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Contents contributed and discussions participated by Alison Prodzinski

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Coccidioidomycosis: Host Response and Vaccine Development - 0 views

cmr.asm.org/...804.short
shared by Alison Prodzinski on 24 Apr 13 - No Cached
  • Alison Prodzinski on 24 Apr 13
     
    Excellent paper that focuses on vaccination of coccidoidomycosis. Used for our presentation.
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Progress Toward a Human Vaccine Against Coccidioidomycosis - Springer - 1 views

link.springer.com/...10.1007%2Fs12281-012-0105-y
shared by Alison Prodzinski on 24 Apr 13 - No Cached
  • Alison Prodzinski on 24 Apr 13
     
    Excellent paper about the progress towards vaccination of Coccidodiomycosis. Used for our presentation.
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Signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations a... - 0 views

www.sciencedirect.com/...S0091674913002650
shared by Amy Jorgenson on 24 Apr 13 - No Cached
  • Alison Prodzinski on 24 Apr 13
     
    This paper does an excellent job researching the correlation of the methylation of the STAT-1 gene and genetic mutations in coccidiodiomycosis and histoplasmosis. The paper shows evidence of the methylation of the STAT-1 by the PIAS1 protein. This gene mutation immunologically challenges the IFN-γ and alters the body's defense mechanisms. Excellent paper on a very scary disease. Hopeful for a vaccine!!! 
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Coccidioidomycosis-A Fungal Disease of the Americas - 0 views

www.ncbi.nlm.nih.gov/...PMC545195
shared by Amy Jorgenson on 24 Apr 13 - No Cached
  • Alison Prodzinski on 24 Apr 13
     
    This paper is an overview of Coccidioidomycosis. The explains the demographics, the life cycle, history, immunology, and treatment. The hope for a vaccine is also prevalent in this paper.  The paper summarizes Coccidioidomycosis and gives quick details about it.  Excellent paper on learning about the disease without diving in too deeply.
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http://web1.cnre.vt.edu/korine/offprints/Kolivras_etal_Aerobio01.pdf - 0 views

web1.cnre.vt.edu/...Kolivras_etal_Aerobio01.pdf
shared by Alison Prodzinski on 24 Apr 13 - No Cached
  • Alison Prodzinski on 24 Apr 13
     
    The living conditions of Coccidioidomycosis (Valley Fever) are endemic to the Western Hemisphere. This paper explains the conditions of which the coccidioides is the happiest. 
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Brain Scans Offer Precise Measurement Of Human Pain | Popular Science - 0 views

www.popsci.com/...-accurate-measure-burning-pain
shared by Alison Prodzinski on 11 Apr 13 - No Cached
  • Further research along these lines could lead to an objective measure of physical pain, though that's still a long ways away.
  • Right now, if a doctor wants to measure or record someone's pain, she'll generally just ask her patient about it, or ask her patient to rate his pain from 1 to 10. That will always be a very important part of diagnosis, Wager says, but having a less subjective measure could nevertheless help. Some people, such as very young, very old or certain disabled people, can't communicate well. Others may underreport their pain—or are less likely to be believed.
  • Using this pain signature, they were then able to evaluate people's pain in response to particular levels of heat with 90 to 100 percent accuracy
  • Alison Prodzinski on 11 Apr 13
     
    Pain is exactly that - no matter what kind! Pain from sunburn or pressure initiates the same pain... Researchers will be using this to test how much pain they have. Using the research that they have found, they will be able to deduce how much pain a person is in!!
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Bathing, but Not Alone - NYTimes.com - 0 views

www.nytimes.com/...15shower.html
shared by Alison Prodzinski on 08 Apr 13 - No Cached
  • Another paradox of city life: it seems it is healthier to inhale the subway’s air than the shower’s mist.
  • the deluge of bacteria that hit your face and flow deep into your lungs in the morning shower
  • Running the water for 30 seconds before stepping in would mean fewer bacteria in one’s face
  • ...3 more annotations...
  • Aside from the thought of being sprayed in the face by a bacterial cocktail every morning, the shower bacteria present no serious danger
  • the subway air is remarkably fresh and like outdoor air
  • Another paradox of city life: it seems it is healthier to inhale the subway’s air than the shower’s mist.
  • Alison Prodzinski on 08 Apr 13
     
    Bacteria are everywhere - including the shower!! There are 15 different kinds of bacteria that live in the shower -- they get into your lungs via inhalation and your skin. These bacteria are not all bad though - only Mycobacterium avium - it can cause chest complaints and issues. Research on the shower and bacteria was then compared to a New York City subway - in which the subway was healthier then the shower! WOW!! However, hope is not lost - researchers said to run the shower for 30 seconds and most bacteria will be gone!!
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The Flu Virus Can Tell Time. Here's Why You Should Care | Popular Science - 0 views

www.popsci.com/...time-heres-why-you-should-care
shared by Alison Prodzinski on 02 Apr 13 - No Cached
  • Influenza can tell time, and it choreographs its actions according to a strict schedule.
  • The virus has to orchestrate its actions carefully--if it moves too fast, it won’t have time to make new copies of itself, and if it moves too slowly, it might be stopped by immune defenses.
  • To fight it, they tricked the virus into changing the amount of time it took to gather the protein. First, they made it acquire the protein too quickly, which caused the flu to leave the cell before it had made enough copies of itself. In this case, the cells were lung epithelial cells. Then they altered it to leave too late, giving immune cells enough time to respond and kill the virus before it escaped.
  • Alison Prodzinski on 02 Apr 13
     
    Viruses are smarter then we ever imagined!! Researchers have realized that virus have their own time-clock. Virus's take about 8 hours to sufficiently make copies and overtake our bodies. They slowly build in our bodies, before the body actually realizes what is happening - by that time it is too late. Researchers are now tricking viruses into changing the time needed to overtake the body - making the body react quicker and kill the virus. The flu vaccine is still the best way, however, if we can fool the time it takes for a virus to overthrow the body - can we stop it in general? 
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How Pigs on Antibiotics Are Making Superbugs Stronger | Popular Science - 0 views

www.popsci.com/...-are-making-superbugs-stronger
shared by Alison Prodzinski on 28 Mar 13 - No Cached
  • new research suggests it’s the animals, and the drugs we feed them
  • MRSA started out as a drug-defeatable bug and then transferred into the pig population, where it developed resistance to two common forms of antibiotics
  • “[It’s] like watching the birth of a superbug,”
  • ...1 more annotation...
  • humans have supplied a strong force through the excessive use of antibiotic drugs in farm animal production,
  • Alison Prodzinski on 28 Mar 13
     
    MSRA could be defeated when first discovered. However, it was transferred to the pig population and went crazy after that. Humans over immunize animals and make super-bugs from inappropriate and overuse of antibiotics.  New tests are being done with bacteria being injected into other hosts - which then can be used to kill MRSA. This method could find new and natural antibiotics that could fight various forms of drug-resistant superbugs!
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Brand-New Vaccine Strategy Works Against Herpes, And Potentially HIV | Popular Science - 0 views

www.popsci.com/...rpes-and-may-do-whole-lot-more
shared by Alison Prodzinski on 28 Mar 13 - No Cached
  • The Yale team’s “prime and pull” method is focused on exactly that. Working with mice, the researchers found a way to “prime” T cells to fight a certain kind of infection
  • through conventional vaccination that causes a system-wide immune response.
  • The “prime and pull” technique could potentially be used to combat any infectious agent that enters the body through any specific tissue--agents like the human immunodeficiency virus (HIV) that causes AIDS.
  • Alison Prodzinski on 28 Mar 13
     
    Manipulating T-Cells to fight certain infections, then pulling them out of the body as to not harm anything - because they can spread nasty diseases in places like the central nervous system.  They are now testing these T-cells against HIV. This could be revolutionary - in that the 'Prime and Pull' method could be used over and over without harming the person.  Just proof of how cool T-cells are!! Both useful and harmful if used inappropriately.
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16,000 Dead Pigs In The Huangpu: Can You Still Drink Shanghai's Water? | Popular Science - 1 views

www.popsci.com/...lly-still-drink-water-shanghai
shared by Alison Prodzinski on 27 Mar 13 - No Cached
  • Alison Prodzinski on 27 Mar 13
     
    The dead pigs are being thrown into the water, not dying from the water. After being dumped in, they are becoming toxic in the river and emitting poison into the water.  The city of Shanghai relies on the river for the all the drinkable water in the city.  City officials have no idea how toxic the river has become, since no studies were done prior to the findings.  More research showed that the pigs are being dumped into the river because of costs of discarding the dead animal. It is cheaper to dump it, even though it could be toxic to the whole city.  Makes you wonder - we eat dead animals. But, when dumped in drinking water, they become toxic.... Hmmm.....
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Nearly 200 sick at cheerleading competition - Vitals - 0 views

vitals.nbcnews.com/...ck-at-cheerleading-competition
shared by Alison Prodzinski on 22 Mar 13 - No Cached
  • Alison Prodzinski on 22 Mar 13
     
    This puts a whole new light on 'spirit'!!! Sterilization is SO important!!! Other articles are saying that this competition and the arena -- "It's probably the best-scrubbed place in the county," she added. Cheerleading camps or competitions have been the source of previous outbreaks, including a 2002 E. coli O157:H7 outbreak in Eastern Washington. This is crazy!!! Person to person contact is inevitable in cheerleading camps and competition. Proves how important sterilization and handwashing is!!!
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Belly Button Biodiversity - 1 views

www.wildlifeofyourbody.org
shared by Alison Prodzinski on 24 Jan 13 - No Cached
  • Alison Prodzinski on 24 Jan 13
     
    I was thinking of this after culturing my belly button..... 
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