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Zinc finger, as a miniprotein composed of 26 amino acids, was firstly identified in a transcription study via Xenopus laevis (African clawed frog) and characterized by the coordination of one or more zinc ions in order to stabilize the fold. These proteins are now found with various binding properties which can also bind to DNA, RNA, protein or lipid substrates. Zinc finger is a member of the DNA-binding motifs family, contains multiple finger-like protrusions that can recognize a diverse set of DNA strings in a sequence-specific manner. The binding ability of zinc finger is considered to involve the sequences of finger domains and their linkers, as well as their number and structure order.

In the world of bioscience, Nanobodies (Nbs) or single-domain antibodies are among the smallest and most stable binder scaffolds known by now. In vitro display is a powerful antibody discovery technique used worldwide. Scientists and related institutions are researching so as to make a breakthrough into this field.

Creative Biolabs Anounces De Novo Antibody Sequencing Service for Diagnostic and Therapeutic Use In contrast to other MS based methods, Creative Biolabs is able to discriminate most isobaric amino acid combinations. Read full article at http://www.einpresswire.com/article/271676466/the-role-of-de-novo-antibody-sequencing-in-diagnostics-and-therapy.

Resent years, DNA　immunization technology is quite hot in the field of biotechnology. It has been proved to have great significance in improving the effectiveness of immune procedure. Confronting with this brand new trend of development, pharmaceutical companies are, with different approaches, expanding their business in this realm. Scientists and researchers from Creative Biolabs have developed Direct Antibody Technology™ (DAT) to produce custom polyclonal and monoclonal antibodies. Read full article at http://www.wikigenes.org/e/pub/e/590.html.

On July 1st, Creative Biolabs announced custom scaffold library construction services for Monobody, Adnectin, FN3 or the fibronectin type III domain. Its innovative technology enables the generation of scaffold libraries with desired diversity and high controllability. Scientists of Creative BIolabs developed HiAffi™ platform, which provides an easy and reliable way to build up scaffold libraries and to select potential candidates for use in R&D applications, drug discovery and the development of diagnostic kits. It can be regarded as the foundation of this update service. Read full article at http://www.merchantcircle.com/blogs/Creative.Biolabs.63-187-1580/2015/7/Custom-Scaffold-Library-Construction-Service-in-Research-Applications/1272792.

While doing antibody related research and development, have you ever experienced the difficulty that the majority of the non-human residues in both CDR and FR regions are still immunogenic in humans no matter how hard you've tried? If so, you are sure to get rid of the agony in your next experiment. Read full article at http://www.scienceplease.com/events/creative-biolabs-announces-humanized-antibody-germinalization-service.

"Michael Snyder has taken "know thyself" to the next level-and helped heal thyself. Over a 14-month period, the molecular geneticist at Stanford University in Palo Alto, California, analyzed his blood 20 different times to pluck out a wide variety of biochemical data depicting the status of his body's immune system, metabolism, and gene activity." - From Science Magazine

DNA study links variations in intelligence to large numbers of genes, each with a small effect on individual brainpower Genetic differences between people account for up to half of the variation in intelligence, according to a study of more than 3,000 individuals.

This is one of the best articles I have ever read.