor Julian Paton, a senior author, and director of Manaaki Manawa, The Centre for Heart Research at the University of Auckland, said: "We've known for a long time that hypertension and diabetes are inextricably linked and have finally discovered the reason, which will now inform new treatment strategies." GLP-1 is released from the wall of the gut after eating and acts to stimulate insulin from the pancreas to control blood sugar levels. This was known but what has now been unearthed is that GLP-1 also stimulates a small sensory organ called the carotid body located in the neck.

Esperion Therapeutics' non-statin therapy "bempedoic acid" has shown modest results in reducing the risk of major cardiovascular events in statin-intolerant patients in the cholesterol lowering via bempedoic acid, an ACL-inhibiting regimen (CLEAR Outcomes) trial, revealed GlobalData, a leading data and analytics company. As a result, there is substantial room for improvement in this space as a potential approval is expected in Australia in near-term based on these results, said GlobalData. According to GlobalData's Pharmaceutical Intelligence Center, the total number of diagnosed prevalent cases of dyslipidemia in Australia is expected to increase at a compound annual growth rate of approximately 1.2% from 5.2 million in 2022 to 5.4 million in 2025. Neha Myneni, Pharma Analyst at GlobalData, comments: "Bempedoic acid joins several statin alternatives that have shown the potential to reduce cardiac illnesses. However, with not much significant improvement in the outcomes, there exists a clear room for improvement for non-statin therapies in this space." Bempedoic acid is the sixth class of cholesterol-lowering drugs (other than cholesteryl-ester transfer protein isoform (CETPi) inhibitors), that has demonstrated the potential to reduce heart attacks and strokes. Other class of therapies with similar potential currently marketed in Australia include statins, bile acid resins, niacin, ezetimibe, and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors (alirocumab, evolocumab, and inclisiran).

The European Union's health regulator on Friday said it had recommended granting a conditional marketing authorisation for a gene therapy by Australian drugmaker CSL Ltd and partner uniQure N.V. , to treat haemophilia B, a rare bleeding disorder which is caused by genetic anomalies. About one in 40,000 people are affected by the inherited disorder, caused by a gene mutation that hampers the body's ability to make clotting protein factor IX. If approved, the treatment, branded Hemgenix, will be the first gene therapy in the European Union for the condition that is usually treated by regular injections of factor IX, the European Medicines Agency said. CSL had acquired exclusive global rights to Hemgenix in May last year from uniQure N.V.

The subject of today's article is the benefits and uses of Tripeptide-29. Let's dive right into it! The three-amino-acid peptide known as Tripeptide-29 consists of glycine, proline, and hydroxyproline amino acids. Collagen peptide is another frequent name for this peptide since it occurs naturally in animal collagen. Animal studies have indicated that topical Tripeptide 29 may minimize the look of fine lines and wrinkles, enhance the skin's texture, and replenish moisture in dry areas. Experts are now studying the effects of Tripeptide on the skin. Place your order now if you need collagen peptide for a study. Continue reading for more information on this peptide. What is the function of Tripeptide 29? One of collagen's primary structural components, Tripeptide-29, is a synthetic peptide. Collagen is the most common protein in the animal body and is essential in developing and maintaining healthy hair, skin, nails, tendons, ligaments, and bones. Glycine, proline, and hydroxyproline are the building blocks of this long-chain polymer. The Gly-Pro-Hyp peptide Tripeptide-29 is a vital part of type 1 collagen.

Covid-19 vaccine maker Novavax on Wednesday said it expects revenue this year to be flat or lower as it works to improve its commercial performance and pick up market share from much larger rivals, Pfizer and Moderna. The company posted a larger-than-expected fourth-quarter loss as revenue lagged analysts' estimates. Chief executive John Jacobs said Novavax claimed just a low-single-digit percentage market share in the US during the most recent vaccination campaign, as demand for Covid vaccines was smaller than hoped and the company got its protein-based shot to market later than its messenger RNA-based rivals. "We were disappointed with that US performance," Jacobs said in an interview. He said the company's sales force was not targeted enough toward retail pharmacy chains, and that its 5-dose vials were not as convenient for use as rivals' pre-filled syringes.

A new study has revealed that UK adolescents get around two-thirds of their daily calories from ultra-processed foods (UPFs), which have been linked to the rising levels of obesity, type 2 diabetes and cancer. The research, funded by the National Institute for Health and Care Research (NIHR)'s School for Public Health Research, was published in the European Journal of Nutrition. Ultra-processed foods are often characterized by poor dietary quality due to their high content of added sugars, saturated fats, and salt, along with lower levels of fibre, protein, and micronutrients. The study, conducted by researchers from the Universities of Cambridge and Bristol, analysed data from four-day food diaries of almost 3,000 adolescents, sourced from the UK National Diet and Nutrition Survey. After examining trends in the UK between 2008/9 and 2018/19, the researchers found that UPFs accounted for 66 per cent of adolescents' energy intake on average during this period.