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Introduction of biodegradable fillers proves to be major opportunity in the market as they get resorbed overtime by tissues and require repetitive applications, thus generating major share of revenue for manufacturing companies.

In the recent past, new injectable fillers are popping up in the industry. In total, there were 17890 treatments with non-permanent dermal fillers in the Netherlands for the year 2015. The CE certification is the official way to introduce a new product onto the European market. Polymethyl-methacrylate microspheres (PMMA) is considered a semi-permanent filler, often used to treat medium-to-deep wrinkles, furrows and folds, mostly nasolabial folds.