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An international team of scientists has made a major step forward in our understanding of how enzymes 'edit' genes, paving the way for correcting genetic diseases in patients. Researchers at the Universities of Bristol, Münster and the Lithuanian Institute of Biotechnology have observed the process by which a class of enzymes called CRISPR - pronounced 'crisper' - bind and alter the structure of DNA. The results, published in the Proceedings of the National Academy of Sciences (PNAS) today, provide a vital piece of the puzzle if these genome editing tools are ultimately going to be used to correct genetic diseases in humans. CRISPR enzymes were first discovered in bacteria in the 1980s as an immune defence used by bacteria against invading viruses. Scientists have more recenty shown that one type of CRISPR enzyme - Cas9 - can be used to edit the human genome - the complete set of genetic information for humans. Did you know?? Blood Test Has Potential to Predict Alzheimer's