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As Omicron surges through the community, getting the right answer from a Rapid Antigen Test (RAT) is not as straightforward as reading one or two lines off the kit. RATs are a convenient diagnostic tool to detect COVID virus fragments in nasal secretions or saliva. They are designed to be self-administered and give an answer in minutes. Detecting infection early is critical to preventing spread and allowing persons at risk of severe disease to get timely access to close monitoring and new life-saving therapies. As governments plan to distribute tens of millions of RAT kits to schools and workplaces in coming weeks to help Australians work and study safely, it is important that we understand how to best use this diagnostic tool to reduce transmission and unnecessary disruptions to our lives and economy.