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Religion, although it is not the best method of determining moral norms, has often been very effective at promoting them. Religions often satisfy many of Daleiden's criteria for raising people to be conditioned egoists, especially by practicing the aforementioned elements of prosocial training. He suggests that this is what they are doing when they instill a sense of virtue and justice, right and wrong.

Aldous Huxley's novel Brave New World and George Orwell's 1984 imagine dystopian future societies that control the populace by advanced scientific techniques. Harris argues that moral scientists approaching truths does not imply an "Orwellian future" with "scientists at every door". Instead, Harris imagines data about normative moral issues being shared in the same way as other sciences (e.g. peer-reviewed journals on medicine).

Science of morality should identify basic components required for human flourishing, drawing heavily on findings from positive psychology. In a proto-scientific example, Abraham Maslow suggested a hierarchy of needs: basic physical survival, then social and self esteem needs, and lastly philosophical and self-actualization.

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Research looking for optimal ethical systems can draw on all the methods of science, especially those used by positive psychology. While this might include obvious methods like asking people to self-report what they think they need to flourish in life – psychology has shown that people are often surprisingly incorrect on these matters (particularly when it comes to making predictions and recollections). Some cases in point: having too many varieties of consumer goods actually creates consumer choice anxiety; when it comes to removing bandages, Dan Ariely's research suggests that "getting it over with as quickly as possible" may cause more negative memories than if one went slowly (with breaks) while being careful never to reach a 'peak' in pain; stress is not always harmful (such stress is called eustress). While very careful use of self-report can still be illuminating (e.g. bogus pipeline techniques), in the end, unconscious methods of inquiry seem to be more promising. Some unconscious methods of data collection include the Implicit Association Test and neuroimaging. In these ways, science can further our understanding of what humans need to flourish, and what ways of organizing society provide the greatest hope for flourishing.

Extensive study of cooperation has shed some light on the objective (and subjective) advantages of teamwork and empathy. The brain areas that are consistently involved when humans reason about moral issues have been investigated by a quantitative large-scale meta-analysis of the brain activity changes reported in the moral neuroscience literature.[76] In fact, the neural network underlying moral decisions overlapped with the network pertaining to representing others' intentions (i.e., theory of mind) and the network pertaining to representing others' (vicariously experienced) emotional states (i.e., empathy).

There is evidence to suggest that a risk factor for becoming victims of bullying is deficient moral development. Examples of deficient moral development may be something like neglecting an agent's intentions during an action, or blaming them for accidents. In other words, victims of bullying may be more likely to make less accurate moral assessments, for some reason. The researchers also found that, in contrast, bullies were just as morally developed as victim defenders. The difference is that bullies are more able to disengage themselves. That is, for whatever reason, bullies end up suppressing their feelings of compassion and conscience.[77]