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By contrast, crystallised intelligence is based on experience and the accumulation of knowledge. Fluid intelligence peaks at the age of about 20 then gradually declines, whereas crystallised intelligence grows through your life until you hit your mid-sixties, when you start forgetting things.

that explains much about University Challenge’s appeal. Because the contestants are mostly aged around 20 and very clever, their fluid intelligence is off the scale

On the other hand, because they have had only 20 years to acquire crystallised intelligence, their store of general knowledge is likely to be lacking in some areas.

In each episode there will be questions that older viewers can answer, thanks to their greater store of crystallised intelligence, but the students cannot. Therefore we viewers don’t feel inferior when confronted by these smart young people. On the contrary: we feel, in some areas, slightly superior.

The first comprises the deconstructionists and decolonialists

It’s a brilliantly balanced format

They argue that all knowledge is contextual and that things taken for granted in the past — for instance, a canon of great authors that everyone should read at school — merely reflect an outdated, usually Eurocentric view of what’s intellectually important.

there is a real threat to the future of University Challenge and much else of value in our society, and it is this. The very concept of “general knowledge” — of a widely accepted core of information that educated, inquisitive people should have in their memory banks — is under attack from two different groups.

The other group is the technocrats who argue that the extent of human knowledge is now so vast that it’s impossible for any individual to know more than, perhaps, one billionth of it

So why not leave it entirely to computers to do the heavy lifting of knowledge storing and recall, thus freeing our minds for creativity and problem solving?

The problem with the agitators on both sides of today’s culture wars is that they are forcefully trying to shape what’s accepted as general knowledge according to a blatant political agenda.

And the problem with relying on, say, Wikipedia’s 6.5 million English-language articles to store general knowledge for all of us? It’s the tacit implication that “mere facts” are too tedious to be clogging up our brains. From there it’s a short step to saying that facts don’t matter at all, that everything should be decided by “feelings”. And from there it’s an even shorter step to fake news and pernicious conspiracy theories, the belittling of experts and hard evidence, the closing of minds, the thickening of prejudice and the trivialisation of the national conversation.

He and his colleagues could not replicate 47 of 53 landmark papers about cancer. Some of the results could not be reproduced even with the help of the original scientists working in their own labs.

Paradoxically the hottest fields, with the most people pursuing the same questions, are most prone to error, Dr. Ioannidis argued. If one of five competing labs is alone in finding an effect, that result is the one likely to be published. But there is a four in five chance that it is wrong. Papers reporting negative conclusions are more easily ignored.

The effect is amplified by competition for a shrinking pool of grant money and also by the design of so many experiments — with small sample sizes (cells in a lab dish or people in an epidemiological pool) and weak standards for what passes as statistically significant. That makes it all the easier to fool oneself.

The fear that much published research is tainted has led to proposals to make replication easier by providing more detailed documentation, including videos of difficult procedures.

A call for the establishment of independent agencies to replicate experiments has led to a backlash, a fear that perfectly good results will be thrown out.

Scientists talk about “tacit knowledge,” the years of mastery it can take to perform a technique. The image they convey is of an experiment as unique as a Rembrandt.

Embedded in the tacit knowledge may be barely perceptible tweaks and jostles — ways of unknowingly smuggling one’s expectations into the results, like a message coaxed from a Ouija board.

Exciting new results will continue to appear. But as the quarry becomes more elusive, the trophies are bound to be fewer and fewer.