PLYMOUTH medical researchers have discovered a link between lack of the 'sunshine vitamin' and the onset of dementia.\n\nTeams from the city's Peninsula Medical School and the universities of Cambridge and Michigan have for the first time found a relationship between lower Vitamin D levels and cognitive impairment in older people.\n\nThe results of their large-scale study are to be published in the Journal of Geriatric Psychology and Neurology.
Heaney RP.
Long-latency deficiency disease: insights from calcium and vitamin D.
Am J Clin Nutr. 2003 Nov;78(5):912-9. Review.
PMID: 14594776 [PubMed - indexed for MEDLINE]
"Dr. Jodie Burton is the acting principal investigator (PI) of the dose-escalation trial of oral vitamin D3 with calcium supplementation in patients with multiple sclerosis with Dr. O'Connor. She started the trial as his fellow, while doing an additional 2 years of training in MS specifically after she received her neurology certification. She completed her fellowship training in 2007. Now she is staff doing clinical research and continuing with the vitamin D trial. As of August 2009, she will be Assistant Professor in Neurology in the Department of Clinical Neuroscience in Calgary and at the University of Calgary. She will be part of the MS team there with Dr. Luanne Metz and the MS group.
Please scroll down for an abstract of the trial:
A Phase I/II dose-escalation trial of oral vitamin D3 with calcium supplementation in patients with multiple sclerosis."
Conclusions:
High-dose VD3 (~10 000 IU/day, possibly higher) in MS is safe and tolerable, with evidence of clinical improvement.
Vitamin D and autoimmune rheumatic diseases.
Cutolo M.
Rheumatology (Oxford). 2009 Mar;48(3):210-2. Epub 2008 Oct 17.
PMID: 18930963
doi:10.1093/rheumatology/ken394
A Lecture by Reinhold Vieth, Professor, Departments of Nutritional Sciences and Laboratory Medicine and Pathobiology, Mount Sinai Hospital.
Presentation Date: Friday, October 21, 2005
(works in Internet Explorer, but not properly in Firefox (slides don't change in Firefox)).
Fish intake, contaminants, and human health: evaluating the risks and the benefits.
Mozaffarian D, Rimm EB.
JAMA. 2006 Oct 18;296(15):1885-99. Review. Erratum in: JAMA. 2007 Feb 14;297(6):590.
PMID: 17047219
Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer.
Pantuck AJ, Leppert JT, Zomorodian N, Aronson W, Hong J, Barnard RJ, Seeram N, Liker H, Wang H, Elashoff R, Heber D, Aviram M, Ignarro L, Belldegrun A.
Clin Cancer Res. 2006 Jul 1;12(13):4018-26.
PMID: 16818701
Seeram NP, Adams LS, Henning SM, Niu Y, Zhang Y, Nair MG, Heber D.
In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as
Taubert D, Roesen R, Schomig E. Effect of cocoa and tea intake on blood pressure: a meta-analysis. Arch Intern Med. 2007 Apr 9;167(7):626-34. PMID: 17420419 [PubMed - indexed for MEDLINE]
Effects of pistachios on cardiovascular disease risk factors and potential mechanisms of action: a dose-response study.
Gebauer SK, West SG, Kay CD, Alaupovic P, Bagshaw D, Kris-Etherton PM.
Am J Clin Nutr. 2008 Sep;88(3):651-9.
PMID: 18779280
Conclusions/interpretation These results show that the previously demonstrated beneficial effects of these agents on complication-causing pathways in rodent models of diabetic complications also occur in humans with type 1 diabetes.
Oral benfotiamine plus alpha-lipoic acid normalises complication-causing pathways in type 1 diabetes.
Du X, Edelstein D, Brownlee M.
Diabetologia. 2008 Oct;51(10):1930-2. Epub 2008 Jul 29.
PMID: 18663426
DOI: 10.1007/s00125-008-1100-2
Cholesterol is found in every cell of our body. Without it, the body could not make hormones, vitamin D, or the membranes of the cells. In fact, cholesterol is so vital that if you ate none, your body will manufacture it. However, if you don't eat the nutrients your body needs to handle it, then cholesterol can become harmful.
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