It was concluded that omega-3 fatty acid could inhibit the proliferation of pancreatic cancer cell line SW1990 cells and promote their apoptosis. The down-regulation of the cyclin E expression by omega-3 fatty acid might be one of the mechanisms for its anti-tumor effect on pancreatic cancer.
Modulatory effects of EPA and DHA on proliferation and apoptosis of pancreatic cancer cells.
Zhang W, Long Y, Zhang J, Wang C.
J Huazhong Univ Sci Technolog Med Sci. 2007 Oct;27(5):547-50.
PMID: 18060632
Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human colon carcinoma cells.
Habbel P, Weylandt KH, Lichopoj K, Nowak J, Purschke M, Wang JD, He CW, Baumgart DC, Kang JX.
World J Gastroenterol. 2009 Mar 7;15(9):1079-84.
PMID: 19266600