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Although synthetic polymers are widely used in medicine, in direct contact with blood, these polymers are still prone to initiate the formation of clots due to activation of platelets and other components of the blood coagulation system ([Aiping and Tian 2006]). It is well known that interactions between the surface of an artificial biomaterial and biological environment are the key factor to determine the biocompatibility

In 1987, a group of experts defined the word biomaterial as “a non-viable material used in a medical device, intended to interact with biological systems” (Europeon Society of Biomaterials Conference, 1987). This definition reflected the state of the field at the time, which was focused on developing materials and coatings to prevent the rejection of implantable medical device