In this blog post by a Microsoft developer, there are examples of scrolling on a single webpage by moving left to right (vs. scrolling up and down). Also, some main navigational buttons and menus are now on the RIGHT side of the layout instead of the long-used left side of the layout location for these elements.
I believe this is an example of the influence of touch screens on tablets, phones, and computers affecting the long held paradigm of left side menu navigation. The gesture navigation of touch screens is making another mark on design and layouts.
This is a really sleek looking top-layer framework specific for mobile touch interaction. The Art of Manliness just launched their new website, I suggest visiting http://artofmanliness.com on both your desktop and iPad to see the difference.