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This sort of late-breaking Democratic vote is the new, though still underappreciated, normal in national elections. Americans have become accustomed to knowing who won our elections promptly, but there are many legitimate votes that are not counted immediately every election year. For reasons that are not totally understood by election observers, these votes tend to be heavily Democratic, leading results to tilt toward Democrats as more of them are counted, in what has become known as the "blue shift." In most cases, the blue shift is relatively inconsequential, changing final vote counts but not results. But in others, as in 2018, it can materially change the outcome.

"With each interaction, Alexa is training to hear better, to interpret more precisely, to trigger actions that map to the user's commands more accurately, and to build a more complete model of their preferences, habits and desires. What is required to make this possible? Put simply: each small moment of convenience - be it answering a question, turning on a light, or playing a song - requires a vast planetary network, fueled by the extraction of non-renewable materials, labor, and data. The scale of resources required is many magnitudes greater than the energy and labor it would take a human to operate a household appliance or flick a switch. A full accounting for these costs is almost impossible, but it is increasingly important that we grasp the scale and scope if we are to understand and govern the technical infrastructures that thread through our lives. III The Salar, the world's largest flat surface, is located in southwest Bolivia at an altitude of 3,656 meters above sea level. It is a high plateau, covered by a few meters of salt crust which are exceptionally rich in lithium, containing 50% to 70% of the world's lithium reserves. 4 The Salar, alongside the neighboring Atacama regions in Chile and Argentina, are major sites for lithium extraction. This soft, silvery metal is currently used to power mobile connected devices, as a crucial material used for the production of lithium-Ion batteries. It is known as 'grey gold.' Smartphone batteries, for example, usually have less than eight grams of this material. 5 Each Tesla car needs approximately seven kilograms of lithium for its battery pack. 6 All these batteries have a limited lifespan, and once consumed they are thrown away as waste. Amazon reminds users that they cannot open up and repair their Echo, because this will void the warranty. The Amazon Echo is wall-powered, and also has a mobile battery base. This also has a limited lifespan and then must be thrown away as waste. According to the Ay

Until now, research into regime shifts has focused on critical environmental thresholds, or "tipping points," in external conditions-eg when crossing a certain temperature threshold triggers a sudden shift to desertification. But the new model by Catalina Chaparro-Pedraza and SFI External Professor André de Roos, both at the University of Amsterdam, reveals how a small change in the external environment, with little immediate impact, can induce slow evolutionary changes in the species that inhabit the system. After what the researchers call a "considerable delay," wherein species slowly evolve a new trait or behavior over generations, the regime shift manifests as a delayed reaction.

Great powers rise and fall, shaping each transitional period of global power shift and its geographic concentration. Currently, the world is witnessing a profound transformation in the geopolitical arena of international affairs. For the past years, the pundits have been propagating the emergence of an Asian multipolar century, with a shift from the Atlantic to the Pacific realm. However, following the COVID-19 virus outbreak, this year marks the obvious manifestation of an Indo-Pacific decade, with the US, China, and potentially India being the main protagonists in an emerging competition. This time, it is the unfolding of regional centres of power, which create the delusive impression of multipolarity, while in fact a new systemic bipolarity between the US and China comes to light. In the post-COVID-19 global context, the virus has become a catalyst of multiple systemic changes, inducing ad hoc constellations of regional actors-shaped by their geopolitical and geoeconomic interests-in a changing global order with eroding multilateral structures.

Using two independent single-cell approaches, we identified a shift in the overall immune cell composition in cavefish as the underlying cellular mechanism, indicating strong differences in the immune investment strategy. While surface fish invest evenly into the innate and adaptive immune systems, cavefish shifted immune investment to the adaptive immune system, and here, mainly towards specific T-cell populations that promote homeostasis. Additionally, inflammatory responses and immunopathological phenotypes in visceral adipose tissue are drastically reduced in cavefish. Our data indicate that long-term adaptation to low parasite diversity coincides with a more sensitive immune system in cavefish, which is accompanied by a reduction in the immune cells that play a role in mediating the pro-inflammatory response.

"Right now, the biggest impediment to thinking about the future of the humanities is that, thanks to this entrenched narrative of decline-because we've been crying wolf for so long-we already think we know what's going on. The usual suspects-student debt, postmodern relativism, vanishing jobs-are once again being trotted out. But the data suggest something far more interesting may be at work. The plunge seems not to reflect a sudden decline of interest in the humanities, or any sharp drop in the actual career prospects of humanities majors. Instead, in the wake of the 2008 financial crisis, students seem to have shifted their view of what they should be studying-in a largely misguided effort to enhance their chances on the job market. And something essential is being lost in the process."