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Graeme Wadlow

Randomized, Controlled Trial of an Intervention for Toddlers With Autism: The Early Sta... - 0 views

pediatrics.aappublications.org/...e17

RP1 autm Pediatrics Randomised Control Trials toddlers autism ASD Early Start Denver Model

shared by Graeme Wadlow on 04 Jan 12 - No Cached
  • Graeme Wadlow on 04 Jan 12
     
    Randomized, Controlled Trial of an Intervention for Toddlers With Autism: The Early Start Denver Model
Tero Toivanen

Autism Research Blog: Translating Autism: Expressive communication in children with sev... - 0 views

www.translatingautism.com/...communication-in-children.html

autism expressive communication severe autism low functioning autism

shared by Tero Toivanen on 02 Apr 09 - No Cached
  • Given that the rate of elicited expressive communication in the present study is much lower than the suggested rate of teacher prompt, it can be assumed that teachers of students with autism do not actively promote their students’ expressive communication.
  • The results also indicate that verbal prompts and a combination of verbal prompts and modeling were the most commonly used instruction. However, simple (non-combined) prompts were most effective in eliciting a communicative response with kids with the most severe autism. But most surprisingly, physical prompts did not seem to be as effective as verbal prompts, which may also explain why verbal prompts were use significantly more by these teachers.
  • In sum, the study has implications for the type of techniques that are effective in eliciting communicative responses in children with severe autism. In this study simple verbal prompts and modeling were the most effective strategy to elicit communicative responses in these children.Chiang, H. (2009). Naturalistic observations of elicited expressive communication of children with autism: An analysis of teacher instructions Autism, 13 (2), 165-178 DOI: 10.1177/1362361308098513
  • Tero Toivanen on 02 Apr 09
     
    In sum, the study has implications for the type of techniques that are effective in eliciting communicative responses in children with severe autism. In this study simple verbal prompts and modeling were the most effective strategy to elicit communicative responses in these children.
Tero Toivanen

Helping Autistic children learn with Video Modeling techniques | Emerging Internet Tech... - 0 views

www.emergingedtech.com/...with-video-modeling-techniques

autism video Video Modeling Technology

shared by Tero Toivanen on 27 Jan 10 - Cached
  • Tero Toivanen on 27 Jan 10
     
    An inspiring use of technology, helping students challenged with Autism and similar disorders.
Tero Toivanen

Journal of Neuropsychiatric Disease and Treatment - Dove Press - 0 views

www.dovepress.com/b-acute--peer-reviewed-article

shared by Tero Toivanen on 16 Mar 09 - Cached
  • Increasing evidence has shown that, in animal stroke models, administering melatonin significantly reduces infarct volume, edema, and oxidative damage and improves electrophysiological and behavioral performance.
    • Tero Toivanen
      Tero Toivanen on 16 Mar 09
       
      Melatonin also improves behavioral performance.
  • Given that melatonin shows almost no toxicity to humans and possesses multifaceted protective capacity against cerebral ischemia, it is valuable to consider using melatonin in clinical trials on patients suffering from stroke.
Tero Toivanen

Google-syötteenlukija (4) - 0 views

www.google.com/view

autism google SketchUp 3D skills

shared by Tero Toivanen on 29 Aug 09 - Cached
  • Tero Toivanen on 29 Aug 09
     
    Google had a booth at the Autism Society of America conference last month so they could show off their free software program SketchUp. SketchUp was originally developed for users to create, modify and share 3D models. Turns out SketchUp helps folks with autism develop some skills, too.
Tero Toivanen

Easter Seals and Autism » Blog Archive » What does Google have to do with ... - 0 views

autismblog.easterseals.com/ism-check-out-sketchup-and-see

google autism 3D skills SketchUp

shared by Tero Toivanen on 29 Aug 09 - Cached
  • Tero Toivanen on 29 Aug 09
     
    Google had a booth at the Autism Society of America conference last month so they could show off their free software program SketchUp. SketchUp was originally developed for users to create, modify and share 3D models. Turns out SketchUp helps folks with autism develop some skills, too.
Tero Toivanen

Early intervention for toddlers with autism highly effective, study finds - 1 views

www.physorg.com/news178781035.html

autism toddlers study IQ language ability social interaction

shared by Tero Toivanen on 17 Dec 09 - Cached
  • The study, published online today in the journal Pediatrics, examined an intervention called the Early Start Denver Model, which combines applied behavioral analysis (ABA) teaching methods with developmental 'relationship-based' approaches.
  • The five-year study took place at the University of Washington (UW) in Seattle and was led by Dawson, then a professor of psychology and director of the university's Autism Center, in partnership with Rogers. It involved therapy for 48 diverse, 18- to 30-month-old children with autism and no other health problems.
  • At the conclusion of the study, the IQs of the children in the intervention group had improved by an average of approximately 18 points, compared to a little more than four points in the comparison group. The intervention group also had a nearly 18-point improvement in receptive language (listening and understanding) compared to approximately 10 points in the comparison group. Seven of the children in the intervention group had enough improvement in overall skills to warrant a change in diagnosis from autism to the milder condition known as 'pervasive developmental disorder not otherwise specified,' or PDD-NOS. Only one child in the community-based intervention group had an improved diagnosis.
  • ...2 more annotations...
  • In this study, the intervention was provided in a toddler's natural environment (their home) and delivered by trained therapists and parents who received instruction and training as part of the model.
  • Parents are taught strategies for capturing their children's attention and promoting communication. By using these strategies throughout the day, the children were offered many opportunities to learn to interact with others.
  • Tero Toivanen on 17 Dec 09
     
    A novel early intervention program for very young children with autism - some as young as 18 months - is effective for improving IQ, language ability, and social interaction, a comprehensive new study has found.
Tero Toivanen

A week ago, a new study published in the Archives of General - 0 views

www.theautismnewswire.com/NewsITems.aspx

study autism research gene mutation ASD sporadic spectrum disorders de novo spontaneous mutations intellectual disability epilepsy

shared by Tero Toivanen on 22 May 11 - No Cached
  • The Howard Hughes Medical Institute describes how researchers using "high-throughput gene sequencing technology" were able to identify several de novo or spontaneous gene mutations in 20 children with sporadic autism spectrum disorders -- that is, their family members showed no other sign of autism.
  • The team identified 21 spontaneous mutations -- meaning they weren't inherited from either parent -- in the children's DNA. Eleven of these were mutations that would alter the protein encoded by the affected gene. In four of the 20 children, the researchers found mutations that were severe, some of which have been previously linked to autism, intellectual disability, and epilepsy.
  • one child had a mutation in the GRIN2B gene, which is crucial for neuronal signaling.
  • ...3 more annotations...
  • Another individual had an extra nucleotide in FOXP1, a gene that, along with its close relatives, has been heavily implicated in language defects.
  • These new findings support the 'multi-hit' model of autism, which suggests that having more than one mutation can cause or worsen symptoms of autism and other brain disorders. The different combinations of mutations may contribute to the heterogeneity in ASDs.
  • That such different combinations of genetic mutations contribute to a child being autistic could account for why individuals with an ASD diagnosis have some very similar, and very different, features.
  • Tero Toivanen on 22 May 11
     
    "The Howard Hughes Medical Institute describes how researchers using "high-throughput gene sequencing technology" were able to identify several de novo or spontaneous gene mutations in 20 children with sporadic autism spectrum disorders -- that is, their family members showed no other sign of autism."
Tero Toivanen

NeuroLogica Blog » The Genetics of Autism - 0 views

www.theness.com/neurologicablog

autism genetics

shared by Tero Toivanen on 03 May 09 - Cached
  • What this means is that there is likely to be a complex set of many factors that contribute to ASD - not one single cause.
  • The same exact situation is true for other entities, like schizophrenia and attention deficit disorder (ADD).
  • One difference, however, is that schizophrenia and ADD likely represent changes to particular parts of the brain, while autism is likely due to changes in the global architecture of the brain.
  • ...5 more annotations...
  • Getting back to the genetics of autism, current models are therefore consistent with what is being found when the genetics of autism is researched - researchers are finding many genes that predispose to autism in a subset of cases but no single or simple universal cause. At present, 133 different gene variants have been linked to autism.
  • This new research, conducted by Dr. Hakon Hakonarson of the Children’s Hospital of Philadelphia, is a genome wide analysis involving about 10,000 individuals.
  • The results are especially significant because the variants lie between two genes, called CDH9 and CDH10, which are known to play an important role in forming nerve connections in the brain.
  • The gene variants that correlated with ASD are for proteins that are involved in the process of neurons forming connections with each other. There is already other lines of evidence that suggest what is different in ASD brains is a decrease in the amount of interconnectedness and communication among neurons. It is therefore likely no coincidence that this study found genetic correlations for proteins involved with neuronal connections.
  • This also is compatible with the finding that many separate genes are potentially involved with ASD - for there are many separate genes and processes involved with forming and maintaining neuronal connections.
  • Tero Toivanen on 03 May 09
     
    A new genome-wide analysis of families with autism has found significant gene associations, adding to the growing evidence for strong genetic contribution to autism.
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