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Javier E

Who Needs Math? - The Monkey Cage - 1 views

  • by Larry Bartels on April 9, 2013
  • “When something new is encountered, the follow-up steps usually require mathematical and statistical methods to move the analysis forward.” At that point, he suggests finding a collaborator
  • But technical expertise in itself is of little avail: ”The annals of theoretical biology are clogged with mathematical models that either can be safely ignored or, when tested, fail. Possibly no more than 10% have any lasting value. Only those linked solidly to knowledge of real living systems have much chance of being used.”
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  • . If you’re going to talk about economics at all, you need some sense of how magnitudes play off against each other, which is the only way to have a chance of seeing how the pieces fit together.
  • [M]aybe the thing to say is that higher math isn’t usually essential; arithmetic is.
  • My own work has become rather less mathematical over the course of my career. When people ask why, I usually say that as I have come to learn more about politics, the “sophisticated” wrinkles have seemed to distract more than they adde
  • “Seeing how the pieces fit together” requires “some sense of how magnitudes play off against each other.” But, paradoxically, ”higher math” can get in the way of “mathematical intuition” about magnitudes. Formal theory is often couched in purely qualitative terms: under such and such conditions, more X should produce more Y. And quantitative analysis—which ought to focus squarely on magnitudes—is less likely to do so the more it is justified and valued on technical rather than substantive grounds.
  • I recently spent some time doing an informal meta-analysis of studies of the impact of campaign advertising. At the heart of that literature is a pretty simple question: how much does one more ad contribute to the sponsoring candidate’s vote share? Alas, most of the studies I reviewed provided no intelligible answer to that question; and the correlation between methodological “sophistication” (logarithmic transformations, multinomial logits, fixed effects, distributed lag models) and intelligibility was decidedly negative. The authors of these studies rarely seemed to know or care what their results implied about the magnitude of the effect, as long as those results could be billed as “statistically significant.
sissij

How humans bond: The brain chemistry revealed: New research finds that dopamine is involved in human bonding -- ScienceDaily - 0 views

  • Northeastern University psychology professor Lisa Feldman Barrett found, for the first time, that the neurotransmitter dopamine is involved in human bonding, bringing the brain's reward system into our understanding of how we form human attachments.
  • To conduct the study, the researchers turned to a novel technology: a machine capable of performing two types of brain scans simultaneously -- functional magnetic resonance imaging, or fMRI, and positron emission tomography, or PET.
  • Barrett's team focused on the neurotransmitter dopamine, a chemical that acts in various brain systems to spark the motivation necessary to work for a reward.
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  • The mothers who were more synchronous with their own infants showed both an increased dopamine response when viewing their child at play and stronger connectivity within the medial amygdala network.
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    I think this article is very interesting because it is trying to explain human social behaviors through chemistry and biology. Although there are a lot of factors in human science, by converting it to a natural science problem, we can make the question easier to answer. It also shows the interaction between different subfields of science. --Sissi (2/20/2017)
kortanekev

The Crisis Of Market Fundamentalism - 0 views

  • At the same time, a second, more momentous, intellectual revolution will be needed regarding government intervention in social outcomes and economic structures. Market fundamentalism conceals a profound contradiction. Free trade, technological progress, and other forces that promote economic “efficiency” are presented as beneficial to society, even if they harm individual workers or businesses, because growing national incomes allow winners to compensate losers, ensuring that nobody is left worse off.
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    This article calls into question the definition of a "good outcome." Who does it benefit? Does some solution benefit the masses, but take advantage of a minority? The highlighted passage shows the ideal of pareto-efficiency, when no one is left worse off when a change has been made. So even if only one group has been benefitted, the other groups are not worse off (unless that calls into account discrimination etc.).  Evie K 3/1/17
Javier E

Eric A. Posner Reviews Jim Manzi's "Uncontrolled" | The New Republic - 0 views

  • Most urgent questions of public policy turn on empirical imponderables, and so policymakers fall back on ideological predispositions or muddle through. Is there a better way?
  • The gold standard for empirical research is the randomized field trial (RFT).
  • The RFT works better than most other types of empirical investigation. Most of us use anecdotes or common sense empiricism to make inferences about the future, but psychological biases interfere with the reliability of these methods
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  • Serious empiricists frequently use regression analysis.
  • Regression analysis is inferior to RFT because of the difficulty of ruling out confounding factors (for example, that a gene jointly causes baldness and a preference for tight hats) and of establishing causation
  • RFT has its limitations as well. It is enormously expensive because you must (usually) pay a large number of people to participate in an experiment, though one can obtain a discount if one uses prisoners, especially those in a developing country. In addition, one cannot always generalize from RFTs.
  • academic research proceeds in fits and starts, using RFT when it can, but otherwise relying on regression analysis and similar tools, including qualitative case studies,
  • businesses also use RFT whenever they can. A business such as Wal-Mart, with thousands of stores, might try out some innovation like a new display in a random selection of stores, using the remaining stores as a control group
  • Manzi argues that the RFT—or more precisely, the overall approach to empirical investigation that the RFT exemplifies—provides a way of thinking about public policy. Thi
  • the universe is shaky even where, as in the case of physics, “hard science” plays the dominant role. The scientific method cannot establish truths; it can only falsify hypotheses. The hypotheses come from our daily experience, so even when science prunes away intuitions that fail the experimental method, we can never be sure that the theories that remain standing reflect the truth or just haven’t been subject to the right experiment. And even within its domain, the experimental method is not foolproof. When an experiment contradicts received wisdom, it is an open question whether the wisdom is wrong or the experiment was improperly performed.
  • The book is less interested in the RFT than in the limits of empirical knowledge. Given these limits, what attitude should we take toward government?
  • Much of scientific knowledge turns out to depend on norms of scientific behavior, good faith, convention, and other phenomena that in other contexts tend to provide an unreliable basis for knowledge.
  • Under this view of the world, one might be attracted to the cautious conservatism associated with Edmund Burke, the view that we should seek knowledge in traditional norms and customs, which have stood the test of time and presumably some sort of Darwinian competition—a human being is foolish, the species is wise. There are hints of this worldview in Manzi’s book, though he does not explicitly endorse it. He argues, for example, that we should approach social problems with a bias for the status quo; those who seek to change it carry the burden of persuasion. Once a problem is identified, we should try out our ideas on a small scale before implementing them across society
  • Pursuing the theme of federalism, Manzi argues that the federal government should institutionalize policy waivers, so states can opt out from national programs and pursue their own initiatives. A state should be allowed to opt out of federal penalties for drug crimes, for example.
  • It is one thing to say, as he does, that federalism is useful because we can learn as states experiment with different policies. But Manzi takes away much of the force of this observation when he observes, as he must, that the scale of many of our most urgent problems—security, the economy—is at the national level, so policymaking in response to these problems cannot be left to the states. He also worries about social cohesion, which must be maintained at a national level even while states busily experiment. Presumably, this implies national policy of some sort
  • Manzi’s commitment to federalism and his technocratic approach to policy, which relies so heavily on RFT, sit uneasily together. The RFT is a form of planning: the experimenter must design the RFT and then execute it by recruiting subjects, paying them, and measuring and controlling their behavior. By contrast, experimentation by states is not controlled: the critical element of the RFT—randomization—is absent.
  • The right way to go would be for the national government to conduct experiments by implementing policies in different states (or counties or other local units) by randomizing—that is, by ordering some states to be “treatment” states and other states to be “control” states,
  • Manzi’s reasoning reflects the top-down approach to social policy that he is otherwise skeptical of—although, to be sure, he is willing to subject his proposals to RFTs.
Javier E

Philosophy Is Not a Science - NYTimes.com - 0 views

  • what objective knowledge can philosophy bring that is not already determinable by science?
  • numerous philosophers have come to believe, in concert with the prejudices of our age, that only science holds the potential to solve persistent philosophical mysteries as the nature of truth, life, mind, meaning, justice, the good and the beautiful.
  • myriad contemporary philosophers are perfectly willing to offer themselves up as intellectual servants or ushers of scientific progress. Their research largely functions as a spearhead for scientific exploration and as a balm for making those pursuits more palpable and palatable to the wider population.
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  • While science and philosophy do at times overlap, they are fundamentally different approaches to understanding. So philosophers should not add to the conceptual confusion that subsumes all knowledge into science.
  • various disciplines we ordinarily treat as science are at least as — if not more —philosophical than scientific. Take for example mathematics, theoretical physics, psychology and economics. These are predominately rational conceptual disciplines. That is, they are not chiefly reliant on empirical observation. For unlike science, they may be conducted while sitting in an armchair with eyes closed.
  • unlike empirical observations, which may be mistaken or incomplete, philosophical findings depend primarily on rational and logical principles. As such, whereas science tends to alter and update its findings day to day through trial and error, logical deductions are timeless.
  • while mathematics is empirically testable at such rudimentary levels, it stops being so in its purest forms, like analysis and number theory. Proofs in these areas are conducted entirely conceptually
  • Logically fallacious arguments can be rather sophisticated and persuasive. But they are nevertheless invalid and always will be. Exposing such errors is part of philosophy’s stock and trade.
  • Wittgenstein showed that an ordinary word such as “game” is used consistently in myriad contrasting ways without possessing any essential unifying definition. Though this may seem impossible, the meaning of such terms is actually determined by their contextual usage
  • Ultimately as a result of Wittgenstein’s philosophy, we know that natural language is a public phenomenon that cannot logically be invented in isolation.
  • These are essentially conceptual clarifications. And as such, they are relatively timeless philosophical truths.
  • This is also why jurisprudence qualifies as an objective body of knowledge
  • Supreme Court justices are not so much scientific as philosophical experts on the nature of justice. And that is not to say their expertise does not count as genuine knowledge. In the best cases, it rises to the loftier level of wisdom
  • Though philosophy does sometimes employ thought experiments, these aren’t actually scientific, for they are conducted entirely in the imagination.
  • in ethics, science cannot necessarily tell us what to value
  • evidence of how most people happen to be does not necessarily tell us everything about how we should aspire to be. For how we should aspire to be is a conceptual question, namely, of how we ought to act, as opposed to an empirical question of how we do act.
Javier E

Eric Kandel's Visions - The Chronicle Review - The Chronicle of Higher Education - 0 views

  • Judith, "barely clothed and fresh from the seduction and slaying of Holofernes, glows in her voluptuousness. Her hair is a dark sky between the golden branches of Assyrian trees, fertility symbols that represent her eroticism. This young, ecstatic, extravagantly made-up woman confronts the viewer through half-closed eyes in what appears to be a reverie of orgasmic rapture," writes Eric Kandel in his new book, The Age of Insight. Wait a minute. Writes who? Eric Kandel, the Nobel-winning neuroscientist who's spent most of his career fixated on the generously sized neurons of sea snails
  • Kandel goes on to speculate, in a bravura paragraph a few hundred pages later, on the exact neurochemical cognitive circuitry of the painting's viewer:
  • "At a base level, the aesthetics of the image's luminous gold surface, the soft rendering of the body, and the overall harmonious combination of colors could activate the pleasure circuits, triggering the release of dopamine. If Judith's smooth skin and exposed breast trigger the release of endorphins, oxytocin, and vasopressin, one might feel sexual excitement. The latent violence of Holofernes's decapitated head, as well as Judith's own sadistic gaze and upturned lip, could cause the release of norepinephrine, resulting in increased heart rate and blood pressure and triggering the fight-or-flight response. In contrast, the soft brushwork and repetitive, almost meditative, patterning may stimulate the release of serotonin. As the beholder takes in the image and its multifaceted emotional content, the release of acetylcholine to the hippocampus contributes to the storing of the image in the viewer's memory. What ultimately makes an image like Klimt's 'Judith' so irresistible and dynamic is its complexity, the way it activates a number of distinct and often conflicting emotional signals in the brain and combines them to produce a staggeringly complex and fascinating swirl of emotions."
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  • His key findings on the snail, for which he shared the 2000 Nobel Prize in Physiology or Medicine, showed that learning and memory change not the neuron's basic structure but rather the nature, strength, and number of its synaptic connections. Further, through focus on the molecular biology involved in a learned reflex like Aplysia's gill retraction, Kandel demonstrated that experience alters nerve cells' synapses by changing their pattern of gene expression. In other words, learning doesn't change what neurons are, but rather what they do.
  • In Search of Memory (Norton), Kandel offered what sounded at the time like a vague research agenda for future generations in the budding field of neuroaesthetics, saying that the science of memory storage lay "at the foothills of a great mountain range." Experts grasp the "cellular and molecular mechanisms," he wrote, but need to move to the level of neural circuits to answer the question, "How are internal representations of a face, a scene, a melody, or an experience encoded in the brain?
  • Since giving a talk on the matter in 2001, he has been piecing together his own thoughts in relation to his favorite European artists
  • The field of neuroaesthetics, says one of its founders, Semir Zeki, of University College London, is just 10 to 15 years old. Through brain imaging and other studies, scholars like Zeki have explored the cognitive responses to, say, color contrasts or ambiguities of line or perspective in works by Titian, Michelangelo, Cubists, and Abstract Expressionists. Researchers have also examined the brain's pleasure centers in response to appealing landscapes.
  • it is fundamental to an understanding of human cognition and motivation. Art isn't, as Kandel paraphrases a concept from the late philosopher of art Denis Dutton, "a byproduct of evolution, but rather an evolutionary adaptation—an instinctual trait—that helps us survive because it is crucial to our well-being." The arts encode information, stories, and perspectives that allow us to appraise courses of action and the feelings and motives of others in a palatable, low-risk way.
  • "as far as activity in the brain is concerned, there is a faculty of beauty that is not dependent on the modality through which it is conveyed but which can be activated by at least two sources—musical and visual—and probably by other sources as well." Specifically, in this "brain-based theory of beauty," the paper says, that faculty is associated with activity in the medial orbitofrontal cortex.
  • It also enables Kandel—building on the work of Gombrich and the psychoanalyst and art historian Ernst Kris, among others—to compare the painters' rendering of emotion, the unconscious, and the libido with contemporaneous psychological insights from Freud about latent aggression, pleasure and death instincts, and other primal drives.
  • Kandel views the Expressionists' art through the powerful multiple lenses of turn-of-the-century Vienna's cultural mores and psychological insights. But then he refracts them further, through later discoveries in cognitive science. He seeks to reassure those who fear that the empirical and chemical will diminish the paintings' poetic power. "In art, as in science," he writes, "reductionism does not trivialize our perception—of color, light, and perspective—but allows us to see each of these components in a new way. Indeed, artists, particularly modern artists, have intentionally limited the scope and vocabulary of their expression to convey, as Mark Rothko and Ad Reinhardt do, the most essential, even spiritual ideas of their art."
  • The author of a classic textbook on neuroscience, he seems here to have written a layman's cognition textbook wrapped within a work of art history.
  • "our initial response to the most salient features of the paintings of the Austrian Modernists, like our response to a dangerous animal, is automatic. ... The answer to James's question of how an object simply perceived turns into an object emotionally felt, then, is that the portraits are never objects simply perceived. They are more like the dangerous animal at a distance—both perceived and felt."
  • If imaging is key to gauging therapeutic practices, it will be key to neuroaesthetics as well, Kandel predicts—a broad, intense array of "imaging experiments to see what happens with exaggeration, distorted faces, in the human brain and the monkey brain," viewers' responses to "mixed eroticism and aggression," and the like.
  • while the visual-perception literature might be richer at the moment, there's no reason that neuroaesthetics should restrict its emphasis to the purely visual arts at the expense of music, dance, film, and theater.
  • although Kandel considers The Age of Insight to be more a work of intellectual history than of science, the book summarizes centuries of research on perception. And so you'll find, in those hundreds of pages between Kandel's introduction to Klimt's "Judith" and the neurochemical cadenza about the viewer's response to it, dossiers on vision as information processing; the brain's three-dimensional-space mapping and its interpretations of two-dimensional renderings; face recognition; the mirror neurons that enable us to empathize and physically reflect the affect and intentions we see in others; and many related topics. Kandel elsewhere describes the scientific evidence that creativity is nurtured by spells of relaxation, which foster a connection between conscious and unconscious cognition.
  • Zeki's message to art historians, aesthetic philosophers, and others who chafe at that idea is twofold. The more diplomatic pitch is that neuroaesthetics is different, complementary, and not oppositional to other forms of arts scholarship. But "the stick," as he puts it, is that if arts scholars "want to be taken seriously" by neurobiologists, they need to take advantage of the discoveries of the past half-century. If they don't, he says, "it's a bit like the guys who said to Galileo that we'd rather not look through your telescope."
  • Matthews, a co-author of The Bard on the Brain: Understanding the Mind Through the Art of Shakespeare and the Science of Brain Imaging (Dana Press, 2003), seems open to the elucidations that science and the humanities can cast on each other. The neural pathways of our aesthetic responses are "good explanations," he says. But "does one [type of] explanation supersede all the others? I would argue that they don't, because there's a fundamental disconnection still between ... explanations of neural correlates of conscious experience and conscious experience" itself.
  • There are, Matthews says, "certain kinds of problems that are fundamentally interesting to us as a species: What is love? What motivates us to anger?" Writers put their observations on such matters into idiosyncratic stories, psychologists conceive their observations in a more formalized framework, and neuroscientists like Zeki monitor them at the level of functional changes in the brain. All of those approaches to human experience "intersect," Matthews says, "but no one of them is the explanation."
  • "Conscious experience," he says, "is something we cannot even interrogate in ourselves adequately. What we're always trying to do in effect is capture the conscious experience of the last moment. ... As we think about it, we have no way of capturing more than one part of it."
  • Kandel sees art and art history as "parent disciplines" and psychology and brain science as "antidisciplines," to be drawn together in an E.O. Wilson-like synthesis toward "consilience as an attempt to open a discussion between restricted areas of knowledge." Kandel approvingly cites Stephen Jay Gould's wish for "the sciences and humanities to become the greatest of pals ... but to keep their ineluctably different aims and logics separate as they ply their joint projects and learn from each other."
anonymous

What Isn't for Sale? - Magazine - The Atlantic - 0 views

  • When we decide that certain goods may be bought and sold, we decide, at least implicitly, that it is appropriate to treat them as commodities, as instruments of profit and use. But not all goods are properly valued in this way. The most obvious example is human beings. Slavery was appalling because it treated human beings as a commodity, to be bought and sold at auction. Such treatment fails to value human beings as persons, worthy of dignity and respect; it sees them as instruments of gain and objects of use. Something similar can be said of other cherished goods and practices. We don’t allow children to be bought and sold, no matter how difficult the process of adoption can be or how willing impatient prospective parents might be. Even if the prospective buyers would treat the child responsibly, we worry that a market in children would express and promote the wrong way of valuing them. Children are properly regarded not as consumer goods but as beings worthy of love and care. Or consider the rights and obligations of citizenship. If you are called to jury duty, you can’t hire a substitute to take your place. Nor do we allow citizens to sell their votes, even though others might be eager to buy them. Why not? Because we believe that civic duties are not private property but public responsibilities. To outsource them is to demean them, to value them in the wrong way. These examples illustrate a broader point: some of the good things in life are degraded if turned into commodities. So to decide where the market belongs, and where it should be kept at a distance, we have to decide how to value the goods in question—health, education, family life, nature, art, civic duties, and so on. These are moral and political questions, not merely economic ones. To resolve them, we have to debate, case by case, the moral meaning of these goods, and the proper way of valuing them.
Javier E

What Is College For? - NYTimes.com - 0 views

  • 74 percent of graduates from four-year colleges say that their education was “very useful in helping them grow intellectually.”
  • When, as is often the case in business education and teacher training, practical skills far outweigh theoretical understanding, we are moving beyond the intellectual culture that defines higher education
  • This lack of academic engagement is real, even among schools with the best students and the best teachers, and it increases dramatically as the quality of the school decreases.  But it results from a basic misunderstanding — by both students and teachers — of what colleges are for.
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  • First of all, they are not simply for the education of students.  This is an essential function, but the raison d’être of a college is to nourish a world of intellectual culture; that is, a world of ideas, dedicated to what we can know scientifically, understand humanistically, or express artistically.  In our society, this world is mainly populated by members of college faculties: scientists, humanists, social scientists (who straddle the humanities and the sciences properly speaking), and those who study the fine arts. Law, medicine and engineering are included to the extent that they are still understood as “learned professions,” deploying practical skills that are nonetheless deeply rooted in scientific knowledge or humanistic understanding
  • there are serious concerns about the quality of this experience.  In particular, the university curriculum leaves students disengaged from the material they are supposed to be learning.  They see most of their courses as intrinsically “boring,” of value only if they provide training relevant to future employment or if the teacher has a pleasing (amusing, exciting, “relevant”) way of presenting the material. As a result, students spend only as much time as they need to get what they see as acceptable grades (on average, about 12 to 14 hour a week for all courses combined).  Professors have ceased to expect genuine engagement from students and often give good grades (B or better) to work that is at best minimally adequate.
  • Our support for higher education makes sense only if we regard this intellectual culture as essential to our society
  • This has important consequences for how we regard what goes on in college classrooms.  Teachers need to see themselves as, first of all, intellectuals, dedicated to understanding poetry, history, human psychology, physics, biology — or whatever is the focus of their discipline.  But they also need to realize that this dedication expresses not just their idiosyncratic interest in certain questions but a conviction that those questions have general human significance, even apart from immediately practical applications.  This is why a discipline requires not just research but also teaching
  • Students, in turn, need to recognize that their college education is above all a matter of opening themselves up to new dimensions of knowledge and understanding.  Teaching is not a matter of (as we too often say) “making a subject (poetry, physics, philosophy) interesting” to students but of students coming to see how such subjects are intrinsically interesting.  It is more a matter of students moving beyond their interests than of teachers fitting their subjects to interests that students already have.   Good teaching does not make a course’s subject more interesting; it gives the students more interests — and so makes them more interesting.
Duncan H

Apple, America and a Squeezed Middle Class - NYTimes.com - 0 views

  • When Barack Obama joined Silicon Valley’s top luminaries for dinner in California last February, each guest was asked to come with a question for the president.
  • what would it take to make iPhones in the United States?
  • Not long ago, Apple boasted that its products were made in America. Today, few are. Almost all of the 70 million iPhones, 30 million iPads and 59 million other products Apple sold last year were manufactured overseas. Why can’t that work come home? Mr. Obama asked. Mr. Jobs’s reply was unambiguous. “Those jobs aren’t coming back,” he said, according to another dinner guest. The president’s question touched upon a central conviction at Apple. It isn’t just that workers are cheaper abroad. Rather, Apple’s executives believe the vast scale of overseas factories as well as the flexibility, diligence and industrial skills of foreign workers have so outpaced their American counterparts that “Made in the U.S.A.” is no longer a viable option for most Apple products. Apple has become one of the best-known, most admired and most imitated companies on earth, in part through an unrelenting mastery of global operations. Last year, it earned over $400,000 in profit per employee, more than Goldman Sachs, Exxon Mobil or Google. However, what has vexed Mr. Obama as well as economists and policy makers is that Apple — and many of its high-technology peers — are not nearly as avid in creating American jobs as other famous companies were in their heydays.
Javier E

Does Technology Affect Happiness? - NYTimes.com - 1 views

  • How is technology affecting their happiness and emotional development?
  • The answer, in the peer-reviewed study of the online habits of girls ages 8 to 12, is that those who say they spend considerable amounts of time using multimedia describe themselves in ways that suggest they are less happy and less socially comfortable than peers who say they spend less time on screens.
  • Among the crucial questions that the researchers were not able to answer is whether the heavy use of media was the cause for the relative unhappiness or whether girls who are less happy to begin with are drawn to heavy use of media, in effect retreating to a virtual world.
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  • on a basic, even primitive level, girls need to experience the full pantheon of communication that comes from face-to-face contact, such as learning to read body language, and subtle facial and verbal cues.
  • The fact that the study was based on an online survey gave pause to some academics. While they said the paper raised good questions, they also expressed concern about giving it too much weight, given that the researchers were not able to follow up with the survey subjects to get important context, including their family circumstances, income or ethnicity.
  • The researchers found that the average amount of media use by the girls surveyed was 6.9 hours per day, a figure that included reading as well as screen time. The average amount of time spent in face-to-face social settings was 2.1 hours, a figure that did not include classroom time.
  • Ms. Gray said, she worries that her daughter, who is using Facebook more, is playing out her social life online sometimes without the benefits of the full emotional range that comes from face-to-face interaction.
Duncan H

Study Suggests Way to Delay Age-Related Changes - WSJ.com - 0 views

  • Article Video Comments (54) more in Health & Wellness | Find New $LINKTEXTFIND$ »
  • Scientists may have found a way to put off some conditions of aging, according to a study in which they postponed or even prevented such afflictions as cataracts and wrinkle-inducing fat loss in mice by removing cells that had stopped dividing.
  • Most young, healthy cells divide continuously in order to keep body tissues and organs functioning properly, but eventually stop splitting—a state called senescence—and are replaced by others. Senescence occurs throughout life, but people's ability to clear such cells from their bodies decreases with age, leading to a buildup.
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  • "If you could clear senescent cells, you perhaps could treat age-related diseases as a group rather than individually," said Jan van Deursen, senior author of the paper and a professor in the departments of biochemistry and pediatric and adolescent medicine at Mayo.
  • When cells become senescent, they produce harmful compounds such as those that cause inflammation. Chronic tissue inflammation with aging is thought to underlie dementia, atherosclerosis and diabetes, among other ills,
  • Because senescence is believed to have developed as a defense against cancer, in which cells divide uncontrollably, simply halting the process could be dangerous. But scientists have wondered for decades if the damage inflicted by senescent cells could be stopped if they were removed from the body altogether, or if the harmful substances they produced were neutralized.
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    This seems like a question of a lesser of two evils, but it will be interesting to see where the research goes from here.
Javier E

Worldly Philosophers Wanted - NYTimes.com - 0 views

  • Keynes himself was driven by a powerful vision of capitalism. He believed it was the only system that could create prosperity, but it was also inherently unstable and so in need of constant reform. This vision caught the imagination of a generation that had experienced the Great Depression and World War II and helped drive policy for nearly half a century.
  • Friedrich Hayek and Milton Friedman, who envisioned an ideal economy involving isolated individuals bargaining with one another in free markets. Government, they contended, usually messes things up. Overtaking a Keynesianism that many found inadequate to the task of tackling the stagflation of the 1970s, this vision fueled neoliberal and free-market conservative agendas of governments around the world.
  • It took extensive government action to prevent another Great Depression, while the enormous rewards received by bankers at the heart of the meltdown have led many to ask whether unfettered capitalism produced an equitable distribution of wealth. We clearly need a new, alternative vision of capitalism. But thanks to decades of academic training in the “dentistry” approach to economics, today’s Keynes or Friedman is nowhere to be found.
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  • To refuse to discuss ideas such as types of capitalism deprives us of language with which to think about these problems. It makes it easier to stop thinking about what the economic system is for and in whose interests it is working.
  • Perhaps the protesters occupying Wall Street are not so misguided after all. The questions they raise — how do we deal with the local costs of global downturns? Is it fair that those who suffer the most from such downturns have their safety net cut, while those who generate the volatility are bailed out by the government? — are the same ones that a big-picture economic vision should address. If economists want to help create a better world, they first have to ask, and try to answer, the hard questions that can shape a new vision of capitalism’s potential.
Javier E

I Was Wrong, and So Are You - Magazine - The Atlantic - 1 views

  • The proper inference from our work is not that one group is more enlightened, or less. It’s that “myside bias”—the tendency to judge a statement according to how conveniently it fits with one’s settled position—is pervasive among all of America’s political groups. The bias is seen in the data, and in my actions.
  • we tabulated the average number of incorrect answers for each ideological group. On average, those who described themselves as progressive (or “very liberal”) got 5.3 of the 8 questions wrong, liberal 4.7, moderate 3.7, conservative 1.7, very conservative 1.3, and libertarian 1.4. These were the results published in Econ Journal Watch and broadcast in The Wall Street Journal.
  • You may have noticed that several of the statements we analyzed implicitly challenge positions held by the left, while none specifically challenges conservative or libertarian positions. A great deal of research shows that people are more likely to heed information that supports their prior positions, and discard or discount contrary information.
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  • Psychologists would count this tendency as a manifestation of “myside bias,” or “confirmation bias.”
  • A full tabulation of all 17 questions showed that no group clearly out-stupids the others. They appear about equally stupid when faced with proper challenges to their position.
  • Consistently, the more a statement challenged a group’s position, the worse the group did.
  • Education had very little impact on responses, we found; survey respondents who’d gone to college did only slightly less badly than those who hadn’t.
  • the fact that a college education showed almost no effect—at least for those inclined to take such a survey—strongly suggests that the classroom is no great corrective for myside bias. At least when it comes to public-policy issues, the corrective value of professional academic experience might be doubted as well.
Javier E

Summarizing EdTech in One Slide: Market, Open and Dewey - EdTech Researcher - Education Week - 0 views

  • My job is to introduce participants to the diverse landscape of the field of education technology. One of the biggest problems in the ed-tech space right now is that the phrase "education technology" means very different things to different people and organizations. Here's a 2x2 model that summarizes (and, of course, oversimplifies) the entire education technology space:
  • There are two important questions to ask any ed tech organization or advocate: 1) Are you trying to make a billion dollars? and 2) Do you believe that learning occurs primarily through "delivery?" By answering those two questions, we can put everyone in the ed-tech field into one of three groups: Market, Open and Dewey.
  • The "Market" people are those that are trying to make a billion dollars and believe that learning is fundamentally a process of delivery. These people typically believe that free markets are the ultimate tool for optimizing all outcomes in society, and education should be no exception
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  • They view learning as the process of delivering learning objects for the individual consumption of students, and they have great faith that this delivery process can be optimized by algorithms and data mining. It is incredibly important for them that we have quantifiable outcomes of learning (standardized tests), since they can only optimize on quantitative metrics.
  • the biggest players in the Open movement generally believe that learning is a process of algorthmically delivering learning objects to consumers, and they frequently use "supply and demand" models to conceptualize their efforts
  • The difference between Open and Market is that Open folks believe that learning objects are not commodities to be bought and sold, but the public infrastructure of our culture
  • They'd like learning objects and the algorithms distributing those objects to be openly licensed and free for teachers to reuse, remix, and re-publish.
  • The "Dewey" people reject the notion of learning as "delivery" and the free market as the best platform for learning.
  • Dewey is a complex figure, but when most people invoke him, they mean that learning occurs through people's experiences and not through content delivery
  • Learning occurs when teachers and students work together to create or make something with meaning to to people in the real world
  • They tend to believe that the nuanced, contextual, social experiences that lead to the best learning experiences are easiest to facilitate when the curriculum is not overly prescriptive.
Javier E

AMA: How a Weird Internet Thing Became a Mainstream Delight - Alexis C. Madrigal - The Atlantic - 0 views

  • hundreds of people have offered themselves up to be interrogated via Reddit's crowdsourced question-and-answer sessions. They open a new thread on the social network and say, for example, "IamA nanny for a super-rich family in China AMA!"
  • Then, the assembled Redditors ask whatever they want. Questions are voted up and down, and generally speaking, the most popular ones get answered. These interviews can last for as little as an hour or go on for several days.  googletag.cmd.push(function () { googletag.display("adIn-article3"); }); Politicians tend to play things pretty straight, but the regular people and niche celebrities tend to open up in fascinating ways. 
  • Over the last several years, the IamA subreddit has gone from interesting curiosity to a juggernaut of a media brand. Its syntax and abbreviations have invaded the public consciousness like Wired's aged Wired/Tired/Expired rubric. It's a common Twitter joke now to say, "I [did something commonplace], ask me anything." 
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  • Reddit was about to become the preeminent place for "real 'expert'" AMAs that were extremely useful and enlightening.
  • AMAs among common folk focus on dishing on what sex, disease, or jobs are really like. The celebrity versions borrow the same idea, but they serve up inside information on celebrity itself (generally speaking) or politics itself. 
  • The AMA is supposed to expose the mechanism. The AMA is about exposing the "inside conversations." The AMA is like the crowdsourced version of those moments when Kevin Spacey turns to the camera in House of Cards and breaks things down. 
Javier E

Creativity Becomes an Academic Discipline - NYTimes.com - 0 views

  • Once considered the product of genius or divine inspiration, creativity — the ability to spot problems and devise smart solutions — is being recast as a prized and teachable skill.
  • “The reality is that to survive in a fast-changing world you need to be creative,”
  • “That is why you are seeing more attention to creativity at universities,” he says. “The marketplace is demanding it.”
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  • Creativity moves beyond mere synthesis and evaluation and is, he says, “the higher order skill.” This has not been a sudden development. Nearly 20 years ago “creating” replaced “evaluation” at the top of Bloom’s Taxonomy of learning objectives. In 2010 “creativity” was the factor most crucial for success found in an I.B.M. survey of 1,500 chief executives in 33 industries. These days “creative” is the most used buzzword in LinkedIn profiles two years running.
  • The method, which is used in Buffalo State classrooms, has four steps: clarifying, ideating, developing and implementing. People tend to gravitate to particular steps, suggesting their primary thinking style.
  • What’s igniting campuses, though, is the conviction that everyone is creative, and can learn to be more so.
  • Just about every pedagogical toolbox taps similar strategies, employing divergent thinking (generating multiple ideas) and convergent thinking (finding what works).The real genius, of course, is in the how.
  • as content knowledge evolves at lightning speed, educators are talking more and more about “process skills,” strategies to reframe challenges and extrapolate and transform information, and to accept and deal with ambiguity.
  • Ideating is brainstorming and calls for getting rid of your inner naysayer to let your imagination fly.
  • Clarifying — asking the right question — is critical because people often misstate or misperceive a problem. “If you don’t have the right frame for the situation, it’s difficult to come up with a breakthrough,
  • Developing is building out a solution, and maybe finding that it doesn’t work and having to start over
  • Implementing calls for convincing others that your idea has value.
  • “the frequency and intensity of failures is an implicit principle of the course. Getting into a creative mind-set involves a lot of trial and error.”
  • His favorite assignments? Construct a résumé based on things that didn’t work out and find the meaning and influence these have had on your choices.
  • “Examine what in the culture is preventing you from creating something new or different. And what is it like to look like a fool because a lot of things won’t work out and you will look foolish? So how do you handle that?”
  • Because academics run from failure, Mr. Keywell says, universities are “way too often shapers of formulaic minds,” and encourage students to repeat and internalize fail-safe ideas.
  • “The new people who will be creative will sit at the juxtaposition of two or more fields,” she says. When ideas from different fields collide, Dr. Cramond says, fresh ones are generated.
  • Basic creativity tools used at the Torrance Center include thinking by analogy, looking for and making patterns, playing, literally, to encourage ideas, and learning to abstract problems to their essence.
  • students explore definitions of creativity, characteristics of creative people and strategies to enhance their own creativity.These include rephrasing problems as questions, learning not to instinctively shoot down a new idea (first find three positives), and categorizing problems as needing a solution that requires either action, planning or invention.
Javier E

'Trespassing on Einstein's Lawn,' by Amanda Gefter - NYTimes.com - 0 views

  • It all began when Warren Gefter, a radiologist “prone to posing Zen-koan-like questions,” asked his 15-year-old daughter, Amanda, over dinner at a Chinese restaurant near their home just outside Philadelphia: “How would you define nothing?”
  • “I think we should figure it out,” he said. And his teenage daughter — sullen, rebellious, wallowing in existential dread — smiled for the first time “in what felt like years.” The project proved to be a gift from a wise, insightful father. It was Warren Gefter’s way of rescuing his child.
  • Tracking down the meaning of nothing — and, by extension, secrets about the origin of the universe and whether observer-independent reality exists — became the defining project of their lives. They spent hours together working on the puzzle, two dark heads bent over their physics books far into the night.
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  • She became a science journalist. At first it was a lark, a way to get free press passes to conferences where she and her father could ask questions of the greatest minds in quantum mechanics, string theory and cosmology. But within a short time, as she started getting assignments, journalism became a calling, and an identity.
  • “If observers create reality, where do the observers come from?” But the great man responded in riddles. “The universe is a self-­excited circuit,” Wheeler said. “The boundary of a boundary is zero.” The unraveling of these mysteries propels the next 400 or so pages.
  • she has an epiphany — that for something to be real, it must be invariant — she flies home to share it with her father. They discuss her insight over breakfast at a neighborhood haunt, where they make a list on what they will affectionately call “the IHOP napkin.” They list all the possible “ingredients of ultimate reality,” planning to test each item for whether it is “real,” that is whether it is invariant and can exist in the absence of an observer.
  • their readings and interviews reveal that each item in turn is observer-dependent. Space? Observer-dependent, and therefore not real. Gravity, electromagnetism, angular momentum? No, no, and no. In the end, every putative “ingredient of ultimate reality” is eliminated, including one they hadn’t even bothered to put on the list because it seemed weird to: reality itself
  • What remained was an unsettling and essential insight: that “physics isn’t the machinery behind the workings of the world; physics is the machinery behind the illusion that there is a world.”
  • In the proposal, she clarifies how cosmology and quantum mechanics have evolved as scientists come to grips with the fact that things they had taken to be real — quantum particles, space-time, gravity, dimension — turn out to be ­observer-dependent.
Emily Freilich

Is the Man Who Is Tall Happy? - Movie Trailers - iTunes - 0 views

  •  
    Trailer for a movie of a collection of interviews with linguist Noam Chomsky. Some thought provoking questions are presented in the trailer. 
Javier E

Our Dangerous Inability to Agree on What is TRUE | Risk: Reason and Reality | Big Think - 1 views

  • Given that human cognition is never the product of pure dispassionate reason, but a subjective interpretation of the facts based on our feelings and biases and instincts, when can we ever say that we know who is right and who is wrong, about anything? When can we declare a fact so established that it’s fair to say, without being called arrogant, that those who deny this truth don’t just disagree…that they’re just plain wrong
  • This isn’t about matters of faith, or questions of ultimately unknowable things which by definition can not be established by fact. This is a question about what is knowable, and provable by careful objective scientific inquiry, a process which includes challenging skepticism rigorously applied precisely to establish what, beyond any reasonable doubt, is in fact true. The way evolution has been established
  • With enough careful investigation and scrupulously challenged evidence, we can establish knowable truths that are not just the product of our subjective motivated reasoning. We can apply our powers of reason and our ability to objectively analyze the facts and get beyond the point where what we 'know' is just an interpretation of the evidence through the subconscious filters of who we trust and our biases and instincts. We can get to the point where if someone wants to continue believe that the sun revolves around the earth, or that vaccines cause autism, or that evolution is a deceit, it is no longer arrogant - though it may still be provocative - to call those people wrong.
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  • here is a truth with which I hope we can all agree. Our subjective system of cognition can be dangerous. It can produce perceptions that conflict with the evidence, what I call The Perception Gap, which can in turn produce profound harm.
  • The Perception Gap can lead to disagreements that create destructive and violent social conflict, to dangerous personal choices that feel safe but aren’t, and to policies more consistent with how we feel than what is in fact in our best interest. The Perception Gap may in fact be potentially more dangerous than any individual risk we face.
  • We need to recognize the greater threat that our subjective system of cognition can pose, and in the name of our own safety and the welfare of the society on which we depend, do our very best to rise above it or, when we can’t, account for this very real danger in the policies we adopt.
  • we have an obligation to confront our own ideological priors. We have an obligation to challenge ourselves, to push ourselves, to be suspicious of conclusions that are too convenient, to be sure that we're getting it right.
  • subjective cognition is built-in, subconscious, beyond free will, and unavoidably leads to different interpretations of the same facts.
  • Views that have more to do with competing tribal biases than objective interpretations of the evidence create destructive and violent conflict.
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