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The Royal Pharmaceutical Society (RPS) on Wednesday announced that it is spearheading a new project, which aims to delve into the root causes of the growing challenge of medicines shortages across the United Kingdom and provide solutions to mitigate its impact on patients and pharmacy practice. A newly formed advisory group, chaired by RPS Fellow Dr. Bruce Warner, is set to convene later this month. The group will have experts from primary and secondary care, patient advocacy groups, the pharmaceutical industry, suppliers, regulatory bodies, governmental representatives, and NHS officials. The group aims to formulate a robust report to provide expert thought leadership and support for the wider debate on UK policy. Their work will be informed by a thorough literature review, stakeholder interviews, online RPS member events, and patient stories.

What are the main causes (mouth sore) of mouth sore Thrush infection? What is chance? Candida infection is a fungal (yeast) infection that affects many parts of the body. Click Listen audio link Continue to listen Audio this post of this disease Pain? what are the side effects? Treatment!

Click Listen audio link Continue to listen Audio this post of this disease Pain? what are the side effects? Treatment!

Reacting to recommendations from a UK-first independent review, the Department of Health and Social Care (DHSC) has outlined action to tackle potential bias in the design and use of medical devices. Professor Dame Margaret Whitehead, professor of public health at the University of Liverpool, was appointed to lead the review, which focused on three areas - optical devices such as pulse oximeters, AI-enabled devices, and polygenic risk scores (PRS) in genomics. The DHSC commissioned the medical devices review after concerns were raised that pulse oximeters - widely used during the COVID-19 pandemic to monitor blood oxygen levels - were not as accurate for patients with darker skin tones. There were worries that this could cause delays in treatment if dangerously low oxygen levels in such patients were missed. However, no evidence was found from NHS studies indicating that this differing performance had an impact on patient care. Accepting the report's conclusions, the DHSC has committed to several actions, such as ensuring the safe use of pulse oximeter devices across a range of skin tones within the NHS and eliminating racial bias from data sets employed in clinical studies.

The UK based Pharma giant Futura Medical Plc's lead product, Eroxon, a topical Stim-gel is now available on NHS prescription in England and Wales for the treatment of Erectile Dysfunction (ED). The Muti-Drug Resistant (MDR) approved alternative to PDE5i, Eroxon is available as an over-the counter off shelf at retailers like Boots and Superdrug; and is available on NHS prescription in England and Wales as a CE-marked medical device. Erectile dysfunction (ED), also known as impotence, is the inability to get and maintain an erection, typically concerning men over the age of 40 due to both, psychological and physical causes such as anxiety, depression, diabetes, and obesity. According to UK Conformity Assessed (UKCA), the approval of the medication is based on evidence from 2 Phase three clinical studies, which showed that 60 per cent of patients taking Eroxon achieved Minimal Clinically Important Differences (MCID) at 12 weeks.

The Medicines and Healthcare products Regulatory Agency (MHRA) on Monday (29 January 2024) approved the medicine Rezzayo (rezafungin) to treat invasive candidiasis, an infection caused by a yeast called Candida. Invasive candidiasis can pose a serious health risk as it can affect the blood, heart, brain, eyes, bones and other parts of the body. Napp Pharmaceuticals Ltd was granted the marketing authorisation for the medicine based on phase 3 clinical trial data. In the randomised, double-blind, controlled study, more than half of the invasive candidiasis patients who were given a weekly dose of rezafungin were cured at day 14. Among 94 patients who were given a daily dose of caspofungin (another antifungal treatment), 57 of them were cured during the same time.

"Anything is possible with focused strength, resilience and determination" said Bhavin Shah, Financial Director at Sigma Pharmaceuticals plc, after completing the annual London Marathon. Shah donned his running gear and completed the 26.2 mile route in a commendable time of 5 hours and 33 minutes, all in support of 'Team George', a cause initiated by his close friend, Jonathan Bracey, who is the EVP of corporate development at Tanner Pharma Group. Bracey started the crowdfunding initiative last year after his 2-year-old son George was diagnosed with a rare cancer (rhabdomyosarcoma) on his liver/bile duct. Sigma Pharmaceuticals directors and staff have played a vital part in helping raise over £52,000 over the last 6 months for 'Team George', which included the London Marathon Charity run on Sunday 21 April 2024. The funds will be donated to four charities that have been instrumental in George's path to overcoming cancer - Rays of Sunshine ward at Kings College Hospital Charity, St Mary's Hospital, Alice's Arc and Great Ormond Street Hospital. For over three months, Shah had been training himself physically and mentally for the marathon run to support his friend's initiative. He joined Bracey in the marathon, along with more than 50,000 other competitors.

After receiving approval from the National Institute for Health and Care Excellence (NICE), the NHS is preparing to roll out a new combination treatment for brain tumours in children and young people in England. Dabrafenib with trametinib would be the first ever targeted treatment for children (aged 1-17) with gliomas that have a specific genetic mutation, the health service said. The treatment, which can be taken at home, has been found to slow the progression of the disease by over threefold compared to standard chemotherapy in children with low-grade gliomas that have a BRAF V600E mutation. Clinical trials have shown that it causes fewer side-effects than chemotherapy. NICE approved the combination treatment on Wednesday 24 April. It will be available on the NHS in the coming months.

In the next 10 years, the incidence of first-time stroke cases in the UK is projected to increase by 60 per cent, costing the government £75bn in healthcare and lost productivity, a charity has suggested. A new manifesto published by the Stroke Association has urged the next UK government to make stroke "the priority", stressing that the next decade is crucial for stroke prevention, treatment and recovery. Currently, stroke is the UK's fourth biggest killer and a leading cause of disability. On a daily basis, 281 individuals experience a stroke. Next year, the cost of stroke in the UK will be £43 billion. The charity predicted that by 2035, there will be 151,000 hospital admissions due to stroke every year, averaging 414 admissions per day, with 42,000 people estimated to die every year. In 2035, the UK is projected to have 2.1 million stroke survivors, imposing a financial burden of £75 billion on the public purse, nearly half the current NHS budget.

The outbreak of Burkholderia cepacia complex (Bcc) in the UK, which is associated with contaminated eye gels imported from India, has led to the death of one person, and many others falling ill, according to a government report. Bcc is a group of antibiotic-resistant bacteria that are widely found within the environment. Although it rarely causes infection, it can result in severe ones in individuals with compromised immune systems and those living with cystic fibrosis, the UK Health Security Agency (UKHSA) said. Between January 2023 and February 2024, there were 52 confirmed and six probable cases across the UK linked to the bacteria outbreak, as revealed in the Health Protection Report published by UKHSA. Forty-one of these cases were hospital inpatients, 38 of which were in critical-care settings. Twenty-five cases were considered to have "clinically significant infections attributable to Bcc", out of which 11 had eye infections, nine had respiratory infections and four had bacteremia (bacteria entering the bloodstream). Two individuals with cystic fibrosis (CF) were infected, and while one was treated, the other died, with the report indicating Bcc infection to have "contributed to the death."

Adding to the growing evidence of global medicine shortages, a new study has revealed that the European generic medicines market is "not in shape" to help Europe meet its public health priorities. In the past decade, the rate of generic medicines withdrawals has risen by 12 per cent, while there has been a three per cent decrease in the launch of generic products, as per Teva Pharmaceuticals' recent analysis of IQVIA data. Within the mental therapeutic area, seven per cent of generic products disappeared between 2013 and 2023, while there was a seven per cent decrease in the availability of generic cancer medicines in just six years (2017-2022). These medicines were listed on the Union List of Critical Medicines to help avoid potential shortages, as the European Commission (EC) said this could cause "significant harm to patients and pose important challenges to health systems." While mature generic products constitute the majority of the List, they remain susceptible to withdrawals, despite containing products crucial for safeguarding Europe's public health, the Teva analysis report noted. Since 2013, the number of generic products for the treatment of schizophrenia and bipolar disorder has declined by 25 per cent, with Hungary and Bulgaria experiencing the biggest loss at 83 per cent and 58 per cent respectively.

Merseyside Police have appealed for information from the public following the theft of "a large quantity" of medication from a pharmacy in West Derby this week. As per the police report, the burglary occurred in the early hours of Monday, 12 February, at the pharmacy situated on Deysbrook Lane. Authorities were informed at around 9:15 am. Based on the CCTV footage they have recovered, the Merseyside Police revealed that a man entered the pharmacy at around 1.20 am on 12 February and stole a large quantity of medication, including diazepam, codeine, co-codamol, pregabalin, zopiclone. These are prescription-only drugs that could cause "serious harm" if a significant amount is taken, the report said. The suspect, described as a white man of slim build, was wearing a grey coloured tracksuit and glasses, according to the police.

"Record long NHS waits are forcing huge numbers of people out of work, including doctors and nurses," said Wes Streeting MP, Labour's Shadow Health and Social Care Secretary as Labour announced a new partnership with Nuffield Health today to tackle joint pain issues among NHS staff and reducing waiting lists. Musculoskeletal problems, including back, knee, hip, and neck pain, are the second leading cause of NHS staff absences, surpassed only by mental health issues. In December 2023 alone, NHS workers missed a record 198,000 days due to these issues, marking a 13 per cent increase from the 174,000 days recorded in December 2019. Nurses and health visitors accounted for 52,000 of these days, up from 47,000 pre-pandemic, while doctors took 3,500 days off, a 9 per cent increase from 2019. The partnership with Nuffield Health will provide up to 4,000 extra places for NHS staff in Nuffield Health's Joint Pain Programme at no cost.

In a collaborative effort, the National Health Services England (NHSE) is set to deliver the RSV(respiratory syncytial virus) vaccination programme where pharmacists alongside other healthcare professionals will play a crucial role in administering the vaccine. The UK Health Security Agency has announced the launch of the new vaccination programme targeting the respiratory syncytial virus (RSV), set to begin on 1 September 2024. Along with GPs, NHS England (NHSE) will "commission a number of community pharmacies to deliver the programme", ensuring broad accessibility and coverage to protect two high-risk groups: older adults and pregnant women. RSV is an RNA virus related to mumps, measles, and human parainfluenza viruses. It commonly causes coughs and colds in winter, transmitted through droplets and secretions from close contact with infected individuals. While most RSV infections are mild, infants under six months and the elderly are particularly susceptible to severe diseases like bronchiolitis and pneumonia, which can lead to hospitalisation.

The Professional Records Standards Body (PRSB), which develops information standards for health and social care records, has appointed Professor Reecha Sofat as the new Chair. She will assume the role at the end of October 2024, succeeding Professor Maureen Baker CBE, who will step down after seven years as Chair of the PRSB. A Clinical Pharmacologist, Professor Sofat has held many leadership roles across the NHS, academia and scientific societies. Professor Sofat is Breckenridge Chair of Clinical Pharmacology at the University of Liverpool. She practices general internal medicine and is also an Associate Director at the British Heart Foundation (BHF) Data Science Centre (DSC) which is led by Health Data Research UK (HDRUK). With a passion for data science and extensive clinical and research insights, Professor Sofat is focused on embedding research into routine health and social care. She said: "I am passionate about using the rich health data that is already collected across NHS and social care to better understand the causes and consequences of disease and improve health outcomes.

On June 3, Synnovis, a pathology laboratory serving several NHS organisations in South East London, was targeted by a ransomware attack. This cyber incident has disrupted vital blood testing services, crucial for a range of medical treatments, and raised significant concerns over data security. NHS England confirmed that a cybercriminal group, Qilin, published data online, claiming it was stolen from Synnovis. The National Crime Agency (NCA) and the National Cyber Security Centre (NCSC) are currently working to authenticate the data and understand its contents. A helpline has been established to address patient concerns, and NHS England urges patients to attend their appointments unless otherwise directed. The attack has rendered some of the NHS's blood testing systems inoperable, causing substantial disruption to medical services in South East London.

Long appointment wait times, embarrassment, and lack of trust are causing thousands of Brits to avoid visiting doctors, according to new research by Newfoundland Diagnostics. With 1 in 4 individuals resorting to A&E due to the lack of available GP appointments, which adds to the NHS burden, the medical self-testing brand believes that educating the nation on at-home testing can help ease the strain on the health service. The research revealed the top five reasons why Brits avoid visiting doctors for medical testing: Appointments taking too long to book (28 per cent) Embarrassment around their illnesses (15 per cent) Preference for at-home testing (12 per cent) Not having time (10 per cent) Lack of trust in the NHS or their GP (7 per cent) The research team cautioned that delaying care can worsen conditions, resulting in more severe cases that place greater strain on the NHS.

People are advised to be mindful of medications that may cause sun reactions, and to watch out for dodgy hay fever treatments and fake weight loss pens. For those traveling abroad, the MHRA advises considering the suitability of medicines available to reduce the risk of contracting tropical diseases. Dr Alison Cave, Chief Safety Officer at the MHRA, said: "The summer is an exciting time for many of us, as we take time off to travel and enjoy the warmer weather. "But it is important to understand what this time of year means for our medicines and medical devices, and take the precautions necessary to use products safely and protect ourselves." Watch out for dodgy hay fever treatments Millions of Britons suffer from hay fever symptoms in the summer. The MHRA advises consulting a healthcare professional to find the best treatment for your symptoms. People are also warned to be cautious of medicines advertised as hay fever treatments but not approved for use in the UK, such as Kenalog. This is a prescription-only steroid injection licensed as a medicine for other conditions, but not for the treatment of hay fever.

Kent Pharma UK has announced a precautionary recall of multiple batches of Itraconazole 10mg/ml oral solution following the identification of out-of-specification appearance in the solution, particularly the presence of suspended particles or clusters of crystals. Itraconazole is an antifungal medication prescribed for treating fungal or yeast infections in different parts of the body. Its oral solution form is specifically intended for treating oropharyngeal or esophageal candidiasis, commonly known as thrush or oral thrush. The Medicines and Healthcare products Regulatory Agency (MHRA) has advised the recall following initial investigations, which indicated a solubilisation issue of the active ingredient, itraconazole. This problem may result in some doses containing lower amounts of the active ingredient. The root cause of the issue is currently under investigation. However, due to the potential for underdosage, the affected batches are being recalled as a precautionary measure.

Keep your eyes bright and healthy throughout the winter months. Here are some essential tips and strategies to maintain optimal eye health during winter.