Varenda cell i kroppen innehåller en biologisk "apparat" som bearbetar och sorterar bland annat proteiner. Den heter Golgi och är unik bland cellens "organ" genom att den faller sönder vid celldelningen. Detta gör Golgi särskilt intressant inom cancerforskning.

Vad händer med golgiapparaten under celldelningen, och finns här några möjliga medicinska angreppspunkter?

After translation on ribosomes in the cytosolic compartment all proteins are processed either in the cytosol or in the ER/Golgi system. 

Endoplasmic Reticulum

Endocytosis is a process for moving items that are outside of the cell into the cytoplasm of the cell. Exocytosis is a process for moving items from the cytoplasm of the cell to the outside. Both endocytosis and exocytosis vary from the other forms of membrane transport, because materials do not cross through the lipid bilayer. Instead, items being moved into or out of the cell are engulfed by entire sections of the membrane lipid bilayer. They are being swallowed up or spit out by the membrane so to speak.

A vesicle is a bubble of liquid within a cell. More technically, a vesicle is a small, intracellular, membrane-enclosed sac that stores or transports substances within a cell. Vesicles form naturally because of the properties of lipid membranes (see micelle). Most vesicles have specialized functions depending on what materials they contain.

Protein Trafficking

Pronunciation Guide

The Golgi Apparatus

Protein Modification (Golgi)

The Golgi apparatus, also called the Golgi complex, is commonly found in eukaryotic cells

The Golgi complex or Golgi apparatus is responsible for manufacturing, warehousing and shipping certain cellular products, particularly those from the endoplasmic reticulum (ER).

The Golgi apparatus (GA), also called Golgi body or Golgi complex and found universally in both plant and animal cells

The Golgi apparatus (also called the Golgi bodies, Golgi complex, dictyosome, or more colloquially Golgi) is an organelle found in most eukaryotic cells. It was identified in 1898 by the Italian physician Camillo Golgi and was named after him.