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Market Overview: Next-generation antibody therapeutics includes the use of new improvised therapeutic antibody to form innovative medicines for treating various diseases. Next-generation antibody therapeutics is developed clinically by pharmaceutical and biotechnology companies for several diseases. The Next Generation Antibody Therapeutics Market size was worth $ XX million in 2018 and is forecasted to reach $ XX million by 2026, expected to grow at a high CAGR during the forecast period 2019-2026. Market Dynamics: The Next Generation Antibody Therapeutics Market is growing due to several factors such as rising incidence of chronic diseases, increasing emergence of antibody technology, new drug discovery, large number of government initiatives, and growing research and development activities for new therapies. Rising prevalence of chronic disease such as cancer, asthma, diabetes and COPD are boosting the growth of the next generation antibody therapeutics market. For instance, according to National Cancer Institute in 2018, in United States, an estimated 1,735,350 new cases of cancer will be diagnosed and 609,640 people will die from the disease. The development of next-generation monoclonal antibodies has expanded beyond oncology into all therapeutic areas. For instance, ADCs were initially focused primarily on cancer, but Genentech has applied to infectious diseases, leading to the discovery and development of THIOMAB antibiotic conjugates (TACs) for the treatment of methicillin-resistant Staphylococcus aureus (MRSA). The technological advancements in antibody therapeutics have led to the development of more efficient antibody therapeutics, hence, driving the growth in the next-generation antibody therapeutics market. However, stringent government regulation, high cost and time required for research and development activities are some of the factors hindering the growth for global next-generation antibody therapeutics market. Market Segmentation: Based o

"An increase in brain inflammation, such as that caused by age, diabetes and obesity, is known to increase risk for developing Alzheimer's disease. Now scientists at UK's Southampton University are about to start a three-year study, using brain tissue generously donated by people who died with Alzheimer's disease, to see if inflammation caused by infections such as those of the urinary tract or chest, also speeds up progress of the disease." - medical news today In an announcement released on Wednesday, study leader Delphine Boche, Lecturer in Clinical Neurosciences at Southampton, says: "Many of the known risk factors for Alzheimer's, like age, obesity and diabetes, increase inflammation in the brain and we think that infections could be another risk factor." "There is already evidence that the immune system is on high alert in people with Alzheimer's and we think that an extra trigger, like an infection, could tip the balance and make immune cells switch from being protective to harmful," she adds. Alzheimer's Research UK has already put £300,000 into the project. The money is part of the charity's £20m investment in leading dementia research in the UK. The study started in January 2013, and will add to the growing pile of evidence that shows how the immune system is implicated in Alzheimer's disease. The Southampton team believes that in Alzheimer's, the immune system goes beyond its role as protector of the body and starts causing damage, like it does in an autoimmune disease. For their study, Boche and colleagues will use brain tissue generously donated by people who had Alzheimer's disease when they died. With reference to donors' medical records, the researchers will compare the brains of those who had infections when they died with those who did not. They will be particularly interested in immune cells known as "microglia", which go around mopping up cellular debris. They will use fluorescent tags to label the cells in the brain, and look

Market Overview: Skin substitutes are natural, synthetic or biosynthetic materials, used to cover large wounds to restore at least some of the functions of the skin. Skin substitutes provides temporary or permanent wound closure and protect the wound from infection, further damage and water loss, and reduce pain. They also facilitate the growth of the normal skin over the wound. Skin substitutes provide a permanent solution and are used in the treatment of conditions like burns, trauma wounds, diabetes or venous ulcers, where skin grafts may not be possible. Market Dynamics: Rising chronic skin diseases is expected to drive the skin substitutes market. For instance, according to the global burden of disease study 2013, Skin conditions contributed around 1.79% to the global disease burden. According to the World Health Organization, about 132,000 melanoma skin cancers occur each year worldwide. Thus, the rising chronic diseases is increasing the demand for skin substitutes in the forecast period. Rising prevalence of diabetes is expected to boost the market. This is owing to the risk of developing a diabetic foot ulcer over the period of time in diabetic patients. For instance, WHO has reported that the incidence of diabetes for all age-groups worldwide was estimated to be 2.8% in 2000 and 4.4% in 2030. The total number of people with diabetes is anticipated to rise from 171 million in 2000 to 366 million in 2030. Thus, as a consequence, the prevalence of diabetes related complications are expected to increase over the forecast period. There are several limitations to the commercially available skin substitutes, like reduced vascularization, poor mechanical integrity, failure to integrate, scarring, and immune rejection. Market Segmentation: Rise in preference for acellular skin substitutes to implant-based skin surgery is expected to drive the growth of the skin substitutes market. For instance, the American Society of Plastic Surgeons in 2012, reported that

Anti-aging without Surgery - Afraid to age but more afraid of knives and undergo surgery? We always look for the best things and best ways on how to avoid looking old. Have you ever wonder how to reclaim your youth while you do not have to go under the knife? For the millions of people that have sun spots and scars on the surface of their skin that become more prevalent with age, Zapiach said laser technology has vastly improved over the past decade, with patients seeing full results in about three months. Patients looking to turn back the hands of time have a non-invasive option that was most commonly associated with pregnancy: ultrasound unlike before when face lifts used to be the way to go for patients looking to tighten up the saggy, loosening of the facial skin that comes with age. All of us will age and as a part of aging process more and more physical features will vanish along the way. We lose volume in places like our eye sockets, cheeks and jaw line. The doctor has the solution for that, Fillers and injectables, although he said that those are temporary. It will last anywhere from six months to a year but will on depend on the one you choose. A non-invasive procedure that uses a patient's own fat is permanent though. But the doctor warned that not everyone is a candidate for non-invasive procedures. Dr. Zapiach also cautioned that patients with advanced aging may have to resort to surgical options. "Ultherapy actually has an indication to lift and tighten that area . . . as well as the neck and also the eyebrows," said Zapiach. "We'll see results in the cheeks that it will lift and tighten the cheeks and jowls as well." Cigarette Smoking is Dangerous to your Health! - Smoking effects on the human body are destructive and widespread. The ingredients in cigarette affect everything from the internal functioning of the organs and target the efficiency of the body's immune system. Smoking harms nearly every organ of the body. Smoking

Influenza A virus or more known to us as H5N1 is an avian (bird) flu, an influenza A subtype that has caused outbreaks in domestic poultry in parts of Asia and the Middle East. This is deadly to them and is considered "highly pathogenic" meaning highly disease causing. Although the virus does not usually infect people but infectious that these viruses occurred in humans. Most of these cases have resulted from people having direct or close contact with H5N1-infected poultry or H5N1-contaminated surfaces. There are three types of viruses, A, B, and C, that can cause flu to human. The type A is characterized not only to human but to other mammals and birds too. The virus transmitted by air. The type A virus is composed of two obligatory protein components. One is called hemagglutinin and is lettered H, and the other-neuraminidase (N). And there are 13 variants of hemagglutinin and 9 of neuraminidase, which then can characterized what type of virus it is. Making H5N1 is just out of the many possible variants of the virus structure. Many parts of the world has been infected by the virus such as Asia, parts of Europe, the Near East Africa, birds as well as half of the humans infected did not survive. The outbreaks infected poultry and wild birds, and humans who have direct contact with the infected animal. In most cases, healthy children and young adult and have resulted from direct contact with H5N1-infected poultry or contaminated surfaces were infected. The H5N1 virus does not infect humans easily and in general it remains very rare disease in people. If the person is infected it is not that easy to spread it to another human. However, there has been some human-to-human spread of the virus although it is limited. But scientists are anxious that H5N1 virus one day could infect humans then spread easily from person-to-person because viruses such as influenza have the ability to change. Although at the moment that the virus do not com

Taco Bell was well-known as one of the purveyor of junk food and they wanted to start erasing that from our memory yet they are not ready to give up the chalupa yet. Wednesday, the chain announced that it's exploring ways to offer more "balanced choices," marking just the latest sign that the fast-food industry is trying to adapt to shifting tastes and upend the conventional wisdom that it only offers caloric indulgences. Taco Bell is testing a "range of products" this year, with national launches planned for 2014. He also said existing menu items could also be reformulated but noted that the chain would remain true to its brand, CEO Greg Creed said. "We're not going to walk away from who Taco Bell is," Creed stated. Taco Bell says, by 2020, 20% of its combo meals will meet nutritional guidelines for calories and fat set out by the federal government. People eat three meals a day, as a general thought, that means a single meal would have about a third of the recommended intake of about 2,000 to 2,500 calories. The company has no idea of what portion of meals currently meet those guidelines. Taco Bell is known for urging people to eat nachos as a "fourth meal" late at night, it is a bit of a contrary to the announcement and it gained a lot of skeptics. However it demonstrates just how much difficulty the broader industry is facing to overturn its greasy-food image as people more and more look out for alternatives they believe are healthier. The lower-calorie options were a key indicator of growth at restaurant chains between 2006 and 2011 from a report by the Hudson Institute earlier this year. The increase in customer traffic rise by 11 per cent by those chains that expanded while those that didn't saw traffic fall by 15 per cent, according to the public policy research group. As customer "tastes and needs" evolve, Creed said that offering more balanced choices would be critical in helping Taco Bell reach its growth targets over the next

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NBC Bay Area >> A Los Angeles man was sentenced to six years in prison last week for his role in a power wheelchair scam, topping what prosecutors say has been a series of Medicare fraud cases. David James Garrison, 50, a former physician assistant, was found guilty by a federal jury for his role in submitting $18.9 million in fraudulent Medicare claims for power wheelchairs and other equipment. The wheelchair case is the third time Garrison has been accused of Medicare fraud. Garrison's physician assistant license lapsed in 2009, said Russ Heimerich, a spokesman for the Department of Consumer Affairs, which oversees many state licensing boards. He said the board examined the tax evasion case and did not see it as grounds for discipline. According to court documents, Garrison's cases involved the use of "cappers" or "marketers" who recruited Medicare beneficiaries to submit to unneeded care or hand over their personal information. That information was used to bill the program for medications, services or supplies that the patients didn't need. In the wheelchair case, prosecuted by the Los Angeles U.S. attorney's office, one witness testified that marketers had to recruit beneficiaries as far as 300 miles from Los Angeles because so many local people had already been used in other fraud schemes. In the first health fraud case linked to Garrison, he was described as an "at large" suspect in October 2007 when then-Attorney General Jerry Brown announced arrests in a $1.5 million health fraud scam.