Glutamate receptors are located in both neurons and glial cells throughout the CNS. The glutamatergic synapse pathways, which are linked to many other neurotransmitter pathways, play a crucial role in a large array of normal physiological functions. The glutamate dysfunction stands out as a key factor in both neurodevelopmental diseases and injury.
Gamma-Aminobutyric acid (γ-Aminobutyric acid, GABA) is the predominating inhibitory neurotransmitter in the mammalian CNS. As exogenous GABA cannot penetrate the blood-brain barrier, it is synthesized in the GABAergic neurons in the CNS, converted from glutamate, the principal excitatory neurotransmitter, using the enzyme glutamic acid decarboxylase (GAD) and pyridoxal phosphate as a cofactor.
MSG allergy symptoms are those symptoms that are due to overeating food that contains monosodium glutamate. Let to learn all about the other ways of dealing with MSG allergy symptoms and the way to prevent them.