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Lyophilization cycles consist of three phases: Freezing, primary drying, and secondary drying. Conditions in the dryer are varied through the cycle to ensure that the resulting product has the desired physical and chemical properties and that the required stability and sterility is achieved and maintained. During the freezing phase, the goal is to freeze the mobile water of the product. Significant super cooling may be encountered, so the product temperature may have to be much lower than the actual freezing point of the solution before freezing occurs. Generating very large frozen particles due to the initial freezing process can cause the sedimentation rate to go way up causing a much longer cycle than effective design of the process can accomplish making the process more cost effective and higher quality. Lyophilization, commonly referred to as freeze drying, is the process of removing water from a product by sublimation and desorption. This process is performed in lyophilization equipment which consists of a drying chamber with temperature controlled shelves, a condenser to trap water removed from the product, a cooling system to supply refrigerant to the shelves and condenser, and a vacuum system to reduce the pressure in the chamber and condenser to facilitate the drying process. Lyophilizers can be supplied in a wide variety of sizes and configurations and can be equipped with options that allow system controls to range from fully manual to completely automated.

This course will describe the latest legal developments regarding new state and local laws. The laws related to leaves are constantly changing and keeping up with state and local laws is particularly challenging. This course will review new state and local laws regarding leaves, including new paid sick leave laws in California and Massachusetts, plus several cities in New Jersey and changes to the paid sick leave laws in Connecticut, the District of Columbia and New York City, new pregnancy discrimination laws in Delaware, the District of Columbia, New Jersey and Illinois, new protections for interns and volunteers in California, a new domestic violence leave law in Massachusetts, the Women's Economic Security Act in Minnesota, and a new law in Philadelphia protecting breastfeeding mothers.

Our #experienced accountants and #financial consultants serve the markets of #UAE with accounting, financial reporting, financial #management, #internal audit and controls, #Value_Added_Tax #(VAT), Excise #Tax, and other taxation #matters.

Our #experienced accountants and #financial consultants serve the markets of #UAE with accounting, financial reporting, financial #management, #internal audit and controls, #Value_Added_Tax #(VAT), Excise #Tax, and other taxation #matters.

Our experienced accountants and financial consultants serve the markets of UAE with accounting, financial reporting

Our #experienced accountants and #financial consultants serve the markets of #UAE with accounting, financial reporting, financial #management, #internal audit and controls, #Value_Added_Tax #(VAT), Excise #Tax, and other taxation #matters.

National News: Tax Tip: Tips for Preparing to File Your Taxes Online OTTAWA, ONTARIO--(Market wired - Feb. 10, 2014) - Did you know? Filing your taxes online is increasing in popularity as Canadians discover how fast, easy, and secure filing online really is. Last year, over 74% of Canadians filed their income tax and benefit return electronically. Are you ready to join them? Get ready: following these steps will make filing your taxes easy! * Go to www.cra.gc.ca/getready to find out about non-refundable credits you might be eligible for to reduce your taxes this year. * Gather all your information slips and receipts (T4s, T5s, etc.), as well as a copy of last year's return to use as a reference for this year. No need to send your receipts in with your return! If we need to see them, we will let you know. * Have your social insurance number and date of birth on hand. * Sign up for direct deposit to receive your refund faster and any benefit or credit payments owed to you, deposited directly into your bank account. Go to www.cra.gc.ca/directdeposit to learn how to sign up for direct deposit. * To file online, you need to complete your return using certified software or a certified web application. This may even help you identify benefits and credits that you may have missed if you filed on paper! The CRA has a list of software options-some that you have to buy and some that you can use for free-at www.netfile.gc.ca/software. Accounting Tips by Hass Associates Individual and Business Tax Preparation

Accounting Tips by Hass Associates Individual and Business Tax Preparation Tax season is officially underway (Jan. 31 - April 15) and while it may be a painful process for some, delaying it can only bring a bigger headache. John Ams, executive vice president for the National Society of Accountants (NSA) says whether you owe money or anticipate a refund, getting it done early can prove beneficial. If you are owed money, your chances of getting it faster are better when you file early. If you owe money, you will at least know how much you owe and can begin saving to pay for it, says Ams. Anyone who hopes to file an extension should remember, it is only an extension of time to file your return, not an extension of time to pay. "You have to file the extension and the money you think you are going to owe. If you substantially underpay, you get a substantial underpayment penalty," Ams says. Taxes are due on April 15, period. And yes, the IRS does charge interest. If your return is not fairly simply, you may want to consult a tax professional for help. You can spend a lot of time spinning your wheels on complex issues, Ams says. If you need tax-preparation help this coming season, you can find a qualified tax preparer in your area, on the NSA website at www.nsacct.org. Click on "Find a Professional" or call 800-966-6679. [Discover More] You can also ask friends or relatives for recommendations, but be sure to find someone with expertise that matches your own financial situation, Ams says. Any tax preparer you use should have a professional tax identification number which he or she uses upon signing your return. You may also qualify for free tax preparation assistance. Click to read

Our experienced accountants and financial consultants serve the markets of UAE with accounting, financial reporting