THERE is no drug — recreational or prescription — capable of inducing the tranquil euphoria brought on by swimming. I do all my best thinking in the pool, whether I’m trying to figure out how to treat a patient’s complicated ailment or write a paper.
Social Laughter Releases Endorphins in the Brain - 0 views
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Opinion | Pool of Thought - The New York Times - 0 views
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I could flood you with facts about the physiology of swimming in an attempt to convince you of its cognitive benefits. Some point to endorphins — but the idea that exertion causes endorphin levels to rise in the brain seems to be a myth
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Perhaps swimming improves brain function by increasing blood flow? Sure, that’s true. It also raises the level of BDNF, a protein that promotes neurogenesis, especially in the hippocampus, which supports memory. But so does nearly every form of exercise that speeds up your heart rate.
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Eric Kandel's Visions - The Chronicle Review - The Chronicle of Higher Education - 0 views
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Judith, "barely clothed and fresh from the seduction and slaying of Holofernes, glows in her voluptuousness. Her hair is a dark sky between the golden branches of Assyrian trees, fertility symbols that represent her eroticism. This young, ecstatic, extravagantly made-up woman confronts the viewer through half-closed eyes in what appears to be a reverie of orgasmic rapture," writes Eric Kandel in his new book, The Age of Insight. Wait a minute. Writes who? Eric Kandel, the Nobel-winning neuroscientist who's spent most of his career fixated on the generously sized neurons of sea snails
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Kandel goes on to speculate, in a bravura paragraph a few hundred pages later, on the exact neurochemical cognitive circuitry of the painting's viewer:
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"At a base level, the aesthetics of the image's luminous gold surface, the soft rendering of the body, and the overall harmonious combination of colors could activate the pleasure circuits, triggering the release of dopamine. If Judith's smooth skin and exposed breast trigger the release of endorphins, oxytocin, and vasopressin, one might feel sexual excitement. The latent violence of Holofernes's decapitated head, as well as Judith's own sadistic gaze and upturned lip, could cause the release of norepinephrine, resulting in increased heart rate and blood pressure and triggering the fight-or-flight response. In contrast, the soft brushwork and repetitive, almost meditative, patterning may stimulate the release of serotonin. As the beholder takes in the image and its multifaceted emotional content, the release of acetylcholine to the hippocampus contributes to the storing of the image in the viewer's memory. What ultimately makes an image like Klimt's 'Judith' so irresistible and dynamic is its complexity, the way it activates a number of distinct and often conflicting emotional signals in the brain and combines them to produce a staggeringly complex and fascinating swirl of emotions."
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A Placebo Treatment for Pain - The New York Times - 0 views
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This phenomenon — in which someone feels better after receiving fake treatment — was once dismissed as an illusion. People who are ill often improve regardless of the treatment they receive. But neuroscientists are discovering that in some conditions, including pain, placebos create biological effects similar to those caused by drugs.
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a key ingredient is expectation: The greater our belief that a treatment will work, the better we’ll respond.
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Placebo effects in pain are so large, in fact, that drug manufacturers are finding it hard to beat them. Finding ways to minimize placebo effects in trials, for example by screening out those who are most susceptible, is now a big focus for research. But what if instead we seek to harness these effects? Placebos might ruin drug trials, but they also show us a new approach to treating pain.
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