Human Microbiome and Microbiota - 0 views
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The human microbiota consists of the entire collection of microbes that live in and on the body. In fact, there are 10 times as many microbial inhabitants of the body than there are body cells. Study of the human microbiome is inclusive of inhabitant microbes as well as the entire genomes of the body's microbial communities. These microbes reside in distinct locations in the ecosystem of the human body and perform important functions that are necessary for healthy human development.
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Microbes of the BodyMicroscopic organisms that inhabit the body include archaea, bacteria, fungi, protists, and viruses. Microbes start to colonize the body from the moment of birth. An individual's microbiome changes in number and type throughout his or her lifetime, with the numbers of species increasing from birth to adulthood and decreasing in old age. These microbes are unique from person to person and can be impacted by certain activities, such as hand washing or taking antibiotics. Bacteria are the most numerous microbes in the human microbiome.
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Human skin is populated by a number of different microbes that reside on the surface of the skin, as well as within glands and hair. Our skin is in constant contact with our external environment and serves as the body's first line of defense against potential pathogens. Skin microbiota help to prevent pathogenic microbes from colonizing the skin by occupying skin surfaces. They also help to educate our immune system by alerting immune cells to the presence of pathogens and initiating an immune response
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The human gut microbiome is diverse and dominated by trillions of bacteria with as many as one-thousand different bacterial species. These microbes thrive in the harsh conditions of the gut and are heavily involved in maintaining healthy nutrition, normal metabolism, and proper immune function. They aid in the digestion of non-digestible carbohydrates, the metabolism of bile acid and drugs, and in the synthesis of amino acids and many vitamins. A number of gut microbes also produce antimicrobial substances that protect against pathogenic bacteria.
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Microbiota of the oral cavity number in the millions and include archaea, bacteria, fungi, protists, and viruses. These organisms exist together and most in a mutualistic relationship with the host, where both the microbes and the host benefit from the relationship. While the majority of oral microbes are beneficial, preventing harmful microbes from colonizing the mouth, some have been known to become pathogenic in response to environmental changes. Bacteria are the most numerous of the oral microbes and include Streptococcus, Actinomyces, Lactobacterium, Staphylococcus, and Propionibacterium.