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OSPI Now Offering Anterior Approach Hip Replacement, AfterHours - weSRCH - 2 views

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    Orthopedic and Sports Performance Institute (OSPI) combines practice and comprehensive services focused on assisting patients in and around Arizona to live a ba..., Free Press Release Submission - OSPI Now Offering Anterior Approach Hip Replacement, AfterHours - weSRCH.
Skeptical Debunker

Human cells exhibit foraging behavior like amoebae and bacteria - 0 views

  • "As far as we can tell, this is the first time this type of behavior has been reported in cells that are part of a larger organism," says Peter T. Cummings, John R. Hall Professor of Chemical Engineering, who directed the study that is described in the March 10 issue of the Public Library of Science journal PLoS ONE. The discovery was the unanticipated result of a study the Cummings group conducted to test the hypothesis that the freedom with which different cancer cells move - a concept called motility - could be correlated with their aggressiveness: That is, the faster a given type of cancer cell can move through the body the more aggressive it is. "Our results refute that hypothesis—the correlation between motility and aggressiveness that we found among three different types of cancer cells was very weak," Cummings says. "In the process, however, we began noticing that the cell movements were unexpectedly complicated." Then the researchers' interest was piqued by a paper that appeared in the February 2008 issue of the journal Nature titled, "Scaling laws of marine predator search behaviour." The paper contained an analysis of the movements of a variety of radio-tagged marine predators, including sharks, sea turtles and penguins. The authors found that the predators used a foraging strategy very close to a specialized random walk pattern, called a Lévy walk, an optimal method for searching complex landscapes. At the end of the paper's abstract they wrote, "...Lévy-like behaviour seems to be widespread among diverse organisms, from microbes to humans, as a 'rule' that evolved in response to patchy resource distributions." This gave Cummings and his colleagues a new perspective on the cell movements that they were observing in the microscope. They adopted the basic assumption that when mammalian cells migrate they face problems, such as efficiently finding randomly distributed targets like nutrients and growth factors, that are analogous to those faced by single-celled organisms foraging for food. With this perspective in mind, Alka Potdar, now a post-doctoral fellow at Case Western Reserve University and the Cleveland Clinic, cultured cells from three human mammary epithelial cell lines on two-dimensional plastic plates and tracked the cell motions for two-hour periods in a "random migration" environment free of any directional chemical signals. Epithelial cells are found throughout the body lining organs and covering external surfaces. They move relatively slowly, at about a micron per minute which corresponds to two thousandths of an inch per hour. When Potdar carefully analyzed these cell movements, she found that they all followed the same pattern. However, it was not the Lévy walk that they expected, but a closely related search pattern called a bimodal correlated random walk (BCRW). This is a two-phase movement: a run phase in which the cell travels primarily in one direction and a re-orientation phase in which it stays in place and reorganizes itself internally to move in a new direction. In subsequent studies, currently in press, the researchers have found that several other cell types (social amoeba, neutrophils, fibrosarcoma) also follow the same pattern in random migration conditions. They have also found that the cells continue to follow this same basic pattern when a directional chemical signal is added, but the length of their runs are varied and the range of directions they follow are narrowed giving them a net movement in the direction indicated by the signal.
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    When cells move about in the body, they follow a complex pattern similar to that which amoebae and bacteria use when searching for food, a team of Vanderbilt researchers have found. The discovery has a practical value for drug development: Incorporating this basic behavior into computer simulations of biological processes that involve cell migration, such as embryo development, bone remodeling, wound healing, infection and tumor growth, should improve the accuracy with which these models can predict the effectiveness of untested therapies for related disorders, the researchers say.
Sullo Law

What are Defective Products? - 0 views

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    Defective products usually fall into one of three categories: Defectively Designed Products, Defectively Manufactured Products, and Defectively Marketed Products. Defectively Designed Products are products that possess a defect inherent to its design (i.e., a seat belt made out of paper would most...
wheelchairindia9

Save Internet - 0 views

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    The Internet has become an integral part of all of our lives. We use it to do our work, connect with people and gain knowledge about various subjects. As our representatives, many of you use it to gather research about the issues faced by your constituents, the challenges faced by different parts of our country, and the expert knowledge needed to legislate for India's future and shape our national decisions. Today, the Internet in our country is facing the danger of losing its neutrality, which is vital to ensure that it grows to reach many more of our fellow Indians - and the people who use it innovate further. In the interest of furthering this cause, we have launched a campaign with fellow Indians who wish to 'Save the Internet'. This letter is addressed to Parliamentarians who have already taken or are considering taking a position on the recent consultation paper released by the TRAI for Internet licensing and net neutrality. We are grateful for the support we have received and the various public statements made by several of you which cut across party lines. Through this letter we wish to point out the intent and purpose of saveinternet.wheelchairindia.com campaign and also the call for a larger network neutrality law in India.
Alan Rann

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assetinfinity1

Asset Infinity- Fixed Asset Tracking and Management App - 0 views

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Physical Therapy Software - 0 views

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emerson jone

Physical Therapy Software - 0 views

http://www.emrnews.com/ The medical world is currently undergoing a digital revolution. Paper records, for a long time the only way to keep track of patients, are being replaced by digital databas...

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sachin master

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Tattoo Removal Methods - 0 views

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    Interpret Tattoo Removal Methods let the manual or mechanistic. It involves the utilization of a specialised gel, usually mixed with nsaid thing. This is tattooed into the wound and is motivated to connector the ink to the gel and therefore be (leaked) out of the strip. Withal, this apply is sporadic and may really rise finish in scarring, changes in paper texture, keloids (scars collected of collagen), and more discolouration of the wound. Wicked pulsed lighted therapy is a new subject which uses high-intensity device pulsed light therapy, a gel is practical to the peel and a wand is waved over it. Spell this method is supposed to be less wrenching than laser treatments, it's also far author expensive.
Skeptical Debunker

Acupuncture lessens depression symptoms during pregnancy, study shows - 0 views

  • The study authors, led by Rachel Manber, PhD, professor of psychiatry and behavioral sciences, said they hope the results will raise awareness of the problem of depression during pregnancy and provide patients and physicians an alternative to antidepressants. "This standardized acupuncture protocol could be a viable treatment option for depression during pregnancy," they wrote in a paper that will appear in the March issue of Obstetrics & Gynecology. Up to 14 percent of pregnant women may have major depressive disorder, a condition characterized by feelings of dread, gloom and hopelessness, and a loss of interest in normally pleasurable activities. Some women suffer from depression before becoming pregnant, stop taking their medication and then experience a relapse; in other women, pregnancy itself may cause depression.
  • For this study, the researchers recruited 150 women whose pregnancies were between 12 and 30 weeks gestation and who met the criteria for major depressive disorder. The women were randomized to receive one of three treatments: acupuncture specific for depression; control acupuncture, during which needles were inserted in points not known to help alleviate depressive symptoms; or massage. All of the women received eight weeks of therapy and were assessed for depression at the four- and eight-week marks by an interviewer who was unaware of the treatment each woman received. The researchers found that women who received the depression-specific acupuncture experienced a bigger reduction in depression symptoms than the women in the other groups. The response rate — defined as having a 50 percent or greater reduction in symptoms — was 63 percent for the women receiving depression-specific acupuncture, compared with 44 percent for the women in the other two treatment groups combined. The researchers weren't surprised by what they found — a pilot study yielded similar results, and other studies have shown acupuncture is an effective treatment for depression in the general public — but they were pleased with the results. "I don't think that one-size-fits-all treatments are appropriate for everyone, but acupuncture should be considered as an option," said Lyell. "I hope that people will respect the rigorous methodology used in this blinded, randomized, controlled trial and accept the result: Traditional acupuncture was associated with a significant improvement in depression."
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    Acupuncture appears to be an effective way to reduce depression symptoms during pregnancy, according to a first-of-its-kind study from Stanford University School of Medicine researchers.
Skeptical Debunker

Traces of the past: Computer algorithm able to 'read' memories - 0 views

  • To explore how such memories are recorded, the researchers showed ten volunteers three short films and asked them to memorise what they saw. The films were very simple, sharing a number of similar features - all included a woman carrying out an everyday task in a typical urban street, and each film was the same length, seven seconds long. For example, one film showed a woman drinking coffee from a paper cup in the street before discarding the cup in a litter bin; another film showed a (different) woman posting a letter. The volunteers were then asked to recall each of the films in turn whilst inside an fMRI scanner, which records brain activity by measuring changes in blood flow within the brain. A computer algorithm then studied the patterns and had to identify which film the volunteer was recalling purely by looking at the pattern of their brain activity. The results are published in the journal Current Biology. "The algorithm was able to predict correctly which of the three films the volunteer was recalling significantly above what would be expected by chance," explains Martin Chadwick, lead author of the study. "This suggests that our memories are recorded in a regular pattern." Although a whole network of brain areas support memory, the researchers focused their study on the medial temporal lobe, an area deep within the brain believed to be most heavily involved in episodic memory. It includes the hippocampus - an area which Professor Maguire and colleagues have studied extensively in the past. They found that the key areas involved in recording the memories were the hippocampus and its immediate neighbours. However, the computer algorithm performed best when analysing activity in the hippocampus itself, suggesting that this is the most important region for recording episodic memories. In particular, three areas of the hippocampus - the rear right and the front left and front right areas - seemed to be involved consistently across all participants. The rear right area had been implicated in the earlier study, further enforcing the idea that this is where spatial information is recorded. However, it is still not clear what role the front two regions play.
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    Computer programs have been able to predict which of three short films a person is thinking about, just by looking at their brain activity. The research, conducted by scientists at the Wellcome Trust Centre for Neuroimaging at UCL (University College London), provides further insight into how our memories are recorded.
anonymous

Ditch Poor Financial Management Through Enhanced Spiritual Health - 1 views

The world is filled with silent wails from people who cry prayers of "I need money". Money is such a complicated yet easy thing. It is just small sheets of paper with photos and specific inscriptio...

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started by anonymous on 23 Dec 14 no follow-up yet
alishacarterrw

Autism is not mental retardation - 1 views

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    The term 'Autism' didn't arrive in the Indian literature until the year 1959. Following the next decade, there were several papers published on the matter. However, it wasn't until the 1980s when this 'word' started gaining serious ground in terms of neurosciences.
robby6535

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