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Vanessa Ward

Maternal levels of dichlorodiphenyl-dichloroethylene (DDE) may increase weight and body... - 0 views

  • Objectives: To investigate the effect of prenatal exposure to polychlorinated biphenyls (PCBs) and dichlorodiphenyl-dichloroethylene (DDE) on weight, height and body mass index (BMI) in adult female offspring of the Michigan fisheater cohort examined between 1973 and 1991
  • Maternal height and BMI were significant predictors of the daughters’ height, weight and BMI.
  • The weight and BMI of adult offspring were statistically significantly associated with the extrapolated prenatal DDE levels of their mothers.
  • ...4 more annotations...
  • ncreasingly, however, prenatal exposure to toxicants is suspected of contributing to obesity.
  • Previous studies have shown that Michigan anglers and fisheaters have higher serum levels of PCBs and DDE than population controls.
  • A total of 176 (82.6%) daughters participated in at least one of two repeated investigations
  • Our results suggest that higher prenatal exposure to DDE, but not to PCBs, is statistically significantly associated with increased weight and BMI in adult female offspring.
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    Liz, this article was already in my library and you might want to look at it. I feel as though the study isn't completely controlled since it deals with people who chose to participate in the study over the course of many years but there are some concepts that can be gathered that may be beneficial to you.
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    This is another epidemiological study similar to the study present by Suphada on sport fish consumption. There were many outside variables, leading to only a small sample size that could be used.
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