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Danila Medvedev

Category:Aging - Wikipedia, the free encyclopedia - 0 views

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    Статьи в Википедии. Надо как-то изучить и классифицировать. Возможно, раскидать по разным разделам, чтобы использовать это там.
Danila Medvedev

Aging Watch at the UN : Global Action on Aging - 0 views

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    Интересно, какую роль играет в ООН эта организация. Как это можно использовать и как это может помешать.
Danila Medvedev

Global Action on Aging - 0 views

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    Изучить. Есть русская версия. Один из крупнейших сайтов по старикам.
Danila Medvedev

Профилактика старения ~ Профилактика старения ~ Заглавная страница - 0 views

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    Русский журнал, выложены некоторые статьи.
Danila Medvedev

Типичный международный научный проект и его организация. - 0 views

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    Образцовый пример научной организации. Не в том смысле, что все очень круто, а в том, что все типично.
Danila Medvedev

NIH Roadmap - Overview - 0 views

  • The initial step in the Roadmap process involved a series of five meetings in which Dr. Zerhouni and Directors of the various NIH Institutes and Centers led invited participants through lively discussions
  • The priority areas identified through the Roadmap meetings formed the basis for discussions held at the 2002 NIH Leadership Forum
  • What are today's scientific challenges? What are the roadblocks to progress? What do we need to do to overcome roadblocks? What can't be accomplished by any single Institute
  • ...9 more annotations...
  • What can be done? What can't be done? What needs to be done? When can it be done? What is realistic?
  • new ideas were further refined
  • systematic analysis and planning
  • Working Groups of NIH staff, along with ad hoc outside advisors, were formed
  • Each working group presented their top initiatives
  • Is the initiative truly transforming—will it dramatically change how or what biomedical research is conducted in the next decade? Would the outcomes from the initiative be used by and synergize the work of many NIH Institutes and Centers? Can the NIH afford NOT to do it? Will the initiative be compelling to our stakeholders, especially the public?
  • The Roadmap working groups were grouped into nine Implementation Groups
  • implementation plans
  • timelines, milestones, mechanisms for coordination, need for inventories, and staffing needed for program implementation
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    Сокращённый вариант включить в раздел по дорожным картам.
Danila Medvedev

...Жили они долго. И счастливо? Проблемы геронтологии и гериатрии - 0 views

  • И если вынести за скобки насильственные смерти, в том числе от несчастных случаев, то преждевременно мы умираем потому, что ускоренно стареем. Для России вообще характерно биологическое старение людей, которые официально еще не считаются пожилыми.
    • Danila Medvedev
       
      демография
  • Именно применение пептидных биорегуляторов-геропротекторов стало основой программы. Программа на 2008 – 2015 гг., повторим, сейчас обсуждается в Академии медицинских наук и уже прошла обсуждения и экспертизу в Общественной палате РФ. По словам профессора Хавинсона, ООНовский департамент по старению охарактеризовал программу как «единственную реальную, доступную финансово систему по сохранению здоровья и повышению качества жизни лиц пожилого и старческого возраста».
    • Danila Medvedev
       
      Программа Хавинсона
Danila Medvedev

Overcoming Bias: FHI Emulation Roadmap Out - 0 views

  • In order to develop ideas about the feasibility of WBE, ground technology foresight and stimulate interdisciplinary exchange, the Future of Humanity Institute hosted a workshop on May 26 and 27, 2007, in Oxford. Invited experts from areas such as computational neuroscience, brain‐scanning technology, computing, and neurobiology presented their findings and discussed the possibilities, problems and milestones that would have to be reached before WBE becomes feasible.
  • This document combines an earlier whitepaper that was circulated among workshop participants, and additions suggested by those participants before, during and after the workshop. It aims at providing a preliminary roadmap for WBE, sketching out key technologies that would need to be developed or refined, and identifying key problems or uncertainties.
  • This report is a major milestone, a detailed summary of the state of the art
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    Эмуляция мозга
Danila Medvedev

Practical Ethics: Why We Need a War on Aging - 0 views

  • Anti-aging research is scandalously under-funded.  In the US, a vast proportion of the funding doled out by the National Institute of Aging is given to research on Alzheimer's disease. According to one estimate (from circa 2004), only about 0.02% of the money spent by the National Institutes of Health (of which the NIA is part) is spent on fundamental aging research.
    • Danila Medvedev
       
      Финансирование фунд. исследований (непонятно, чья оценка)
  • The more we understand about the biochemical processes involved in senescence the more we find that they look like disease processes. The accumulation of lysosomal aggregates and amyloid plaques, extracellular protein-protein cross-linking, nuclear and mitochondrial mutations, cell atrophy, cell senescence, and cell loss without replacement: these processes may all be implicated in both pathology and senescence.   At the level of genetics and biochemistry, there simply does not seem to be any meaningful distinction between "processes predisposing to or constituting disease" and "normal aging".
    • Danila Medvedev
       
      Современное понимание
  • Aging is not an evolutionary adaptation. Aging, rather, is what happens when various bodily systems evolved to maintain health gradually accumulate defects and begin to malfunction. In the Pleistocene, when life-expectancy is estimated to have been a mere 20 years, too few of our ancestors survived to ripe old age for evolution to favor investment in stronger anti-aging defenses than those we now possess and are forced to rely upon, notwithstanding their evident inadequacy in the modern era where many causes of premature death have been removed.
    • Danila Medvedev
       
      Современное понимание
Danila Medvedev

Aging Research Network-Rationale - 0 views

  • There are two aspects to aging which most will recognize, the chronological passage of time which we associate with the benefits of increased experience and wisdom, and the increasing levels of dysfunction we experience as we get older.  One is welcome, the other less so.
  • It is estimated that 80% of our health care dollars go to the treatment of age-related dysfunction.  The Miliken Institute reported in Oct 2007 that in 2003 it cost 1.3 TRILLION DOLLARS per year in direct and indirect costs ameliorate the suffering of the aged. This is in stark contrast to the 150-200 Million Dollars actualy spent on studying aging which amounts to 1/6th of 1 percent of the yearly budget of the National Health Institute of 28 Billion dollars.
    • Danila Medvedev
       
      это в финансирование
  • The reason for this disproportionate focus on spending on dysfunction instead of research is that aside from healthy lifestyle choices, little can presently be done to intervene in the aging process and people tend to disbelieve that serious progress will ever be made in addressing the dysfunction that accompanies the aging process.  Due to new breakthroughs this overly-pessimistic perspective is slowly changing.
    • Danila Medvedev
       
      наверное в научные возможности вмешательства
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  • The chart to the right describes the aging process from the point of view of increasing dysfunction and the different ways in which medicine and science try to deal with it
    • Danila Medvedev
       
      часть нашей схемы. идет в современное понимание старения.
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    в современное понимание старения. есть небольшая схема, которая интегрируется с моей схемой про смерть.
Danila Medvedev

LifeStar Project-Contact - 0 views

  • William Millard - Chairman Founder and former chairman of ComputerLand Corporation with ultimately over 800 stores in 28 countries.
    • Danila Medvedev
       
      основатель проекта Life Star
Danila Medvedev

Aging Research Network-Aging Research Network - 0 views

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    Ничего не решающая "сеть" по старению. Возглавляет её Кевин Перро, ранее в Фонде Мафусаила и M-Prize, сейчас в Life Star.
Danila Medvedev

LifeStar Project-Advisors - 0 views

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    советники проекта Life Star. в основном по биологии и геронтологии.
Danila Medvedev

LifeStar Project-Resources - 0 views

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    Возможности вмешательства, экономика и демография старения. Целый ряд интересных документов, которые можно использовать при составлении обзора.
Danila Medvedev

LifeStar Project-LifeStar World Health Star Initiative (LSWHI) - 0 views

  • What is needed - and does not yet exist - is a concerted, focused, competent, and fully-funded effort to finish the development of the complete set of therapies and protocols that will prevent the occurrence of the diseases of aging.
Danila Medvedev

Wellcome Trust Heart Physiome Project - 0 views

  • This project is part of a wider umbrella program, the Physiome Project .
    • Danila Medvedev
       
      Утверждается, что этот проект - часть первого физиома
Danila Medvedev

The IUPS Physiome Project - IUPS Physiome Project - 0 views

  • The Physiome Project is a worldwide public domain effort to provide a computational framework for understanding human and other eukaryotic physiology.
  • integrative models at all levels
  • ontologies
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  • markup languages
  • databases
  • software
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    ориентирован на компьютерную часть
Danila Medvedev

STEP Home Page - 0 views

  • Europhysiome Initiative
  • STEP coordination action
  • All valuable resources were moved to the VPH Square
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  • The call for proposal entitled Virtual Physiological Human should be out in days. It should call for proposals up to 76 Million Euro of EC support
  • Last, but not least, the World Integrative Research Initiative folder contains the WIRI Agreement. This is a expression of good will that integrative research projects are signing, so as to have a shared agenda, but also to demonstrate that we are worldwide community. If you want your consortium to subscribe this agreement, please write to me directly.
  • Marco Viceconti STEP, Scientific Coordinator
Danila Medvedev

NIH Roadmap for Medical Research - 0 views

  • These are programs that might not otherwise be supported by the NIH ICs because of their scope or because they are inherently risky. Roadmap Programs are expected to have exceptionally high potential to transform the manner in which biomedical research is conducted. They are also expected to be short term, 5–10 year programs. This “incubator space” time frame is intended to allow the major roadblocks that were defined for each program to be overcome, thereby stimulating further research conducted through the ICs.
    • Danila Medvedev
       
      Теоретически подобный формат может подойти для нас в США
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    Это НЕ дорожные карты
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