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hat urgency is at odds with the stance of the Trump administration, which has rolled back several Obama-era environmental regulations and incentivized the production of fossil fuels. Trump also has said he plans to withdraw the nation from the Paris climate accord and questioned the science of climate change just last month, saying on CBS’s “60 Minutes” that “I don’t know that it’s man-made” and that the warming trend “could very well go back.”

“This report draws a direct connection between the warming atmosphere and the resulting changes that affect Americans' lives, communities, and livelihoods, now and in the future,” the document reads, concluding that “the evidence of human-caused climate change is overwhelming and continues to strengthen, that the impacts of climate change are intensifying across the country, and that climate-related threats to Americans' physical, social, and economic well-being are rising.

The report finds that the continental United States already is 1.8 degrees Fahrenheit warmer than it was 100 years ago, surrounded by seas that are on average nine inches higher and being racked by far worse heat waves than the nation experienced only 50 years ago. But those figures offer only the prelude to even more potentially severe impacts. The report suggests that by 2050, the country could see as much as 2.3 additional degrees of warming in the continental United States. By that same year, in a high-end global-warming scenario, coral reefs in Hawaii and the U.S. Pacific territories could be bleaching every single year — conditions in which their survival would be in severe doubt. A record-warm year like 2016 would become routine.

In another major step, the authors of the new report have begun to put dollar signs next to projected climate damage, specifically within the United States. In a worst-case climate-change scenario, the document finds, labor-related losses by the year 2090 as a result of extreme heat — the sort that makes it difficult to work outdoors or seriously lowers productivity — could amount to an estimated $155 billion annually. Deaths from temperature extremes could take an economic toll of $141 billion per year in the same year, while coastal property damage could total $118 billion yearly, researchers found

Of course, mitigating climate change would also mitigate this damage, by as much as 58 percent in the case of high-temperature related deaths, the report finds.

The categorical tone of the new assessments reflects scientists' growing confidence in the ability to detect the role of a changing climate in individual extreme events, such as heat waves and droughts. At the same time, increasingly sophisticated computer simulations now allow them to project future changes in highly specific regions of the country

The Second State of the Carbon Cycle Report, which examines all of North America (not just the United States), finds that over a decade, greenhouse-gas emissions from fossil fuels declined by 1 percent per year. The result is that while North America emitted 24 percent of the world’s emissions in 2004, that was down to 17 percent in 2013. This occurred in part thanks to improvements in vehicle fuel efficiency, the growth of renewable energy and the swapping of coal-burning for natural gas.

“For the globe, we’re still going up, but regionally, there have been these changes in how humans have been acting that have caused our emissions to go down,” said Ted Schuur, a Northern Arizona University expert on permafrost carbon

The report concludes that it appears possible to for economies to grow — at least in the United States, Mexico and Canada — without increasing overall emissions of greenhouse gases. That would be an important signal for the ability of the world to slow climate change over the course of the century

The report also condemns Donald Trump for “actively silencing” climate science, and criticises the Brazilian president, Jair Bolsonaro, for promising to open up the Amazon rainforest to mining

Alston said there were also some positive developments, including legal cases against states and fossil fuel companies, the activism of Greta Thunberg and the worldwide school strikes, and Extinction Rebellion.

“The risk of community discontent, of growing inequality, and of even greater levels of deprivation among some groups, will likely stimulate nationalist, xenophobic, racist and other responses.

Developing countries will bear an estimated 75% of the costs of the climate crisis, the report said, despite the poorest half of the world’s population causing just 10% of carbon dioxide emissions.

t said the greatest impact of the climate crisis would be on those living in poverty, with many losing access to adequate food and water.

aintaining a balanced approach to civil and political rights will be extremely complex.”

The impacts of the climate crisis could increase divisions, Alston said. “We risk a ‘climate apartheid’ scenario where the wealthy pay to escape overheating, hunger, and conflict while the rest of the world is left to suffer,

He said the most recent HRC resolution on the climate crisis did not recognise “that the enjoyment of all human rights by vast numbers of people is gravely threatened” or “the need for the deep social and economic transformation, which almost all observers agree is urgent if climate catastrophe is to be averted”.

nternational climate treaties have been ineffective, the report said, with even the 2015 Paris accord still leaving the world on course for a catastrophic 3C (equivalent to an increase of 5.4F) of heating without further action

“States have marched past every scientific warning and threshold, and what was once considered catastrophic warming now seems like a best-case scenario,” the report said.

he US president is one of the few individuals named in the report. “He has placed former lobbyists in oversight roles, adopted industry talking points, presided over an aggressive rollback of environmental regulations, and is actively silencing and obfuscating climate science.”

A state that fails to take any feasible steps to reduce greenhouse gas emissions is violating their human rights obligations.”

Moody’s Investors Service, a major credit ratings agency, has already said that it wants to take climate into account when weighing the financial health of companies and municipalities.

t says that “water- and vector-borne diseases such as malaria and dengue fever will likely be the largest direct effect of changes in human health and the associated productivity loss.”

The hardest-hit economies will be some of the fastest-growing ones — Brazil, Russia, India, China and South Africa, the report says.

report also forecasts lower oil and natural gas demand, dealing a blow to oil-exporting countries, especially in the Middle East. It forecasts that Saudi GDP will drop more than 10 percent by 2048; the kingdom would be the country harmed the most by climate change, hurting government revenue

Of the 12 largest economies, India will be the worst hit, the report says, with GDP growing 2.5 percentage points more slowly than it would without the effects of climate change

The country’s service industry will be hit by heat stress, agricultural productivity will fall, and health-care costs will climb

the scenarios only go through 2048. The Moody’s report says “the distress compounds over time and is far more severe in the second half of the century.”

He added: “Most of the models go out 30 years, but, really, the damage to the economy is in the next half-century, and we haven’t developed the tools to look out that far.”

That’s why it is so hard to get people focused on this issue and get a comprehensive policy response,” Zandi said. “Business is focused on the next year, or five years out.”

Chubb, one of the biggest insurance firms in the United States, on Monday said it would no longer sell insurance to new coal-fired power plants or sell new policies to companies that derive more than 30 percent of their revenue from the mining of coal used in power plants.

Hammond said that the company still needs to stop insuring new coal mines and the oil sands, or tar sands, in northern Alberta.

“new coal projects cannot be built without insurance, and Chubb just dealt a blow to the dozens of companies that are still betting on the expansion of coal globally.”

the chief economist of Equinor, the Norwegian oil company previously known as Statoil, has written a report that looks at three scenarios for climate change and its impact on global economies, especially on energy. Only one of those, the report said, would lead to a sustainable path, but that path comes with enormous challenges. To reach that set of targets by 2050, “almost all use of coal must be eradicated

oil demand would need to be halved, and natural gas demand trimmed by more than 10 percent.

more than half of new cars would have to be electric vehicles by 2030

Electricity demand will double, yet wind and solar would equal the entire current electricity output, a leap from current levels

Waerness also said that the company currently assumes a carbon price of $55 a ton when considering whether to finance new energy projects

The study, in other words, isn’t about how much see level rise happens this century, but whether this century’s emissions bank enough carbon for total ice melt down—or some less drastic version. “Our analysis really looks at a 2000 year envelope,” says Strauss.

Under the ice, Greenland and Antarctica are uncharted territories. In order to calculate the rate at which those massive ice sheets slough off, Levermann says he would need to know more about the texture of the underlying rock.

there is no sign of flying long-haul on an electric plane any time soon.

The answer to this is to remove carbon dioxide from the atmosphere, using “negative emissions technologies”

How can it be done? The UK is betting on bioenergy with carbon capture and storage, BECCS, where carbon is removed from the atmosphere by crops or trees as they grow. This biomass is then burned in a power station to generate electricity, and the waste carbon dioxide is pumped far underground

A second approach is to restore or enhance processes that naturally remove carbon dioxide from the atmospher

orest restoration removes carbon by storing it in trees, and soils can also take up carbon, for example, if crushed silicate rocks are spread on to them, enhancing a natural chemical process

Politicians and their advisers love them, because they can announce a target such as 1.5C while planning to exceed it, with temperatures hopefully clawed back later in the century through negative emissions.

The greater the negative emissions, the less decarbonisation is needed. Negative emissions technologies are deployed as a weapon to avoid taking serious action on climate.

Most scenarios have more than 730bn tonnes of carbon dioxide sequestered as negative emissions this century. That is equivalent to all the carbon dioxide emitted since the industrial revolution by the US, the UK, Germany and China combined. There just isn’t enough land to suck up that much carbon into new forests

using BECCS to remove this much carbon, as most scenarios assume, would require an area of new cropland larger than India, plus building a facility to store 1m tonnes of carbon a year every single day from 2025 until 2050. Negative emissions at this scale are the stuff of fantasy.

Extreme floods that have historically struck some coastal cities and small island nations once every 100 years will become an annual occurrence by 2050

if emissions continue to increase, global sea levels could rise by more than three feet by the end of this century — around 12 percent higher than the group estimated as recently as 2013

Melting glaciers could harm water supplies, and warming oceans could wreck marine fisheries.

“The conclusion is inescapable: The impacts of climate change on the ocean are well underway. Unless we take very serious action very soon, these impacts will get worse — much, much worse.”

More than 100 scientists from around the world contributed to the latest report by the IPCC, which found that profound and potentially devastating consequences lie ahead for marine life, Arctic ecosystems and entire human societies if climate change continues unabated.

While dozens of smaller nations did unveil plans for coming years, the world’s largest emitters have stopped short of committing to transformational changes.

Sea level rise is accelerating, and the world could see 3.6 feet in total sea level rise by the year 2100 in a very high-emissions scenario. In 2013, t

The ocean is losing oxygen, growing more acidic, taking up an increasing amount of heat, and becoming more stratified, with warm water at the surface preventing cooler, nutrient rich waters from rising. All of these changes have profound consequences for marine ecosystems.

when scientists behind the report looked at an alternative method for gauging how much seas could rise — simply canvassing the views of experts — even larger estimates emerged. The group’s findings only highlight “likely” amounts of sea level rise, meaning they do not represent worst-case scenarios.

For some major coastal cities, a historical 100-year flood event will happen annually by the year 2050. That includes large cities such as Jakarta, Manila, Bangkok, Lima, Singapore, Barcelona and Sydney, the report says

In the United States, cities facing fast-moving sea-level danger include Los Angeles, Miami, Savannah, Honolulu, San Juan, Key West and San Diego.

“The world’s coasts provide a home to around 1.9 billion people and over half of the world’s megacities — all of which are in grave danger if we don’t act immediately to prevent rising temperatures and sea levels,”

“Extreme high temperatures, coastal flooding, and more frequent natural disasters are becoming the new normal. ... This is what the climate crisis looks like now.

the system could still tip toward very large ice losses from Greenland and Antarctica. If that happens, the rate of sea-level rise could become truly catastrophic, especially by the years 2200 and 2300, when it could exceed 10 feet.

Permafrost, which contains enormous amounts of carbon that can be released as it thaws, has warmed to “record high levels.” Summer Arctic sea ice extent is now probably lower than at any time in “at least 1,000 years,” and the oldest, thickest ice has already declined by 90 percent.

“Over the 21st century, the ocean is projected to transition to unprecedented conditions,”

“Even our language has to adapt: What once was called ‘climate change’ is now truly a ‘climate crisis.’ … We are seeing unprecedented temperatures, unrelenting storms and undeniable science.”

One of the most shocking findings involves “marine heat waves,” which have been blamed for mass deaths of corals, kelp forests and other key ocean organisms. The large majority of these events are already directly attributable to climate change, and by the year 2100, they will become 20 times more common in the best case, and 50 times as common in the absolute worst case, compared with the late 1800s

Many of these changes to oceans and ice are unfolding in parts of the Earth where few people live, and so the shifts are not always readily visible to most humans. But the changes taking place there ultimately will affect people around the globe, in the form of rising seas and other impacts. And as those impacts worsen, so does the difficulty of adapting to them.

the grim findings in Wednesday’s report should be a call to action.

"We must not let these climate change impacts paralyze us,” she said in an email. “We must address root causes of climate change by slowing and eventually stopping accumulation of greenhouse gas emissions.”

There is much that humans can do to blunt the expected impacts in the meantime, she said, such as restoring mangroves and protecting reefs and marshes to reduce storm impacts on coastal communities.

“Alone, these measures cannot meet all the challenges of climate change to oceans and coasts, but they are doable, cost-effective and make a difference,”

All vaccines work according to the same basic principle. They present part or all of the pathogen to the human immune system, usually in the form of an injection and at a low dose, to prompt the system to produce antibodies to the pathogen. Antibodies are a kind of immune memory which, having been elicited once, can be quickly mobilised again if the person is exposed to the virus in its natural form.

Cepi’s original portfolio of four funded Covid-19 vaccine projects was heavily skewed towards these more innovative technologies, and last week it announced $4.4m (£3.4m) of partnership funding with Novavax and with a University of Oxford vectored vaccine project. “Our experience with vaccine development is that you can’t anticipate where you’re going to stumble,” says Hatchett, meaning that diversity is key. And the stage where any approach is most likely to stumble is clinical or human trials, which, for some of the candidates, are about to get under way.

An illustration of that is a vaccine that was produced in the 1960s against respiratory syncytial virus, a common virus that causes cold-like symptoms in children. In clinical trials, this vaccine was found to aggravate those symptoms in infants who went on to catch the virus. A similar effect was observed in animals given an early experimental Sars vaccine. It was later modified to eliminate that problem but, now that it has been repurposed for Sars-CoV-2, it will need to be put through especially stringent safety testing to rule out the risk of enhanced disease.

Once a Covid-19 vaccine has been approved, a further set of challenges will present itself. “Getting a vaccine that’s proven to be safe and effective in humans takes one at best about a third of the way to what’s needed for a global immunisation programme,” says global health expert Jonathan Quick of Duke University in North Carolina, author of The End of Epidemics (2018). “Virus biology and vaccines technology could be the limiting factors, but politics and economics are far more likely to be the barrier to immunisation.”

Because pandemics tend to hit hardest those countries that have the most fragile and underfunded healthcare systems, there is an inherent imbalance between need and purchasing power when it comes to vaccines. During the 2009 H1N1 flu pandemic, for example, vaccine supplies were snapped up by nations that could afford them, leaving poorer ones short. But you could also imagine a scenario where, say, India – a major supplier of vaccines to the developing world – not unreasonably decides to use its vaccine production to protect its own 1.3 billion-strong population first, before exporting any.

• This article was amended on 19 March 2020. An earlier version incorrectly stated that the Sabin Vaccine Institute was collaborating with the Coalition for Epidemic Preparedness Innovations (Cepi) on a Covid-19 vaccine.

The 2019 study warned otherwise — specifically urging Americans not to conflate the risks of a typical flu and a pandemic.

The existence of that warning undermines administration officials’ contentions in recent weeks that no one could have seen the virus damaging the economy as it has.

One of the authors of the study, who has since left the White House, now says it would make sense for the administration to effectively shut down most economic activity for two to eight months to slow the virus.

Government officials estimated Tuesday that the deadly pathogen could kill between 100,000 and 240,000 Americans.

it is unclear how the White House is tallying the potential benefits and costs — in dollar figures and human lives — of competing timetables for action.

The director of the National Economic Council, Larry Kudlow, told ABC News on Sunday that “it could be four weeks, it could be eight weeks” before economic activity resumes. “I say that hopefully,”

seeks to determine the optimal length of a national suppression of economic activity,

It assigned a value of $12.3 million per life for Americans between the ages of 18 and 49, compared with $5.3 million for those 65 and over.

In a best-case scenario, Ms. Scherbina concludes, a national suppression of economic activity to flatten the infection curve must last at least seven weeks.

In a worst case, where the shutdown proves less effective at slowing the rate of new infections, it would be economically optimal to keep the economy shuttered for nearly eight months.

Suppression efforts inflict considerable damage on the economy, reducing activity by about $36 billion per week, the study estimates. Ms. Scherbina said the optimal durations would remain largely unchanged even if the weekly damage was twice that high.

But the efforts would save nearly two million lives when compared with a scenario in which the government did nothing to suppress the economy and the spread of the virus

doing nothing would impose a $13 trillion cost to the economy — equal to about two-thirds of the amount of economic activity that the United States was projected to generate this year

Ms. Scherbina based her estimates on the models she built when she was a senior economist at the Council of Economic Advisers and the lead author of the September paper, “Mitigating the Impact of Pandemic Influenza Through Vaccine Innovation,

The 2019 White House study called for new federal efforts to speed up the time it takes to develop and deploy new vaccines

At even the highest rates it modeled, the pandemic flu in the exercise was still less contagious and less deadly than epidemiologists now say the coronavirus could be in the United States

“I don’t think corona is as big a threat as people make it out to be,” the acting chairman of the Council of Economic Advisers, Tomas Philipson, told reporters during a Feb. 18 briefing, on the same day that more than a dozen American cruise ship passengers who had contracted the virus were evacuated home

Mr. Philipson, whose academic specialty is health economics, was the acting head of the council when the September report was published

To contain such a pathogen, nations must develop a test and use it to identify infected people, isolate them, and trace those they’ve had contact with. That is what South Korea, Singapore, and Hong Kong did to tremendous effect. It is what the United States did not.

That a biomedical powerhouse like the U.S. should so thoroughly fail to create a very simple diagnostic test was, quite literally, unimaginable. “I’m not aware of any simulations that I or others have run where we [considered] a failure of testing,”

The testing fiasco was the original sin of America’s pandemic failure, the single flaw that undermined every other countermeasure. If the country could have accurately tracked the spread of the virus, hospitals could have executed their pandemic plans, girding themselves by allocating treatment rooms, ordering extra supplies, tagging in personnel, or assigning specific facilities to deal with COVID-19 cases.

None of that happened. Instead, a health-care system that already runs close to full capacity, and that was already challenged by a severe flu season, was suddenly faced with a virus that had been left to spread, untracked, through communities around the country.

With little room to surge during a crisis, America’s health-care system operates on the assumption that unaffected states can help beleaguered ones in an emergency.

That ethic works for localized disasters such as hurricanes or wildfires, but not for a pandemic that is now in all 50 states. Cooperation has given way to competition

Partly, that’s because the White House is a ghost town of scientific expertise. A pandemic-preparedness office that was part of the National Security Council was dissolved in 2018. On January 28, Luciana Borio, who was part of that team, urged the government to “act now to prevent an American epidemic,” and specifically to work with the private sector to develop fast, easy diagnostic tests. But with the office shuttered, those warnings were published in The Wall Street Journal, rather than spoken into the president’s ear.

Rudderless, blindsided, lethargic, and uncoordinated, America has mishandled the COVID-19 crisis to a substantially worse degree than what every health expert I’ve spoken with had feared. “Much worse,”

“Beyond any expectations we had,” said Lauren Sauer, who works on disaster preparedness at Johns Hopkins Medicine. “As an American, I’m horrified,” said Seth Berkley, who heads Gavi, the Vaccine Alliance. “The U.S. may end up with the worst outbreak in the industrialized world.”

it will be difficult—but not impossible—for the United States to catch up. To an extent, the near-term future is set because COVID-19 is a slow and long illness. People who were infected several days ago will only start showing symptoms now, even if they isolated themselves in the meantime. Some of those people will enter intensive-care units in early April

A “massive logistics and supply-chain operation [is] now needed across the country,” says Thomas Inglesby of Johns Hopkins Bloomberg School of Public Health. That can’t be managed by small and inexperienced teams scattered throughout the White House. The solution, he says, is to tag in the Defense Logistics Agency—a 26,000-person group that prepares the U.S. military for overseas operations and that has assisted in past public-health crises, including the 2014 Ebola outbreak.

The first and most important is to rapidly produce masks, gloves, and other personal protective equipment

it would also come at a terrible cost: SARS-CoV-2 is more transmissible and fatal than the flu, and it would likely leave behind many millions of corpses and a trail of devastated health systems.

This agency can also coordinate the second pressing need: a massive rollout of COVID-19 tests.

These measures will take time, during which the pandemic will either accelerate beyond the capacity of the health system or slow to containable levels. Its course—and the nation’s fate—now depends on the third need, which is social distancing.

There are now only two groups of Americans. Group A includes everyone involved in the medical response, whether that’s treating patients, running tests, or manufacturing supplies. Group B includes everyone else, and their job is to buy Group A more time. Group B must now “flatten the curve” by physically isolating themselves from other people to cut off chains of transmission.

Given the slow fuse of COVID-19, to forestall the future collapse of the health-care system, these seemingly drastic steps must be taken immediately, before they feel proportionate, and they must continue for several weeks.

Persuading a country to voluntarily stay at home is not easy, and without clear guidelines from the White House, mayors, governors, and business owners have been forced to take their own steps.

when the good of all hinges on the sacrifices of many, clear coordination matters—the fourth urgent need

Pundits and business leaders have used similar rhetoric, arguing that high-risk people, such as the elderly, could be protected while lower-risk people are allowed to go back to work. Such thinking is seductive, but flawed. It overestimates our ability to assess a person’s risk, and to somehow wall off the ‘high-risk’ people from the rest of society. It underestimates how badly the virus can hit ‘low-risk’ groups, and how thoroughly hospitals will be overwhelmed if even just younger demographics are falling sick.

A recent analysis from the University of Pennsylvania estimated that even if social-distancing measures can reduce infection rates by 95 percent, 960,000 Americans will still need intensive care.

There are only about 180,000 ventilators in the U.S. and, more pertinently, only enough respiratory therapists and critical-care staff to safely look after 100,000 ventilated patients. Abandoning social distancing would be foolish. Abandoning it now, when tests and protective equipment are still scarce, would be catastrophic.

If Trump stays the course, if Americans adhere to social distancing, if testing can be rolled out, and if enough masks can be produced, there is a chance that the country can still avert the worst predictions about COVID-19, and at least temporarily bring the pandemic under control. No one knows how long that will take, but it won’t be quick. “It could be anywhere from four to six weeks to up to three months,” Fauci said, “but I don’t have great confidence in that range.”

there are three possible endgames: one that’s very unlikely, one that’s very dangerous, and one that’s very long.

The first is that every nation manages to simultaneously bring the virus to heel, as with the original SARS in 2003. Given how widespread the coronavirus pandemic is, and how badly many countries are faring, the odds of worldwide synchronous control seem vanishingly small.

The second is that the virus does what past flu pandemics have done: It burns through the world and leaves behind enough immune survivors that it eventually struggles to find viable hosts. This “herd immunity” scenario would be quick, and thus tempting

The U.S. has fewer hospital beds per capita than Italy. A study released by a team at Imperial College London concluded that if the pandemic is left unchecked, those beds will all be full by late April. By the end of June, for every available critical-care bed, there will be roughly 15 COVID-19 patients in need of one.  By the end of the summer, the pandemic will have directly killed 2.2 million Americans,

The third scenario is that the world plays a protracted game of whack-a-mole with the virus, stamping out outbreaks here and there until a vaccine can be produced. This is the best option, but also the longest and most complicated.

there are no existing vaccines for coronaviruses—until now, these viruses seemed to cause diseases that were mild or rare—so researchers must start from scratch.

The first steps have been impressively quick. Last Monday, a possible vaccine created by Moderna and the National Institutes of Health went into early clinical testing. That marks a 63-day gap between scientists sequencing the virus’s genes for the first time and doctors injecting a vaccine candidate into a person’s arm. “It’s overwhelmingly the world record,” Fauci said.

The initial trial will simply tell researchers if the vaccine seems safe, and if it can actually mobilize the immune system. Researchers will then need to check that it actually prevents infection from SARS-CoV-2. They’ll need to do animal tests and large-scale trials to ensure that the vaccine doesn’t cause severe side effects. They’ll need to work out what dose is required, how many shots people need, if the vaccine works in elderly people, and if it requires other chemicals to boost its effectiveness.

No matter which strategy is faster, Berkley and others estimate that it will take 12 to 18 months to develop a proven vaccine, and then longer still to make it, ship it, and inject it into people’s arms.

as the status quo returns, so too will the virus. This doesn’t mean that society must be on continuous lockdown until 2022. But “we need to be prepared to do multiple periods of social distancing,” says Stephen Kissler of Harvard.

First: seasonality. Coronaviruses tend to be winter infections that wane or disappear in the summer. That may also be true for SARS-CoV-2, but seasonal variations might not sufficiently slow the virus when it has so many immunologically naive hosts to infect.

Second: duration of immunity. When people are infected by the milder human coronaviruses that cause cold-like symptoms, they remain immune for less than a year. By contrast, the few who were infected by the original SARS virus, which was far more severe, stayed immune for much longer.

scientists will need to develop accurate serological tests, which look for the antibodies that confer immunity. They’ll also need to confirm that such antibodies actually stop people from catching or spreading the virus. If so, immune citizens can return to work, care for the vulnerable, and anchor the economy during bouts of social distancing.

Aspects of America’s identity may need rethinking after COVID-19. Many of the country’s values have seemed to work against it during the pandemic. Its individualism, exceptionalism, and tendency to equate doing whatever you want with an act of resistance meant that when it came time to save lives and stay indoors, some people flocked to bars and clubs.

“We can keep schools and businesses open as much as possible, closing them quickly when suppression fails, then opening them back up again once the infected are identified and isolated. Instead of playing defense, we could play more offense.”

The vaccine may need to be updated as the virus changes, and people may need to get revaccinated on a regular basis, as they currently do for the flu. Models suggest that the virus might simmer around the world, triggering epidemics every few years or so. “But my hope and expectation is that the severity would decline, and there would be less societal upheaval,”

After infections begin ebbing, a secondary pandemic of mental-health problems will follow.

But “there is also the potential for a much better world after we get through this trauma,”

Testing kits can be widely distributed to catch the virus’s return as quickly as possible. There’s no reason that the U.S. should let SARS-CoV-2 catch it unawares again, and thus no reason that social-distancing measures need to be deployed as broadly and heavy-handedly as they now must be.

Pandemics can also catalyze social change. People, businesses, and institutions have been remarkably quick to adopt or call for practices that they might once have dragged their heels on, including working from home, conference-calling to accommodate people with disabilities, proper sick leave, and flexible child-care arrangements.

Perhaps the nation will learn that preparedness isn’t just about masks, vaccines, and tests, but also about fair labor policies and a stable and equal health-care system. Perhaps it will appreciate that health-care workers and public-health specialists compose America’s social immune system, and that this system has been suppressed.

Attitudes to health may also change for the better. The rise of HIV and AIDS “completely changed sexual behavior among young people who were coming into sexual maturity at the height of the epidemic,”

Years of isolationist rhetoric had consequences too.

“People believed the rhetoric that containment would work,” says Wendy Parmet, who studies law and public health at Northeastern University. “We keep them out, and we’ll be okay. When you have a body politic that buys into these ideas of isolationism and ethnonationalism, you’re especially vulnerable when a pandemic hits.”

Pandemics are democratizing experiences. People whose privilege and power would normally shield them from a crisis are facing quarantines, testing positive, and losing loved ones. Senators are falling sick. The consequences of defunding public-health agencies, losing expertise, and stretching hospitals are no longer manifesting as angry opinion pieces, but as faltering lungs.

After COVID-19, attention may shift to public health. Expect to see a spike in funding for virology and vaccinology, a surge in students applying to public-health programs, and more domestic production of medical supplies.

The lessons that America draws from this experience are hard to predict, especially at a time when online algorithms and partisan broadcasters only serve news that aligns with their audience’s preconceptions.

“The transitions after World War II or 9/11 were not about a bunch of new ideas,” he says. “The ideas are out there, but the debates will be more acute over the next few months because of the fluidity of the moment and willingness of the American public to accept big, massive changes.”

One could easily conceive of a world in which most of the nation believes that America defeated COVID-19. Despite his many lapses, Trump’s approval rating has surged. Imagine that he succeeds in diverting blame for the crisis to China, casting it as the villain and America as the resilient hero.

One could also envisage a future in which America learns a different lesson. A communal spirit, ironically born through social distancing, causes people to turn outward, to neighbors both foreign and domestic. The election of November 2020 becomes a repudiation of “America first” politics. The nation pivots, as it did after World War II, from isolationism to international cooperation

The U.S. leads a new global partnership focused on solving challenges like pandemics and climate change.

In 2030, SARS-CoV-3 emerges from nowhere, and is brought to heel within a month.

On the Global Health Security Index, a report card that grades every country on its pandemic preparedness, the United States has a score of 83.5—the world’s highest. Rich, strong, developed, America is supposed to be the readiest of nations. That illusion has been shattered. Despite months of advance warning as the virus spread in other countries, when America was finally tested by COVID-19, it failed.

They worried that a vaccine would initially elude scientists, that weary citizens would abandon restrictions despite the risks, that the virus would be with us from now on.

Most experts believed that once the crisis was over, the nation and its economy would revive quickly. But there would be no escaping a period of intense pain.

Exactly how the pandemic will end depends in part on medical advances still to come. It will also depend on how individual Americans behave in the interim. If we scrupulously protect ourselves and our loved ones, more of us will live. If we underestimate the virus, it will find us.

More Americans may die than the White House admits.

The epidemiological model often cited by the White House, which was produced by the University of Washington’s Institute for Health Metrics and Evaluation, originally predicted 100,000 to 240,000 deaths by midsummer. Now that figure is 60,000.

The institute’s projection runs through Aug. 4, describing only the first wave of this epidemic. Without a vaccine, the virus is expected to circulate for years, and the death tally will rise over time.

Fatality rates depend heavily on how overwhelmed hospitals get and what percentage of cases are tested. China’s estimated death rate was 17 percent in the first week of January, when Wuhan was in chaos, according to a Center for Evidence-Based Medicine report, but only 0.7 percent by late February.

Various experts consulted by the Centers for Disease Control and Prevention in March predicted that the virus eventually could reach 48 percent to 65 percent of all Americans, with a fatality rate just under 1 percent, and would kill up to 1.7 million of them if nothing were done to stop the spread.

A model by researchers at Imperial College London cited by the president on March 30 predicted 2.2 million deaths in the United States by September under the same circumstances.

China has officially reported about 83,000 cases and 4,632 deaths, which is a fatality rate of over 5 percent. The Trump administration has questioned the figures but has not produced more accurate ones.

The tighter the restrictions, experts say, the fewer the deaths and the longer the periods between lockdowns. Most models assume states will eventually do widespread temperature checks, rapid testing and contact tracing, as is routine in Asia.

In this country, hospitals in several cities, including New York, came to the brink of chaos.

Only when tens of thousands of antibody tests are done will we know how many silent carriers there may be in the United States. The C.D.C. has suggested it might be 25 percent of those who test positive. Researchers in Iceland said it might be double that.

China is also revising its own estimates. In February, a major study concluded that only 1 percent of cases in Wuhan were asymptomatic. New research says perhaps 60 percent were.

The virus may also be mutating to cause fewer symptoms. In the movies, viruses become more deadly. In reality, they usually become less so, because asymptomatic strains reach more hosts. Even the 1918 Spanish flu virus eventually faded into the seasonal H1N1 flu.

The lockdowns will end, but haltingly.

it is likely a safe bet that at least 300 million of us are still vulnerable.

Until a vaccine or another protective measure emerges, there is no scenario, epidemiologists agreed, in which it is safe for that many people to suddenly come out of hiding. If Americans pour back out in force, all will appear quiet for perhaps three weeks.

The gains to date were achieved only by shutting down the country, a situation that cannot continue indefinitely. The White House’s “phased” plan for reopening will surely raise the death toll no matter how carefully it is executed.

Every epidemiological model envisions something like the dance

On the models, the curves of rising and falling deaths resemble a row of shark teeth.

Surges are inevitable, the models predict, even when stadiums, churches, theaters, bars and restaurants remain closed, all travelers from abroad are quarantined for 14 days, and domestic travel is tightly restricted to prevent high-intensity areas from reinfecting low-intensity ones.

In his wildly popular March 19 article in Medium, “Coronavirus: The Hammer and the Dance,” Tomas Pueyo correctly predicted the national lockdown, which he called the hammer, and said it would lead to a new phase, which he called the dance, in which essential parts of the economy could reopen, including some schools and some factories with skeleton crews.

Even the “Opening Up America Again” guidelines Mr. Trump issued on Thursday have three levels of social distancing, and recommend that vulnerable Americans stay hidden. The plan endorses testing, isolation and contact tracing — but does not specify how these measures will be paid for, or how long it will take to put them in place.

On Friday, none of that stopped the president from contradicting his own message by sending out tweets encouraging protesters in Michigan, Minnesota and Virginia to fight their states’ shutdowns.

China did not allow Wuhan, Nanjing or other cities to reopen until intensive surveillance found zero new cases for 14 straight days, the virus’s incubation period.

Compared with China or Italy, the United States is still a playground.Americans can take domestic flights, drive where they want, and roam streets and parks. Despite restrictions, everyone seems to know someone discreetly arranging play dates for children, holding backyard barbecues or meeting people on dating apps.

Even with rigorous measures, Asian countries have had trouble keeping the virus under control

But if too many people get infected at once, new lockdowns will become inevitable. To avoid that, widespread testing will be imperative.

Reopening requires declining cases for 14 days, the tracing of 90 percent of contacts, an end to health care worker infections, recuperation places for mild cases and many other hard-to-reach goals.

Immunity will become a societal advantage.

Imagine an America divided into two classes: those who have recovered from infection with the coronavirus and presumably have some immunity to it; and those who are still vulnerable.

“It will be a frightening schism,” Dr. David Nabarro, a World Health Organization special envoy on Covid-19, predicted. “Those with antibodies will be able to travel and work, and the rest will be discriminated against.”

Soon the government will have to invent a way to certify who is truly immune. A test for IgG antibodies, which are produced once immunity is established, would make sense

Dr. Fauci has said the White House was discussing certificates like those proposed in Germany. China uses cellphone QR codes linked to the owner’s personal details so others cannot borrow them.

As Americans stuck in lockdown see their immune neighbors resuming their lives and perhaps even taking the jobs they lost, it is not hard to imagine the enormous temptation to join them through self-infection

My daughter, who is a Harvard economist, keeps telling me her age group needs to have Covid-19 parties to develop immunity and keep the economy going,”

It would be a gamble for American youth, too. The obese and immunocompromised are clearly at risk, but even slim, healthy young Americans have died of Covid-19.

The virus can be kept in check, but only with expanded resources.

Resolve to Save Lives, a public health advocacy group run by Dr. Thomas R. Frieden, the former director of the C.D.C., has published detailed and strict criteria for when the economy can reopen and when it must be closed.

once a national baseline of hundreds of thousands of daily tests is established across the nation, any viral spread can be spotted when the percentage of positive results rises.

To keep the virus in check, several experts insisted, the country also must start isolating all the ill — including mild cases.

“If I was forced to select only one intervention, it would be the rapid isolation of all cases,”

In China, anyone testing positive, no matter how mild their symptoms, was required to immediately enter an infirmary-style hospital — often set up in a gymnasium or community center outfitted with oxygen tanks and CT scanners.

There, they recuperated under the eyes of nurses. That reduced the risk to families, and being with other victims relieved some patients’ fears.

Still, experts were divided on the idea of such wards

Ultimately, suppressing a virus requires testing all the contacts of every known case. But the United States is far short of that goal.

In China’s Sichuan Province, for example, each known case had an average of 45 contacts.

The C.D.C. has about 600 contact tracers and, until recently, state and local health departments employed about 1,600, mostly for tracing syphilis and tuberculosis cases.

China hired and trained 9,000 in Wuhan alone. Dr. Frieden recently estimated that the United States will need at least 300,000.

There will not be a vaccine soon.

any effort to make a vaccine will take at least a year to 18 months.

the record is four years, for the mumps vaccine.

for unclear reasons, some previous vaccine candidates against coronaviruses like SARS have triggered “antibody-dependent enhancement,” which makes recipients more susceptible to infection, rather than less. In the past, vaccines against H.I.V. and dengue have unexpectedly done the same.

A new vaccine is usually first tested in fewer than 100 young, healthy volunteers. If it appears safe and produces antibodies, thousands more volunteers — in this case, probably front-line workers at the highest risk — will get either it or a placebo in what is called a Phase 3 trial.

It is possible to speed up that process with “challenge trials.” Scientists vaccinate small numbers of volunteers, wait until they develop antibodies, and then “challenge” them with a deliberate infection to see if the vaccine protects them.

Normally, it is ethically unthinkable to challenge subjects with a disease with no cure, such as Covid-19.

“Fewer get harmed if you do a challenge trial in a few people than if you do a Phase 3 trial in thousands,” said Dr. Lipsitch, who recently published a paper advocating challenge trials in the Journal of Infectious Diseases. Almost immediately, he said, he heard from volunteers.

The hidden danger of challenge trials, vaccinologists explained, is that they recruit too few volunteers to show whether a vaccine creates enhancement, since it may be a rare but dangerous problem.

if a vaccine is invented, the United States could need 300 million doses — or 600 million if two shots are required. And just as many syringes.

“People have to start thinking big,” Dr. Douglas said. “With that volume, you’ve got to start cranking it out pretty soon.”

Treatments are likely to arrive first.

The modern alternative is monoclonal antibodies. These treatment regimens, which recently came very close to conquering the Ebola epidemic in eastern Congo, are the most likely short-term game changer, experts said.

as with vaccines, growing and purifying monoclonal antibodies takes time. In theory, with enough production, they could be used not just to save lives but to protect front-line workers.

Having a daily preventive pill would be an even better solution, because pills can be synthesized in factories far faster than vaccines or antibodies can be grown and purified.

Goodbye, ‘America First.’

A public health crisis of this magnitude requires international cooperation on a scale not seen in decades. Yet Mr. Trump is moving to defund the W.H.O., the only organization capable of coordinating such a response.

And he spent most of this year antagonizing China, which now has the world’s most powerful functioning economy and may become the dominant supplier of drugs and vaccines. China has used the pandemic to extend its global influence, and says it has sent medical gear and equipment to nearly 120 countries.

This is not a world in which “America First” is a viable strategy, several experts noted.

“If President Trump cares about stepping up the public health efforts here, he should look for avenues to collaborate with China and stop the insults,”

If we alienate the Chinese with our rhetoric, I think it will come back to bite us,” he said.“What if they come up with the first vaccine? They have a choice about who they sell it to. Are we top of the list? Why would we be?”

Once the pandemic has passed, the national recovery may be swift. The economy rebounded after both world wars, Dr. Mulder noted.

In one of the most provocative analyses in his follow-up article, “Coronavirus: Out of Many, One,” Mr. Pueyo analyzed Medicare and census data on age and obesity in states that recently resisted shutdowns and counties that voted Republican in 2016.

He calculated that those voters could be 30 percent more likely to die of the virus.

In the periods after both wars, Dr. Mulder noted, society and incomes became more equal. Funds created for veterans’ and widows’ pensions led to social safety nets, measures like the G.I. Bill and V.A. home loans were adopted, unions grew stronger, and tax benefits for the wealthy withered.

If a vaccine saves lives, many Americans may become less suspicious of conventional medicine and more accepting of science in general — including climate change

Lapan added that it is important for the president to address the public about a topic as serious as the pandemic but said Trump should quickly “turn it over to the experts and leave, and not turn it into this stream of consciousness of every topic he wants to talk about and the adoration that seems to be required from everybody else who participates.”

“Trump is a sales guy, and it’s all about point of sale,” said Stuart Stevens, a longtime Republican operative and frequent Trump critic. “It’s not about repeat customers and follow-ups. He wants to get the sale — that’s it — he wants to sell you the undercoating for your car, and it’s not his problem if the car breaks driving off of the lot.”

Trump’s mind at times was elsewhere. A few hours before his news conference, he took to Twitter to brag about the high television ratings of his coronavirus updates, noting that they were on par with the season finale of “The Bachelor,” an ABC reality hit.

At day’s end, when Trump strode into the White House press briefing room to deliver a coronavirus update, he turned over the presidential lectern to an array of business executives, who alternately praised him and pitched their products.

The potpourri quality of Trump’s message to a nation in crisis that day was a stark contrast to Franklin D. Roosevelt, who as president during the Great Depression and World War II offered his reassurances in a series of fireside chats broadcast nationally — and he limited them to have maximum impact.

“He only delivered these fireside chats every couple of months, when there was an essential moment for the president to speak,”

“Someone said to him, ‘Why don’t you go on the radio every night? Your speeches are so effective.’ He said, ‘If my speeches become routine they will lose their effectiveness.’ And he said, ‘It takes me three or four days to work on a fireside chat — and I have to run the country, too.”

By Tuesday, Trump had finally come to acknowledge the sheer magnitude of the crisis.

the president and his medical experts offered a somber and grim projection: In a best-case scenario, and with strict abidance by social distancing, between 100,000 and 240,000 Americans would die of the coronavirus.

The worst-case scenario was even more horrifying: Without community mitigation measures, the models presented by the White House predict 1.5 million to 2.2 million Americans could die.

Lockhart said that Tuesday’s news conference was a concerted effort by the administration to “rewrite history,” after two months of Trump playing down the threat of the virus. He added that there appeared to be a political calculation as well: By revealing specific projected fatalities, Trump laid the groundwork to be able to claim victory ahead of November’s election if the death toll is substantially less than predicted.

The Centers for Disease Control and Prevention had developed new guidance to mitigate the coronavirus, recommending all Americans wear face masks, and as with many announcements by the federal government, Trump chose to unveil it himself.

But he risked diluting the effectiveness of the measure — designed to prevent asymptomatic carriers of the virus from spreading to others — by stressing it was voluntary and musing at Friday’s news conference that he wouldn’t be seen wearing a mask himself.

his vanity, it seemed, could not abide wearing a mask.Asked why he opposed covering his nose and mouth as the CDC recommends, Trump struggled to articulate his hesitation.“Somehow sitting in the Oval Office behind that beautiful Resolute Desk — the great Resolute Desk — I think wearing a face mask as I greet presidents, prime ministers, dictators, kings, queens, I don’t know. Somehow, I don’t see it for myself.”

There’s also a national precedent for Mr. Nelson’s hypothetical: America’s response to gun violence and school shootings.

As a country, we seem resigned to preventable firearm deaths. Each year, 36,000 Americans are killed by guns — roughly 100 per day, most from suicide

In every case, the death tolls climb but we fail to act. There are occasional marches and protests but mostly we continue on with our lives.

As with gun violence, the data medical professionals and governments are relying on during the pandemic is piecemeal. And, as with gun violence, we throw up our hands and deem it intractable.

The federal government could have moved swiftly like some in Europe to “freeze” the economy and commit to paying at least part of workers’ salaries if their companies don’t lay them off. Instead, our economic stimulus has been scattershot and underwhelming.

the administration seems to be cheering on the reopening while internally preparing for a substantial increase of loss of lives. An internal document based on modeling by the Federal Emergency Management Agency obtained by The Times projects that the daily death toll will reach about 3,000 on June 1, a 70 percent increase from the May 1 number of about 1,750.

For Dr. Megan Ranney, an emergency physician and Brown University professor who works on gun violence prevention, the dynamics of the lockdown protesters are familiar.

“This group has moved the reopening debate from a conversation about health and science to a conversation about liberty,” Dr. Ranney told me. “They’ve redefined the debate so it’s no longer about weighing risks and benefits and instead it’s this politicized narrative. It’s like taking a nuanced conversation about gun injury and turning it into an argument about gun rights. It shuts the conversation down.”

As in the gun control debate, public opinion, public health and the public good seem poised to lose out to a select set of personal freedoms.

But it’s a child’s two-dimensional view of freedom — one where any suggestion of collective duty and responsibility for others become the chains of tyranny.

This idea of freedom is also an excuse to serve one’s self before others and a shield to hide from responsibility.

In this narrow worldview, freedom has a price, in the form of an “acceptable” number of human lives lost. It’s a price that will be calculated and then set by a select few. The rest of us merely pay it.

There's more bad news: IFS found that growth in average incomes will be close to zero -- once inflation is taken into account -- over the next two years,

Britain voted in June to leave the EU, setting off a period of tremendous economic and political uncertainty. While the pound immediately plummeted, the most dire economic scenarios envisioned by analysts prior to the referendum have failed to materialize. But growth over the next five years is expected to be 2.4% lower than it would have been had Britain remained a member of the EU.

Prime Minister Theresa May is expected to start formal Brexit negotiations with the EU in the coming weeks. The most likely scenario is that Britain will end up leaving Europe's unified trading market and be forced to negotiate new terms of trade with its biggest partners.

BURNS: That’s what I meant by cavalier. It’s just so run-of-the-mill, as if the extinguishing — and, look, you’re in the military, that’s your job. But just the cavalierness of a surrendered prisoner or a captured prisoner or whatever it is, it’s a spy and obviously he’s lost comrades in this. But there’s no justification for that moment in any rational scenario — any humane scenario, is probably the better way to describe it. And so what it becomes is an abhorrent mirror to the possibilities in ourselves.

This episode is called “Things Fall Apart” and it has to do with the William Butler Yeats poem that Robert Kennedy cites in an editorial that he writes that year opposing the war in no uncertain terms in the New York Times. But it’s also about what the title of the next episode is about: the veneer of civilization.

This is how close we are. I always feel that all of these images here are mirrors. They ask us — and I think one of the gifts of filmmaking is that it permits us to order and sequence images to remind us of not what happens but also what we are capable of ourselves.

And look, murder and war, they’re synonymous. But there’s something about that moment, that photograph and that footage, that are the — it’s the heart of darkness of the whole story.

Of course, as I told my friends on Tuesday, even if you are no longer required to wear a mask, you still can choose to wear one. In Hong Kong and Japan, for example, mask-wearing on public transportation and in crowded public spaces has been a norm -- not a requirement -- for years. For people who are immunosuppressed (for whom the vaccines may not be as effective) or otherwise high-risk, it might be a good idea to choose to continue wearing a mask, especially indoors, regardless of the regulations.

In the one-month period between the Iowa caucuses and Super Tuesday, about 40% of the total number of delegates voting in the first round of the Democratic National Convention will have been selected. In comparison, in 2016 only about a quarter of the delegates were distributed during that same period. A few weeks later, by the end of March, nearly 70% of the delegates will have been chosen.

Which brings us to the final element that makes a brokered convention more likely this year than in the past: the rules change that the Democratic party made to how voting will work at the 2020 convention

The 2008 and 2016 DNC conventions weren't "brokered," though, because Democrats since 1984 have allowed a large number of unpledged or uncommitted delegates to attend and vote at the national convention. These so-called "superdelegates" -- and there were more than 700 of them in Philadelphia in 2016 -- are not bound by voting outcomes in any of the states. In fact, this large number of uncommitted superdelegates has made it difficult for Democratic candidates to obtain a majority of committed convention delegates without them.

The influence of the superdelegates over the years has led to cries of unfairness from candidates who were not awarded the nomination. Both Hillary Clinton in 2008 and Bernie Sanders in 2016 could correctly argue that, had the superdelegates offered them support, they could have been the party's nominee.

The result was a change in the convention rules so that, in 2020, superdelegates will not participate in the first round of voting under this scenario. So it is up to Democratic primary and caucus participants to avoid a brokered convention.

A brokered convention in 2020 would set the stage for a repeat of that scenario. Already, Rep. Tulsi Gabbard is saying that she will fight all the way to the convention. If Biden or Warren were to be handed the nomination by the superdelegates, and Gabbard were to win some delegates, might cries of "Bernie or Bust" on the convention floor be joined by "Tulsi or Trump"?

But the Biden campaign on Monday fired back, saying that “under no scenario” could Trump be declared a victor on Election Night, citing historic early voter turnout, and the way in which states count votes.

Republicans, for their part, warn there is a potential for widespread fraud and confusion in November’s election due to the unprecedented scale of mail-in ballots in states across the nation.

It is that like 2016 (although I could bore on for some time about why this is not quite true) the polls are wrong and Donald Trump wins a second term.

Likewise Pennsylvania, where in the west of the state white working-class voters could be what pushes the president over the line.

The one other reason that a Trump victory would not surprise me in the least is that Joe Biden is hardly an inspiring campaigner.

And this is the possibility that not only does Biden win, he wins big

Unlike 2016, when Donald Trump had a very clear message to the American people - he wanted to build a wall, he wanted to keep Muslims out, he wanted to renegotiate trade deals, he wanted to bring back manufacturing - in 2020 he's struggled to articulate what a second term would be about.

And after billions of dollars spent, you end up in total gridlocked, legal quagmire, America divided hell.