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Johnny James

Origin of human intestinal immune system - 1 views

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started by Johnny James on 12 Feb 14
  • Johnny James
     
    Settled in the human gut trillions of harmful bacteria affect human health exhibit persistent threat, intestinal innate immune function in our body and microbial ecosystems establish a protective barrier, recently, from researchers through research, identify the human intestinal immune system and development of infrastructure. Intestinal immune special structure, such as gut-associated lymphoid tissue (GALT), which is the main component of the intestinal immune system.
    In mice, the cell aggregates called cryptopatches development is GALT loci. Through biological engineering researcher makes the human intestinal immune system respectively to two closely related strains of mice
    (egf elisa kit), when the presence of the human body in cryptopatches the human GALT structure will be formed, and the structure can promote human GALT intestinal immune functions, including functions to produce specific antibodies.
    The researchers said that, our model reveals the development of human GALT a new aspect, but also describes the effects of the human intestinal immune system of the two sub-processes. In humans and mice and cryptopatches working principle of the body appears to be the same. This study confirms, humanized chimeric mice showed normal body can be the human immune system function, but the study also raises a lot of research progress, which will help promote research in gastrointestinal function, further research who will continue to use an animal model to test whether this regenerative therapy can repair damage in the human organism GALT. Related research funded by the NIH and other agencies.

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