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Bone grafting is a medical procedure that replaces missing bone to repair extremely complex bone fractures, usually for major trauma, which poses a risk to the patient if not properly healed, or fail to heal naturally.

Graft-versus-host disease (GvHD) is a systemic disorder and a common complication after allogeneic hematopoietic stem cell transplant. The condition can be subclassified into acute classic GVHD, persistent, recurrent, or late-onset acute GVHD, classic chronic GVHD, and overlap syndrome.

Bone graft and substitutes are terms used for the artificial replacement of bones. These replacements are usually made from artificial titanium. They are used to treat injuries caused by a fracture or other damages to the bones.

The dental bone graft and substitutes market is growing exponentially in recent years. This can be attributed to increasing focus on aesthetic appeal and increasing dental visits.