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Casey Finnerty

Functional importance of deletion mut... [Appl Environ Microbiol. 2005] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...16085811

virology baculoviruses genomics population biology genetics

shared by Casey Finnerty on 25 Sep 12 - No Cached
  • Casey Finnerty on 25 Sep 12
     
    This paper shows the importance of genotypic diversity for baculovirus populations, particularly in terms of pathogenicity.
Casey Finnerty

Quasispecies diversity determines pathogenesis throug... [Nature. 2006] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...16327776

virology genomics population biology genetics

shared by Casey Finnerty on 25 Sep 12 - No Cached
  • Analysis of viruses isolated from brain provides direct evidence for complementation between members in the quasispecies, indicating that selection indeed occurs at the population level rather than on individual variants.
Casey Finnerty

Cooperative interactions in the West Nile virus mutant swarm - 0 views

www.ncbi.nlm.nih.gov/...PMC3358237

virology population biology genomics genetics

shared by Casey Finnerty on 25 Sep 12 - No Cached
  • In addition, our data demonstrate that increasing levels of co-infection can lead to widespread strain complementation, which acts to maintain high levels of phenotypic and genetic diversity and potentially slow selection for individual variants. Lastly, we show that cooperative interactions may lead to swarm fitness levels which exceed the relative fitness levels of any individual genotype.
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