Cerebral Palsy

Study to determine whether and how muscle architecture of the quadriceps muscles in cerebral palsy (CP) adapts to two separate training programs: traditional strength training (ST) vs. velocity-enhanced training (VT).

Study and clinical trial being conducted to assess bone growth in children with cerebral palsy

Multi-center study to assess two groups of males and females over the course of their operative treatment for cerebral palsy (CP) scoliosis and the years following that treatment.

Clinic trial to find out if surgery works better than Botulinum Toxin (Botox) injections or regular ongoing treatment (therapy), and if the effects of Botulinum Toxin injections last for longer than six months."

Completed study to assess how often children who are born prematurely and have suffered brain damage, have abnormal appearance of the optic nerve (nerve in the eye) which mimics glaucoma (cupping). This optic nerve cupping is most often seen when children are born after 8 months and is rarely seen in children born before 8 months."

The first comprehensive comparative effectiveness clinical trial of three widely used anti-seizure drugs for childhood absence epilepsy - the most common form of epilepsy in kids - has established an evidence-based approach for initial drug therapy. Published March 4 in the New England Journal of Medicine*, data from the double-blind, randomized, comparative clinical trial fill a large information gap in the treatment of childhood absence epilepsy, also known as "petit mal" epilepsy. The research, which identifies important differences between drugs in seizure control and side effects, is expected to impact how physicians select and monitor initial therapy for children with the disorder and ultimately lead to improved outcomes.

Study will determine the effectiveness, mechanism, and safety of 5 treatments of 6-Hz primed low-frequency rTMS applied to the non-stroke hemisphere and combined with constraint induced therapy (CIT) to promote recovery of the paretic hand.

"The purpose of this study is to obtain preliminary device safety information and demonstrate proof of principle (feasibility of efficacy) of the ability of people with tetraplegia to control a computer cursor and other assistive devices with their thoughts."

Completed Clinical Trial to assess Effect of Power Wheelchairs on the Development and Function of Young Children with Severe Physical Disabilities

"The purpose of this study is to test the effectiveness of a behavioral intervention to promote physical activity adoption over 6 months and maintenance of physical activity over another 6 months by community-dwelling manual wheelchair users."

"The purpose of this study is to collect detailed information about the characteristics and genetics of a large number of individuals with epilepsy"

Study to evaluate where a bedside brainwave monitor can be used to detect early brain injury in premature infants.

This research is designed to look at any additional benefit that may occur when Botox injections are combined with specific occupational therapy exercises and with a device that uses functional electrical stimulation (FES) to help improve muscle function after stroke.

"This multi-center collaborative study will establish a database of information about stroke in infants and children."

The purpose of this research is to develop tools to help people who are paralyzed. These tools are called brain-computer interfaces (BCIs). BCIs would let a person use brain signals to operate technology

"The purpose of this study is to record signatures from the fluid surrounding the spinal cord from people who have an implanted drug infusion system"

"The purpose of this study is to evaluate the effectiveness of botulinum toxin injection to treat drooling in children with cerebral palsy, and to find the most appropriate dosage, duration of effect and side effects."

Research team study to asses ways to measure the stiffness in the joints of hypertonic arms.

Information on completed study to classify types of hypertonia in patients with cerebral palsy and determine if the classifications are reasonable in relation to the functional task of walking."

Planned study to evaluate the impact of a possible new treatment for hypertonia, contributing to the motor disability in children with cerebral palsy (CP)."