Group items tagged

"Major depressive disorder is a common global disease that causes a significant societal burden. Most interventional studies of depression provide a limited assessment of the interventions on mortality and suicide risks. This study utilizes data from an observational registry of patients with major depressive disorder to determine the impact of intervention (vagus nerve stimulation or standard pharmacological/non-pharmacological therapy) and a latent factor, patient trajectory toward response, on mortality, suicide and suicidal ideation. A total of 636 patients were available for an intent-to-treat analysis of all-cause mortality, suicide and suicidal ideation. Patients treated with vagus nerve stimulation in addition to standard therapies experienced lower, but not statistically significant, all-cause mortality (vagus nerve stimulation 4.93 per 1,000 person-years vs. 10.02 per 1,000 patient years for treatment as usual) and suicide rates (vagus nerve stimulation 0.88 per 1,000 person-years vs. 1.61 per 1,000 patient years for treatment as usual). Treatment with vagus nerve stimulation produced a statistically lower relative risk of suicidal ideation 0.80, 95% confidence interval (0.68,0.95). Further, patients that responded to either treatment saw a 51% reduction in relative risk of suicidal behavior; relative risk and 95% confidence interval of 0.49 (0.41,0.58). In summary, we find that treatment with adjunctive vagus nerve stimulation can potentially lower the risk of all-cause mortality, suicide and suicide attempts."

Offered at no cost to participants, the program has enhanced access to treatment, employment, and job training; reduced suicide and self-harm attempts, hospitalizations, emergency department visits, incarcerations, and homelessness; and significantly lowered health care and other mental illness-related costs.

Among the research in collaborative care, the most comprehensive work has been done by Wayne Katon, MD, and Jürgen Unützer, MD, both of the University of Washington. Under the latter's collaborative care model, participants had fewer suicidal thoughts, higher recovery rates and improved function, and more depression-free days compared to typical primary care treatment. In addition, Unützer's research has shown potential overall health care savings of $3,300 per individual over a four-year period compared to individuals in usual primary care treatment.

From a sample of Florida patients (abstract)

from the introduction: "his progress report outlines advances made to date to expand the quality and availability of mental health care services for active military service members, veterans, and their families. Highlights of the report include: Increasing the capacity of the Veterans Crisis Line Building partnerships between the VA and community-based mental health providers Increasing the number of VA mental health providers and peer specialists Implementing a national suicide prevention campaign."

A husband tells the story of his spouse's sudden onset of severe mental illness, how he supported her through it and about his own coping mechanisms, as well as perspective gained upon reflection