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"Previous small-scale studies have failed to identify robust evidence of a benefit and larger, randomised controlled trials are not yet completed," Dr. Frank Ruschitzka, director of the Heart Center at University Hospital Zurich and the study's coauthor, said in a statement.

President Donald Trump has repeatedly touted hydroxychloroquine as a potential coronavirus cure. Earlier this week he claimed he was taking daily doses of it as a prophylaxis to prevent infection.

Items such as masks and hand sanitizer will be familiar sights in stuffed backpacks. Classes and school buses will have fewer people while some office meetings will be conducted by video conference, experts say.

Additionally, the study found serious cardiac arrhythmias were more common among patients who received any of the four treatments. The largest increase was among the group treated with hydroxychloroquine and an an antibiotic -- 8% of those patients developed a heart arrythmia, compared to 0.3% of the control group.

Children with underlying health conditions are especially vulnerable, and it's crucial that people follow rules to keep everyone safe, Altmann said. She shared other things US schools must address before unlatching their doors.

"We need to quickly test them, diagnose, isolate and then contact trace, which is a lot easier when there's fewer kids they've come into contact with throughout the day," Altmann added.

In New York, 16.6% of people have been infected, compared with 1% in California, the researchers said.

In the most severe scenario, the CDC assumes that 1% of people overall with Covid-19 and symptoms will die. In the least severe scenario, it puts that number at 0.2%.

"Go out, wear a mask, stay six feet away from anyone so you have the physical distancing," he said. "Go for a run. Go for a walk. Go fishing. As long as you're not in a crowd and you're not in a situation where you can physically transmit the virus."

Alaska is allowing all businesses to reopen, as well as houses of worship, libraries, museums and sporting activities, starting at 8 a.m. Alaska has the fewest cases of all states and has reported single-digit new cases since mid-April.

What happens inside a person’s head can have damaging effects throughout the body, as well as the other way around. An untreated mental illness can significantly increase the risk of becoming physically ill, and physical disorders may result in behaviors that make mental conditions worse.

In studies that tracked how patients with breast cancer fared, for example, Dr. David Spiegel and his colleagues at Stanford University School of Medicine showed decades ago that women whose depression was easing lived longer than those whose depression was getting worse. His research and other studies have clearly shown that “the brain is intimately connected to the body and the body to the brain,”

“The body tends to react to mental stress as if it was a physical stress.”

Anxiety disorders affect nearly 20 percent of American adults. That means millions are beset by an overabundance of the fight-or-flight response that primes the body for action.

“We often talk about depression as a complication of chronic illness,” Dr. Frownfelter wrote in Medpage Today in July. “But what we don’t talk about enough is how depression can lead to chronic disease. Patients with depression may not have the motivation to exercise regularly or cook healthy meals. Many also have trouble getting adequate sleep.”

These protective actions stem from the neurotransmitters epinephrine and norepinephrine, which stimulate the sympathetic nervous system and put the body on high alert. But when they are invoked too often and indiscriminately, the chronic overstimulation can result in all manner of physical ills, including digestive symptoms like indigestion, cramps, diarrhea or constipation, and an increased risk of heart attack or stroke.

While it’s normal to feel depressed from time to time, more than 6 percent of adults have such persistent feelings of depression that it disrupts personal relationships, interferes with work and play, and impairs their ability to cope with the challenges of daily life

“Depression diminishes a person’s capacity to analyze and respond rationally to stress,” Dr. Spiegel said. “They end up on a vicious cycle with limited capacity to get out of a negative mental state.”

Although persistent anxiety and depression are highly treatable with medications, cognitive behavioral therapy and talk therapy, without treatment these conditions tend to get worse.

When you’re stressed, the brain responds by prompting the release of cortisol, nature’s built-in alarm system. It evolved to help animals facing physical threats by increasing respiration, raising the heart rate and redirecting blood flow from abdominal organs to muscles that assist in confronting or escaping danger.

Improving sleep is especially helpful, Dr. Spiegel said, because “it enhances a person’s ability to regulate the stress response system and not get stuck in a mental rut.”

The photo was taken by Jennifer Foster, a civilian communications director for the Pinal County Sheriff’s Office in Arizona. She said the moment resonated for personal reasons: She remembered as a young girl seeing her father, a 32-year veteran of the Phoenix police force, buy food for a homeless man. “He squatted down, just like this officer,” she said.

[M]aybe the lesson is that the good life is not possible in the Philadelphia suburbs, or any place where in order to keep your head above water, your job has to own you and your wife, and it keeps you from building relationships.

The life Ruthie lived is a compelling alternative, the witness of which changed my heart. And like the Good Book says, “Where your treasure is, there will your heart be also.”

In support of that idea, half a dozen Nobel laureates and other prominent scientists are working with two small companies offering NR supplements.

This time his lab made headlines by reporting that the mitochondria in muscles of elderly mice were restored to a youthful state after just a week of injections with NMN (nicotinamide mononucleotide), a molecule that naturally occurs in cells and, like NR, boosts levels of NAD.

It should be noted, however, that muscle strength was not improved in the NMN-treated mice

a single dose of NR resulted in statistically significant increases” in NAD in humans—the first evidence that supplements could really boost NAD levels in people.

When NAD levels drop, as they do with aging, SIRT1 activity falls off, which in turn makes the crucial signals fade, leading to mitochondrial dysfunction and all the ill effects that go with it.

NAD boosters might work synergistically with supplements like resveratrol to help reinvigorate mitochondria and ward off diseases of aging

Test-tube and rodent studies also suggest that pterostilbene is more potent than resveratrol when it comes to improving brain function, warding off various kinds of cancer and preventing heart disease.

Even before Sinclair's paper, researchers had shown in 2012 that when given doses of NR, mice on high-fat diets gained 60 percent less weight than they did on the same diets without NR. Further, none of the mice on NR showed signs of diabetes, and their energy levels improved. The scientists reportedly characterized NR's effects on metabolism as "nothing short of astonishing."

The Sinclair group's NAD paper drew attention partly because it showed a novel way that NAD and sirtuins work together. The researchers discovered that cells' nuclei send signals to mitochondria that are needed to maintain their normal operation. SIRT1 helps insure the signals get through. When NAD levels drop, as they do with aging, SIRT1 activity falls off, which in turn makes the crucial signals fade, leading to mitochondrial dysfunction and all the ill effects that go with it.

Test-tube and rodent studies also suggest that pterostilbene is more potent than resveratrol when it comes to improving brain function, warding off various kinds of cancer and preventing heart disease.

You similarly don’t want to come crashing down on your knee so you break your kneecap or do that maneuver where you kind of pedal with your feet to catch yourself, which can lead to broken bones in your foot and ankle.

Paratroopers’ goal is to fall sideways in the direction the wind is carrying them — in no way resisting the momentum of the fall. When the balls of their feet barely reach the ground, they immediately distribute the impact in rapid sequence up through the calf to the thigh and buttocks.

Accept that you’re falling and go with it, round your body, and don’t stiffen and distribute the energy so you take the fall in the widest area possible,

Young children are arguably the best fallers because they have yet to develop fear or embarrassment, so they just tumble and roll without tensing up and trying to catch themselves.

“The most important thing when you study hypnosis is that you learn that humans are irrational,

what Trump is doing? He is acknowledging the suffering of some, Adams says, and then appealing emotionally to that.

2. Knowing that people are irrational, Trump aims to appeal on an emotional level.

Having nothing to lose essentially then increases his chance of winning, because it opens up his field of rhetorical play.

Within that context, here is what Candidate Trump is doing to win campaign hearts and minds

1. Trump knows people are basically irrational.

he bolsters that approach, Adams says, by “exploiting the business model” like an entrepreneur. In this model, which “the news industry doesn’t have the ability to change … the media doesn’t really have the option of ignoring the most interesting story,” says Adams, contending that Trump “can always be the most interesting story if he has nothing to fear and nothing to lose.”

“The evidence is that Trump completely ignores reality and rational thinking in favor of emotional appeal,” Adams writes. “Sure, much of what Trump says makes sense to his supporters, but I assure you that is coincidence. Trump says whatever gets him the result he wants. He understands humans as 90-percent irrational and acts accordingly.”

3. By running on emotion, facts don’t matter.

“There are plenty of important facts Trump does not know. But the reason he doesn’t know those facts is – in part – because he knows facts don’t matter. They never have and they never will. So he ignores them.

4. If facts don’t matter, you can’t really be “wrong.”

“If you understand persuasion, Trump is pitch-perfect most of the time. He ignores unnecessary rational thought and objective data and incessantly hammers on what matters (emotions).”

“Did Trump’s involvement in the birther thing confuse you?” Adams goes on to ask. “Were you wondering how Trump could believe Obama was not a citizen? The answer is that Trump never believed anything about Obama’s place of birth. The facts were irrelevant, so he ignored them while finding a place in the hearts of conservatives.

5. With fewer facts in play, it’s easier to bend reality.

Among the persuasive techniques that Trump uses to help bend reality, Adams says, are repetition of phrases; “thinking past the sale” so the initial part of his premise is stated as a given; and knowing the appeal of the simplest answer, which relates to the concept of Occam’s razor.

6. To bend reality, Trump is a master of identity politics — and identity is the strongest persuader.

“The best Trump linguistic kill shots,” Adams writes,”have the following qualities: 1. Fresh word that is not generally used in politics; 2. Relates to the physicality of the subject (so you are always reminded).”

: “Identity is always the strongest level of persuasion. The only way to beat it is with dirty tricks or a stronger identity play. … [And] Trump is well on his way to owning the identities of American, Alpha Males, and Women Who Like Alpha Males. Clinton is well on her way to owning the identities of angry women, beta males, immigrants, and disenfranchised minorities.

We cannot enrich the minds of our students by testing them on texts that purposely ignore their hearts. By doing so, we are withholding from our neediest students any reason to read at all. We are teaching them that words do not dazzle but confound. We may succeed in raising test scores by relying on these methods, but we will fail to teach them that reading can be transformative and that it belongs to them.

My own view of these things is that we simply do not know enough to judge the ultimate truth of the claims of theology. (I’m with Hamlet, who remarked to Horatio: “There are more things in heaven and earth … than are dreamt of in your philosophy.”) Perhaps we will one day; perhaps not. Meanwhile, given that religious faith is an intrinsic element of human experience, it is best to approach and engage the subject with a sense of history and a critical sensibility.

In his view that faith was “not a possession but a hope,” Hamilton was tapping into an ancient tradition. As the author of the New Testament Epistle to the Hebrews wrote, “Faith is the substance of things hoped for, the evidence of things not seen”—in this sense, religious faith is way of interpreting experience that allows for the possibility of the redemptive. Faith in this sense assumes that scripture and tradition are the works of human hands and hearts, efforts undertaken to explain the seemingly inexplicable. Faith in this sense is inextricably tied to doubt; it is an attempt, sometimes successful and sometimes not, to squint and struggle to “see through a glass darkly,” as Paul wrote in Corinthians. Faith without such doubt has never been part of the Christian tradition; it is telling, I think, that one of the earliest resurrection scenes in the Bible is that of Thomas demanding evidence—he wanted to see, to touch, to prove. Those who question and probe and debate are heirs of the apostles just as much as the most fervent of believers.

. DHEA is classified as a neurosteroid; in the same way that steroids help your body grow stronger from physical exercise, DHEA helps your brain grow stronger from psychological challenges. For several hours after you have a strong stress response, the brain is rewiring itself to remember and learn from the experience. Stress leaves an imprint on your brain that prepares you to handle similar stress the next time you encounter it.

Psychologists call the process of learning and growing from a difficult experience stress inoculation. Going through the experience gives your brain and body a kind of stress vaccine. This is why putting people through practice stress is a key training technique for NASA astronauts, Navy SEALS, emergency responders and elite athletes, and others who have to thrive under high levels of stress.

. (This is part of what makes the science of stress so fascinating, and also so puzzling.

Higher levels of cortisol have been associated with worse outcomes, such as impaired immune function and depression. In contrast, higher levels of DHEA—the neurosteroid—have been linked to reduced risk of anxiety, depression, heart disease, neurodegeneration and other diseases we typically think of as stress-related.

An important question, then, is: How do you influence your own — or somebody else’s — growth index?

This mindset can actually shift your stress physiology toward a state that makes such a positive outcome more likely, for example by increasing your growth index and reducing harmful side effects of stress such as inflammation.

Other studies confirm that viewing a stressful situation as an opportunity to improve your skills, knowledge or strengths makes it more likely that you will experience stress inoculation or stress-related growth. Once you appreciate that going through stress makes you better at it, it gets easier to face each new challenge. And the expectation of growth sends a signal to your brain and body: get ready to learn something, because you can handle this.

Of course it does. And words get really tired. They get well-tread, and ubiquitous, and diffuse, and they lose their original point of origin.  So I think that we can stop leaning on that one word and try to talk about all the aspects that affect our lives when a lot of money comes to town and people are displaced, and the character of the neighborhood changes.

There are a lot of class issues at the heart of capital coming to the neighborhood and displacement and all of these factors that are a part of what we loosely call gentrification. But at the end of the day, we can’t operate in a bubble in 2015. We have to acknowledge all the historic context, all the different forms of discrimination, particularly red-lining, these sorts of practices, that have made the class issue a race issue. At it’s heart it’s a class issue, but in the States, through our history, we’ve made it a race issue. It very much is a race issue.

There's nothing metaphorical about "gut feelings," for what happens in the gut really does influence what we feel. Nor is it just the gastrointestinal tract that alters our minds. Mr. Damasio has shown that neurological patients who are unable to detect changes in their own bodies, like an increased heart rate or sweaty palms, are also unable to make effective decisions

This research shows that the immateriality of mind is a deep illusion. Although we feel like a disembodied soul, many feelings and choices are actually shaped by the microbes in our gut and the palpitations of our heart.

More often, we fail to spot them altogether. D

To create this lexicon, they hired actors to mime the expressions, then asked volunteers to describe their meaning, taking the majority response as the accurate one.

The camera tracks 24 "feature points" on your conversation partner's face, and software developed by Picard analyses their myriad micro-expressions, how often they appear and for how long. It then compares that data with its bank of known expressions (see diagram).

Eventually, she thinks the system could be incorporated into a pair of augmented-reality glasses, which would overlay computer graphics onto the scene in front of the wearer.

the average person only managed to interpret, correctly, 54 per cent of Baron-Cohen's expressions on real, non-acted faces. This suggested to them that most people - not just those with autism - could use some help sensing the mood of people they are talking to.

set up a company called Affectiva, based in Waltham, Massachusetts, which is selling their expression recognition software. Their customers include companies that, for example, want to measure how people feel about their adverts or movie.

it's hard to fool the machine for long

In addition to facial expressions, we radiate a panoply of involuntary "honest signals", a term identified by MIT Media Lab researcher Alex Pentland in the early 2000s to describe the social signals that we use to augment our language. They include body language such as gesture mirroring, and cues such as variations in the tone and pitch of the voice. We do respond to these cues, but often not consciously. If we were more aware of them in others and ourselves, then we would have a fuller picture of the social reality around us, and be able to react more deliberately.

develop a small electronic badge that hangs around the neck. Its audio sensors record how aggressive the wearer is being, the pitch, volume and clip of their voice, and other factors. They called it the "jerk-o-meter".

it helped people realise when they were being either obnoxious or unduly self-effacing.

y the end of the experiment, all the dots had gravitated towards more or less the same size and colour. Simply being able to see their role in a group made people behave differently, and caused the group dynamics to become more even. The entire group's emotional intelligence had increased (

Some of our body's responses during a conversation are not designed for broadcast to another person - but it's possible to monitor those too. Your temperature and skin conductance can also reveal secrets about your emotional state, and Picard can tap them with a glove-like device called the Q Sensor. In response to stresses, good or bad, our skin becomes clammy, increasing its conductance, and the Q Sensor picks this up.

Physiological responses can now even be tracked remotely, in principle without your consent. Last year, Picard and one of her graduate students showed that it was possible to measure heart rate without any surface contact with the body. They used software linked to an ordinary webcam to read information about heart rate, blood pressure and skin temperature based on, among other things, colour changes in the subject's face

In Rio de Janeiro and Sao Paolo, police officers can decide whether someone is a criminal just by looking at them. Their glasses scan the features of a face, and match them against a database of criminal mugshots. A red light blinks if there's a match.

Thad Starner at Georgia Institute of Technology in Atlanta wears a small device he has built that looks like a monocle. It can retrieve video, audio or text snippets of past conversations with people he has spoken with, and even provide real-time links between past chats and topics he is currently discussing.

The US military has built a radar-imaging device that can see through walls to capture 3D images of people and objects beyond.

Much of the epidemiological data underpinning the government’s dietary advice comes from studies run by Harvard’s school of public health. In 2011, directors of the National Institute of Statistical Sciences analyzed many of Harvard’s most important findings and found that they could not be reproduced in clinical trials.

In 2013, government advice to reduce salt intake (which remains in the current report) was contradicted by an authoritative Institute of Medicine study. And several recent meta-analyses have cast serious doubt on whether saturated fats are linked to heart disease, as the dietary guidelines continue to assert.

In clearing our plates of meat, eggs and cheese (fat and protein), we ate more grains, pasta and starchy vegetables (carbohydrates). Over the past 50 years, we cut fat intake by 25 percent and increased carbohydrates by more than 30 percent, according to a new analysis of government data. Yet recent science has increasingly shown that a high-carb diet rich in sugar and refined grains increases the risk of obesity, diabetes and heart disease — much more so than a diet high in fat and cholesterol.

Today, we are poised to make the same mistakes. The committee’s new report also advised eliminating “lean meat” from the list of recommended healthy foods, as well as cutting back on red and processed meats. Fewer protein choices will likely encourage Americans to eat even more carbs. It will also have policy implications: Meat could be limited in school lunches and other federal food programs.

It’s possible that a mostly meatless diet could be healthy for all Americans — but then again, it might not be. We simply do not know. There are no rigorous clinical trials on such a diet, and although epidemiological data exists for adult vegetarians, there is none for children.

We have to start looking more skeptically at epidemiological studies and rethinking nutrition policy from the ground up.

Until then, we would be wise to return to what worked better for previous generations: a diet that included fewer grains, less sugar and more animal foods like meat, full-fat dairy and eggs