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Glucomannan is a water-soluble fiber, which refers to a group of carbohydrates that resist digestion. It is a combination of glucose, the basic sugar molecule, and mannose, another type of sugar. They are joined through a material called glucosidic bonds. Glucomannan is said to have the highest molecular weight and strongest viscosity of any known dietary fiber. Viscous fibers form a thick gel in liquid, such as the environment found in your gut. This function of fiber makes your stomach empty slower and slows down the process of absorbing some nutrients in the small intestine. Far beyond its nearest "competitor," glucomannan is said to absorb up to 200 times its weight in water as it forms the viscous gel in your belly.

Supplements which block the absorption of fat are effective at treating obesity because fat has significantly more calories than other nutrients. Indeed, 1 gram of fat has 9 calories, whereas 1 gram of protein or carbohydrate has just 4 calories.