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There is currently no cure. The disease is caused by gene mutations that disrupt production of the protein prelamin A, found inside the nuclei of cells. The damaged prelamin A binds to molecular fragments in the body called farnesyls, which then bind to the nuclear membrane, causing the build-up of protein that underlies the disease. The quote basically says that the disease had no cure yet and it is caused by gens mutation. It also says how but i don't fully understand it.