encontraras una serie de herramientas y aplicaciones utiles para analisis bibliometri. algunas estan en fase beta asi que aplrovechen

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aplicacion de un metodo en especifico

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buscador de informacion de microsoft

interfase que permite ver varias bases de datos de pubmed

permite buscar articulos de interes relacionados a un tema en particular interfascweb que permite mineria de texto eliminando ruido informativo y no mas de 1000 articulos

catalogo para los analisis de bibliometria, muestra tendencias y publicaciones, para genomica y biomedica

proporciona los recursos, indicadores, indice de colaboracion, instituciones, 

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buscador que elimina el ruido informatico, mas especializado hacia las ciencias bilogicas

tsauro

opciones de campo sistema de informacion que conjunta varias bases de datos solo en red UNAM

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articulo que menciona a las aicdemias organicas de forma general

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articulo sobe acidemia propionica

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My watch list my.bionity.com   Login     Back to List |HomeEncyclopediaOrganic_acidemia Organic acidemia Organic acidemia, also called organic aciduria, is a term used to classify a group of metabolic disorders which disrupt normal amino acid metabolism, particularly branched-chain amino acids, causing a buildup of acids which are usually not present.[1] The four main types of organic acidemia are: methylmalonic acidemia, propionic acidemia, isovaleric acidemia, and maple syrup urine disease.[1] Contents 1 Terminology 2 Diagnosis and Symptoms 3 Cause 4 Treatment 5 References Terminology Organic acids refer to the amino acids and certain odd-chained fatty acids which are affected by these disorders. The branched-chain amino acids include isoleucine, leucine and valine.[1] Diagnosis and Symptoms Organic acidemias are usually always diagnosed in infancy, characterized by urinary excretion of abnormal amounts or types of organic acids. The diagnosis is usually made by detecting an abnormal pattern of organic acids in a urine sample by gas chromatography - mass spectrometry. In some conditions, the urine is always abnormal, in others the characteristic substances are only present intermittently. Many of the organic acidemias are detectable by newborn screening with tandem mass spectrometry.[2] These disorders vary in their prognosis, from manageable to fatal, and usually affect more than one organ system, especially the central nervous system. Neurological damage and developmental delay are common factors in diagnosis, with associated symptoms ranging from poor feeding to slow growth, lethargy, vomiting, dehydration, malnutrition, hypoglycemia, hypotonia, metabolic acidosis, ketoacidosis, hyperammonemia, and if left untreated, death. Cause Most of the organic acidemias result from defective autosomal genes for various enzymes important to amino acid metabolism. Neurological and physiological harm is caused by this impaired ability to synthesize a key enzy

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