When our body doesn't get enough oxygen, we can become tired and lethargic. We may have difficulty breathing and moving. If the problem is severe enough, we can become dizzy or lose consciousness, and for extreme cases it can lead to death.
It you lack oxygen, the cells in our body would not be supplied with oxygen, this is called Hypoxia. Which means they will get destroyed. This happens within 5~6 minutes after you lack oxygen. When this happens to the brain, your brain cells will get destroyed, causing damages to your brain. After all the brain is the most important part of our body and if all of the brain cells get destroyed eventually we will die.
When you are not able to take enough oxygen, I think that you will get tired because you cannot make energy without oxygen and if it keep, you will die.
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