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Matti Narkia

MedWire News - Oncology - Vitamin D induces potential breast-tumor suppressor - 0 views

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    MedWire News: Calcitriol, the active form of vitamin D, has been found to induce the tumor-suppressing protein CCAAT enhancer-binding protein (C/EBP)α, which can inhibit the growth of breast cancer cells, researchers report.
Matti Narkia

MedWire News - Oncology - Serum 25(OH)D levels linked to prostate cancer prognosis - 0 views

  • The researchers conclude: “This study shows a strong association between 25(OH)D levels and cause-specific mortality in patients with prostate cancer. The strength of the association indicates that prostate cancer patients can benefit from increasing the level of serum 25(OH)D if it is below 50 nmol/l.”
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    MedWire News: Serum levels of 25-hydroxy vitamin D (25(OH)D) play a role in prostate cancer disease progression and are a potential prognostic indicator, Norwegian study findings suggest.
Matti Narkia

MedWire News - Prostate Cancer - No link between steroid hormones and prostate cancer G... - 0 views

  • “Whether this discrepancy was simply a results of different populations of men in these studies or, more likely, the absence of a consistent biologic relationship, our results suggest that steroid hormones are not a powerful driver of higher grade disease.”
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    MedWire News: Among patients with newly diagnosed prostate cancer, there is no link between circulating steroid hormone levels and Gleason score, conclude US investigators.
Matti Narkia

IL-7/IL-15 increases immune response, inhibits tumor development, metastases - 0 views

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    MedWire News: Intralesional injection of interleukin (IL)-7 and IL-15 enhances the effects of radiofrequency thermal ablation (RFA) in inhibiting tumor development and metastases, animal study results show. RFA, used for the treatment of solid tumors and known for its localized tumor effects, may activate immune responses and thereby reduce the risk for local tumor recurrence or distant metastases through T cell stimulation. However, studies have suggested that additional adjuvant immunotherapy may improve the efficacy of RFA. This preclinical study, reported in Breast Cancer Research and Treatment, was conducted to evaluate the effect of addition of the cytokines IL-7 and IL-15 to RFA in models of breast cancer.
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