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Casey Finnerty

To Fight a Virus, Get a Virus: Military Bets on Mutant Pathogen - Bloomberg - 1 views

www.bloomberg.com/...nfections-in-two-brothers-labs

shared by Casey Finnerty on 15 Jul 16 - No Cached
  • Casey Finnerty on 15 Jul 16
     
    Describes the use of therapeutic interfering particles to treat viral disease.
Casey Finnerty

Google Builds a New Tablet for the Fight Against Ebola | WIRED - 0 views

www.wired.com/...-builds-new-tablet-fight-ebola

ebolavirus

shared by Casey Finnerty on 02 Apr 15 - No Cached
  • Casey Finnerty on 02 Apr 15
     
    Neat intersection of virology, medicine and technology.
Sarah Muncy

The HIV Virus: A Possible Cure for Leukemia? | Yahoo! Health - 0 views

health.yahoo.net/...v-virus-possible-cure-leukemia

shared by Sarah Muncy on 12 Dec 12 - No Cached
  • It's important to note that the T-cells are removed from the patient before being bioengineered with the HIV virus
    • Sarah Muncy
      Sarah Muncy on 12 Dec 12
       
      Why is it important to note that the disabled virus isn't injected into the patient? It's function isn't like chemotherapy at all- why even make the comparison?
    • Sarah Muncy
      Sarah Muncy on 12 Dec 12
       
      Is there some reason they use T cells only? Are they trying to target T cells, but not dendritic cells or macrophages?
  • therapies that involve the reprogramming of a patient’s immune system, may also eventually be used to fight cancerous breast and prostate tumors.
    • Sarah Muncy
      Sarah Muncy on 12 Dec 12
       
      What about lupus, or even allergies for that matter?
  • ...1 more annotation...
  • Within hours
    • Sarah Muncy
      Sarah Muncy on 12 Dec 12
       
      Within hours?!
  • Sarah Muncy on 12 Dec 12
     
    Whoa. If someone is doing HIV- this may be helpful. The virus is being used as a delivery device for genetics to reprogram lymphocytes. They're like biological nanorobots.
Casey Finnerty

Dr. Donald A. Henderson, Who Helped End Smallpox, Dies at 87 - The New York Times - 1 views

www.nytimes.com/...d-end-smallpox-dies-at-87.html

smallpox vaccine

shared by Casey Finnerty on 22 Aug 16 - No Cached
  • Dr. Donald A. Henderson, a leader of one of mankind’s greatest public health triumphs, the eradication of smallpox, died on Friday in Towson, Md. He was 87.
  • died in a hospice of complications of a hip fracture, including infection with antibiotic-resistant staphylococcus, a dangerous pathogen he had himself researched and raised alarms about
  • The last known case was found in a hospital cook in Somalia in 1977.
  • ...14 more annotations...
  • The only other disease to have been banished from the earth is rinderpest, a little-known relative of measles that kills hoofed animals and once caused widespread starvation in Africa; it was eradicated in 2011.
  • Smallpox, caused by the variola virus, was long one of mankind’s most terrifying scourges.
  • it killed almost a third of its victims, often through pneumonia or brain inflammation.
  • Many others were left blind from corneal ulcerations or severely disfigured by pockmarks.
  • Because it killed 80 percent of the American Indians who caught it, it was a major factor in the European conquest of the New World.
  • In 1796, Dr. Edward Jenner, an English physician, infected a young boy with cowpox taken from a blister on a milkmaid’s hand. Cowpox, a mild disease, protected those who had it from smallpox, and the modern vaccine era began.
  • Dr. Henderson quickly realized that trying to vaccinate vast populations was futile and switched to “ring vaccination.”
  • Dr. Foege, who is considered the father of this tactic, said it was “invented by accident” during a 1967 Nigerian outbreak when he had very little vaccine on hand.
  • “The first night, we asked ourselves what we would do if we were a virus bent on immortality,”
  • In 1977, success in hand, Dr. Henderson became dean of the Johns Hopkins University School of Hygiene and Public Health.“He was an imposing guy — physically big and very confident,” said Dr. Michael J. Klag, the school’s current dean, who was a student in that era. “He did not suffer fools gladly, and you were never sure if you were a fool or not.”
  • He gloomily foresaw failure for most other disease-elimination campaigns. The “siren song of eradication,” he once wrote, had led to goals that were more “evangelical” than attainable.
  • The problem, he would explain, was that each viral foe was so different. Smallpox had many weaknesses to exploit; it had no animal host. Every case can be found because victims have pox on their faces, and one vaccination provides lifetime immunity.
  • In 2011, when Bill Gates threw the full weight of his foundation into fighting polio, he struggled to explain how he would overcome such obstacles and, at the end of an interview, turned to an aide and said aloud, “I’ve got to get my D. A. Henderson response down better.”
  • The campaign, many experts have noted, succeeded just in time. A few years later, the virus that causes AIDS spread across Africa. Because the live smallpox vaccine can grow in an immune-compromised person into a huge, rotting, ultimately fatal lesion, it would have been impossible to deploy it.
Casey Finnerty

Obama Presses Leaders to Speed Ebola Response - NYTimes.com - 0 views

www.nytimes.com/...to-bolster-ebola-response.html

ebolavirus

shared by Casey Finnerty on 17 Sep 14 - No Cached
  • On Tuesday night, administration officials said the Pentagon would ask Congress to redirect $500 million from existing Defense Department funds to fight Ebola. The money is in addition to $500 million the Pentagon requested last week in redirected funds for both Iraq and Ebola.
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